Clinical trials: Dental Treatment
Pain
Evaluation of the Efficacy of Novel Ibuprofen Acetaminophen Combination Formulations in the Treatment of Post-surgical Dental Pain
This study will determine the overall analgesic efficacy of three different fixed dose ibuprofen plus acetaminophen formulations compared to ibuprofen alone and to placebo.
- Trial name
- NCT01559259
- Testing
- Ibuprofen/acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 394 people
- Sponsor
- Pfizer
Dental Atraumatic Restorative Treatment
Clinical Evaluation of Enamel Microhardness Using Tooth Whitening Agents
The investigator will review the medical history taken by the participants' orthodontist that determined participants eligibility to participate in this study on the first appointment.
- Trial name
- NCT07165366
- Testing
- Carbamide Peroxide 10%, Hydrogen Peroxide
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ultradent Products, Inc.
Dentin Sensitivity
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex…
- Trial name
- NCT02919202
- Testing
- Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride., Self-etching Dentine Bonding Agent
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Kent
Dental Caries
Comparison Between Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary Teeth
Objective: The study's main purpose is to evaluate and compare the clinical and radiographic outcomes of Biodentine and a light-activated calcium hydroxide based-liner (Ultra-Blend plus®) as indirect pulp treatment (IPT) liners…
- Trial name
- IPT (NCT02799927)
- Testing
- Indirect Pulp Treatment with Bioactive Dentin Substitute, Indirect Pulp treatment with Calcium hydroxide
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- José Arturo Garrocho Rangel
Symptomatic Irreversible Pulpitis
Vital Pulp Therapy Versus Root Canal Treatment for Irreversible Pulpitis With Incipient Apical Periodontitis Diagnosed Using Artificial Intelligence This Keeps: the Main Intervention (Vital Pulp Therapy) the Comparison (Root Canal Treatment) the Condition (Irreversible Pulpitis With Incipient Apic
This study evaluates postoperative pain and treatment outcomes following vital pulp therapy and root canal treatment in patients with symptomatic teeth.
- Trial name
- NCT07549620
- Testing
- Vital Pulp Therapy, Root Canal Treatment
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Ain Shams University
Dental Fear
A Stepped Care Approach to Treating Dental Fear
The purpose of this study is to compare an intervention for dental fear to the usual approach (i.e., whatever participants' dentist typically does to help participants manage their fear).
- Trial name
- NCT06024395
- Testing
- A stepped-care approach to the treatment of dental fear; Dental Fearless
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- New York University
Dental Implants
Vestibular Socket Therapy (VST) Versus Partial Extraction Therapy
The current randomized clinical trial aimed to compare the VST versus Partial Extraction Therapy (PET) for immediate implant placement in the esthetic zone in class I fresh extraction sites.
- Trial name
- NCT05112796
- Testing
- Class I extractions sites received immediate implants using the Vestibular Socket Therapy, class I extractions sites received immediate implants using the Partial Extraction Therapy
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman
Dental Caries Extending to Pulp, Molar Incisor Hypomineralization
Vital Pulp Therapy in Carious Teeth With Hypomineralization
Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth.
- Trial name
- NCT03735069
- Testing
- IPT (Indirect pulp treatment), Cvek/partial pulpotomy, Cervical pulpotomy
- Where
- Jordan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pulpitis
Buffered Versus Conventional Local Anesthesia for Pain and Anxiety Reduction in School-Aged Children With Pulpitis
The objective of this clinical trial is to evaluate whether buffered local anesthesia is more effective than conventional local anesthesia in reducing pain responses in school-aged children requiring dental treatment for…
- Trial name
- NCT07638254
- Testing
- Buffered Lidocaine with Epinephrine, idocaine with Epinephrine (Conventional)
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Immediate Dental Implant
The Effect Of Hyaluronic Acid And Melatonin With Systemic Administration of Vitamin C On Implant Stability After Immediate Implant in Anterior Region
The concept of immediate implant placement at the time of tooth extraction was first introduced by Schulte et al. on animal studies.
