Clinical trials: Dental Treatment
Endodontic Disease, Endodontically Treated Teeth
Outcome of Endodontic Treatment and Retreatment With a Bioceramic Sealer
This study is a prospective randomized controlled study of patients who come to the University. The aim is to evaluate the success rate of treatment and retreatment of canals using BioRoot ™ RCS cement compared with AH Plus up to…
- Trial name
- NCT04528979
- Testing
- BioRoot RCS® root canal sealer, AH Plus® root canal sealer
- Where
- Spain
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Juan Gonzalo Olivieri
Dental Anxiety
Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation
There is still extensive debate on the best method of controlling the behavior of preschool children during dental treatment. Protective stabilization, moderate sedation and general anesthesia are advanced behavior control…
- Trial name
- NCT02284204
- Testing
- Midazolam, Ketamine and Sevoflurane, Midazolam and Ketamine
- Where
- Brazil
- Volunteers
- 27 people
- Sponsor
- Universidade Federal de Goias
Dental Anxiety
Efficacy of Iatrosedation and Music Therapy to Attenuate Dental Anxiety
Dental anxiety is a common problem encountered in the dental clinics that affect both patients and dentists. Adequate management of the dental anxiety is critical for optimal treatment outcomes of the patient.
- Trial name
- NCT05755126
- Testing
- Iatrosedation, Musical Therapy
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Peri-implantitis, Peri-Implant Health
Reconstructive Therapy for Peri-implantitis Using Tuberosity Bone with or Without Electrolytic Cleaning: a Randomized Clinical Trial
This study aims to evaluate the effectiveness of two surgical approaches for managing peri-implantitis, a condition characterized by inflammation and bone loss around dental implants.
- Conditions
- Peri-implantitis, Peri-Implant Health, Peri-Implantational Loss, Peri-Implantation Loss
- Trial name
- NCT06708247
- Testing
- Standard Peri-implant Reconstructive Surgery, Electrolytic Cleaning with Peri-implant Reconstructive Surgery
- Where
- Lithuania
- Volunteers
- 31 people
- Sponsor
- Vilniaus Implantologijos Centro (VIC) Klinika
Tooth Erosion, Teeth Erosion Due to Vomiting
Clinical Evaluation of Ultrathin Occlusal Veneers for the Treatment of Severe Dental Erosion
Ultra-thin bonded posterior occlusal veneers represent a conservative alternative to traditional onlays and complete coverage crowns for the treatment of severe erosive lesions.
- Conditions
- Tooth Erosion, Teeth Erosion Due to Vomiting, Teeth Erosion Limited to the Enamel, Teeth Erosion Extending Into the Dentine
- Trial name
- UOVTDE (NCT03112278)
- Testing
- Ceramic ultrathin occlusal veneers, Composite resin ultrathin occlusal veneers
- Volunteers
- 10 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Distraction, Behavior Management
Video-Enhanced Tell-Show-Do for Managing Dental Anxiety in Children
This study is the first of its kind to examine the effect of integrating the real oral environment with a video that supports the expressions used during the Tell-Show-Do technique (such as "we will see the cavity," "the cavity…
- Trial name
- NCT07632547
- Testing
- Behavioral Treatment
- Where
- Syria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damascus University
Endodontic Disease
Treatment Outcome of Ortho MTA (BioMTA®) Cement vs AH Plus® Bioceramic Sealer (Dentsply).
The use of bioceramics materials as root canal fillings in endodontics is gaining traction due to their excellent biocompatibility, antibacterial and sealing abilities.
- Trial name
- NCT05984940
- Testing
- Ortho MTA cement, GP and AH Plus sealer
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- National University Hospital, Singapore
Gingivitis and Periodontal Diseases, Gingivitis; Chronic
Guided Biofilm Therapy Compared to Traditional Cleaning for Treating Gingival Inflammation in Orthodontic Patients
Why is this study being done? This study is for people with braces who have gum inflammation (gingivitis), which is when gums are swollen and bleed easily.
- Conditions
- Gingivitis and Periodontal Diseases, Gingivitis; Chronic, Gingivitis, Gingival Bleeding
- Trial name
- NCT07355517
- Testing
- Guided Biofilm Therapy, Traditional Ultrasonic Scaling + Polishing
- Where
- Jordan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Desensitization, Dental Anxiety
Impact of Dental Desensitization Facilitated by a Child Life Specialist Distress and Cooperation
The aim of this study is to evaluate whether dental desensitization visits facilitated by a Certified Child Life Specialist (CCLS) significantly impact pediatric patients' distress and cooperation levels from the start of…
- Conditions
- Desensitization, Dental Anxiety, Dental Care, Distress, Emotional
- Trial name
- NCT06620289
- Testing
- Dental Desensitization Clinic
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Colorado
Apical Periodontitis, Postoperative Pain
Effectiveness of Different Obturation Techniques
Aim: Evaluation of the effect of different obturation techniques on postoperative pain level and radiographic healing on non-surgical endodontic retreatment (NSER) applied in a single visit in teeth with single root canal and…
- Conditions
- Apical Periodontitis, Postoperative Pain, Endodontically Treated Teeth
- Trial name
- NCT06226740
- Testing
- Single Visit Non Surgical Root Canal Treatment Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Endodontically Treated Molar, Dental Restoration, Permanent
3D Printed Ceramic-Filled Photopolymer Resin Vs. CAD/CAM Resin Composite Overlays for Restoration of Extensively Damaged Endodontically Treated Posterior Teeth. An 18-month Follow-up
II. Introduction: 6. Background and rationale: Restoring badly mutilated teeth was and has always been a challenge in restorative dentistry.
- Trial name
- 3D CAD/CAM RCT (NCT07378982)
- Testing
- 3D printed overlay restorations, CAD/CAM restorations
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Dental Implant in Compromised Adjacent Sockets
Management of Multiple Adjacent Extraction Sockets
While early implant placement with guided bone regeneration (GBR) offers advantages, the desire for reduced treatment time and fewer surgical steps continues to drive the exploration of alternative approaches.
- Trial name
- VST (NCT07063836)
- Testing
- VST, contour augmentation and early implant placement
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Orthodontics, Dental Hygiene
Evaluation of the Effect of a Probiotic in Patients Undergoing Orthodontic Therapy
Orthodontic patients need supplementary oral hygiene tools in addition to professional oral hygiene. The aim of this study is to evaluate the effects of Bifidobacterium animalis subs.
- Conditions
- Orthodontics, Dental Hygiene, Gingivitis and Periodontal Diseases
- Trial name
- NCT06752330
- Testing
- Use of probiotics during oral hygiene at home
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Pulp Exposure, Dental, Pulp Disease, Dental
The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy
This study employs saliva-based DNA analysis to investigate the effect of genetic polymorphisms, particularly SNPs in MMP, TIMP, TNF-α, and BMP genes, on the success of vital pulp therapy in permanent teeth with pulpitis…
- Conditions
- Pulp Exposure, Dental, Pulp Disease, Dental, Pulp Caping, Pulpitis
- Trial name
- NCT07130214
- Testing
- Biodentine
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ataturk University
Child Behavior
Effect of Sensory Adapted Dental Environment on Children's Behavior During Dental Treatment
The objective of the present study is to determine the effect of sensory adapted dental environment (SADE) in healthy children during a routine dental restorative treatment.
- Trial name
- NCT03366467
- Testing
- SADE, RDE
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dentin Hypersensitivity, Periodontal Diseases
Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients
The present project will compare the effect of DH reduction using three different dentifrices (Sensodyne Repair and Protect - NOVAMIN technology; Dentalclean Daily Regenerator - REFIX technology; Dentalclean Daily Regenerator …
- Trial name
- NCT04422184
- Testing
- Sensodyne Repair and Protect, Dentalclean Daily Regenerator, Dentalclean Daily Regenerator with potassium citrate
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Endodontic Disease, Dental Implant Failed
Retreat or Replace: Retrospective Investigation on a Cohort of Local Patients
Introduction: To evaluate the survival and success rate of premolars with a previous root canal treatment which underwent to non-surgical retreatment or to extraction and implant replacement.
- Conditions
- Endodontic Disease, Dental Implant Failed, Periapical Diseases
- Trial name
- NCT06250114
- Testing
- Retreatment, extraction implant
- Volunteers
- 130 people
- Sponsor
- University of Bologna
Dental Caries
Conservative Versus Non-conservative Treatment for Severe Dental Caries
The purpose of this study is to compare the effectiveness of the conservative (pulpectomy) versus non-conservative treatment (tooth extraction) of primary molars affected with severe dental caries associated to oral…
- Trial name
- NCT01858298
- Testing
- Conservative treatment: pulpectomy and composite resin crown, Non-conservative treatment: Tooth extraction
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Dental Anxiety
Cognitive Behavioural Treatment of Intra-oral Injection-phobia in 10-16 Year Old Children and Adolescents
The aims of the study: to explore the possible effectiveness of cognitive behavior treatment (CBT) among children and adolescents with formally diagnosed intra-oral injection phobia (DSM-IV), when performed by specially trained…
- Trial name
- NCT02083432
- Testing
- 5 session of CBT performed by specially trained dentists
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
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