- Trial name
- NCT03804177
- Testing
- immediate implant placement with melatonin hyaluronic acid vit C, immediate implant placement without melatonin hyaluronic acid vit C
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Treatment, Periodontitis, Apical
Treatment of Young Permanent Teeth With Different Adjuvant Approaches
To determine microbiology assessment of infected root canal in young permanent teeth, as well as antimicrobial efficiency of different adjuvant treatment modalities including photodynamic therapy (PDT), high-power diode laser…
- Conditions
- Treatment, Periodontitis, Apical, Necrotic Pulp
- Trial name
- NCT05291195
- Testing
- Laser-device group, Essential Oil, Sodium hypochlorite group
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Dental Anxiety
Comparative Clinical Study Between Virtual Reality Hypnosis and Nitrous Oxide Inhalation for Dental Anxie
The vicious circle of dental anxiety impacts major aspects of a child's quality of life. Hypnosis using distraction is one of the most common non-pharmalogical techniques in behavior and pain management in pediatric dentistry.
- Trial name
- HYPNOSEDENT (NCT05167331)
- Testing
- Nitrous Oxide inhalation, Dispositif de RV - HYPNO VR
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Dental Anxiety
Computer Assisted Relaxation Learning for Dental Offices
This is a randomized study in which two groups will be used to compare the effectiveness of a computerized psychological therapy compared to an information only control group (pamphlet) for reducing fear of dental injections.
- Trial name
- CARL (NCT00609648)
- Testing
- Computer Assisted Relaxation Learning, Pamphlet
- Where
- 5 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy, Tooth Disease
Evaluation of Patients With Unusual Diagnostic or Treatment Considerations
This study offers evaluation and treatment of patients with unusual diagnostic or treatment considerations. It is not designed to test new treatments; rather, patients will receive current standard of care treatments.
- Trial name
- NCT00001182
- Testing
- current standard of care treatments
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Periodontitis
The Safety and Tolerability of Initial Periodontal Therapy Combined With Human Dental Pulp Stem Cell Injection in the Treatment of Chronic Periodontitis
The principal objective of this trial is to investigate the safety and tolerability of human dental pulp stem cells injection in the treatment of chronic periodontitis.
- Trial name
- NCT04983225
- Testing
- Human Dental Pulp Stem Cells, Saline solution
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Peking University Third Hospital
Mixed Dentition Using Sequential Dental Aligners
This Study Will Examine Shortened Treatment Wear Time for Patients With Mixed Dentition Using AirFlex Aligner, Sequential Dental Aligners.
This study will examine shortened treatment wear time for patients with mixed dentition using sequential dental aligners. Using the existing AirFlex aligner design that patients with permanent dentition use, it may be possible to…
- Trial name
- NCT07220317
- Testing
- Sequential Aligners
- Volunteers
- 45 people
- Sponsor
- OrthoFX
Premedication
Oral Dexmedetomidine vs Midazoam For Premedication
The aim of this study was to compare the effect of 2 µg/kg of oral dexmedetomidine (DEX) and 0.5 mg/kg dormicum as premedication among children undergoing dental procedures.
- Trial name
- NCT03357718
- Testing
- Precedex, Midazolam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Intubation; Difficult or Failed, Postoperative Pain
The Comparison of Direct Macintosh Laryngoscopy and HugeMed Video Laryngoscope for Nasotracheal Intubation in Children
Forty-four patients aged 4-10 years who applied to Aydın Adnan Menderes University Faculty of Dentistry for dental treatment under general anesthesia will be selected and divided into 2 groups by simple randomization.
- Trial name
- NCT05121597
- Testing
- HugeMed Videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Dental Anxiety, Pain
Virtual Reality Distraction During Restorative Dental Treatment
This split-mouth randomized clinical trial will evaluate the effect of virtual reality (VR) distraction on pain perception, anxiety, physiological responses, and patient experience during local anaesthesia administration and…
- Trial name
- NCT07738718
- Testing
- Virtual Reality Headset, Standard Dental Treatment
- Where
- Saudi Arabia
- Volunteers
- 13 people
- Sponsor
- Qassim University
Endodontic Disease, Endodontically Treated Teeth
Outcome of Endodontic Treatment and Retreatment With a Bioceramic Sealer
This study is a prospective randomized controlled study of patients who come to the University. The aim is to evaluate the success rate of treatment and retreatment of canals using BioRoot ™ RCS cement compared with AH Plus up to…
- Trial name
- NCT04528979
- Testing
- BioRoot RCS® root canal sealer, AH Plus® root canal sealer
- Where
- Spain
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Juan Gonzalo Olivieri