Clinical trials: Dental Treatment
Periodontal Diseases, Adverse Effects
Effect of Non-surgical Periodontal Treatment
Objective: The objective of this research was to compare the effect of a single session supragingival scaling in a group of pregnant women with periodontal disease with a group that received supra and subgingival scaling.
- Trial name
- EONSPT (NCT01533792)
- Testing
- Supra/subgingival scaling using periodontal curette scraping, Supra and subgingival scaling
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Maranhão
Vital Pulp Therapies, Pulpotomy
Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars
The purpose of this RCT is to compare the clinical/radiographic outcomes of Potassium nitrate in polycarboxylate cement and MTA as pulpotomy biomaterials used for asymptomatic vital primary lower second molar and this will help…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Pulp Disease, Dental, Pulpotomies Primary Teeth
- Trial name
- NCT06871709
- Testing
- Potassium Nitrate in Polycarboxylate cement, MTA-Anglus
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Fear
The Effect of Reading a Pictorial Storybook on Children's Fear, Anxiety and Emotional Symptoms Before Dental Treatment
The aim of this study was to determine the effect of reading a picture storybook on children's fear, anxiety and emotional symptoms before dental treatment.
- Trial name
- NCT06142227
- Testing
- Reading a Pictorial Storybook
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gamze Akay
Laser Therapy, Low-Level
Clinical Study of Biostimulation With Low-Power Diode Laser After Dental Extractions
the objective of the present work is to assess the efficacy of photobiomodulation (PBM) with respect to pain, inflammation, and healing after tooth extractions as compared with a sham treatment
- Trial name
- CSBE (NCT06943391)
- Testing
- laser
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Universidad de Murcia
Postoperative Dental Pain
A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)
The purpose of this study is to compare the pain relieving effect of different doses of MK0663 with placebo and other pain relievers/analgesics in patients with postoperative dental pain.
- Trial name
- NCT00694369
- Testing
- Comparator: etoricoxib, Comparator: ibuprofen, Comparator: acetaminophen + codeine
- Volunteers
- 588 people
- Sponsor
- Organon and Co
Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment
Application of Advanced Platelet-Rich Fibrin Plus (A-PRF+) in Revascularisation of Necrotic Immature Permanent Teeth
The goal of this clinical trial is to evaluate the effectiveness of an advanced platelet-rich fibrin plus (A-PRF+) revascularization procedure to promote healing and root development in necrotic immature permanent single-rooted…
- Conditions
- Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment, Pulp Regeneration, Root Maturation
- Trial name
- A-PRF+ (NCT07092488)
- Testing
- Advanced Platelet-Rich Fibrin Plus (A-PRF+) Revascularization Procedure
- Where
- Croatia
- Volunteers
- 28 people
- Sponsor
- University of Zagreb
Molar Incisor Hypomineralization
Restorative Treatment in First Molars Affected by Molar-Incisor Hypomineralization
The restorative management of molars with Molar-Incisor Hypomineralization (MIH) represents a challenge in the clinical practice with high failure rate.
- Trial name
- NCT02717286
- Testing
- restorative
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Paraná
Chronic Periodontitis
Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets
This is a controlled, randomized, single-blinded, multicenter, prospective clinical study. In addition to the standard periodontal treatment procedure on all teeth that need to be treated, the 4 teeth with the deepest pockets…
- Trial name
- NCT02391974
- Testing
- PERIOSYAL FILL
- Where
- 3 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Tooth Wear, Dental Restoration Failure
Restorative Treatment of Severe Tooth Wear; Direct vs Indirect
This study compares the survival rates of both direct and indirect resin-based composite restorations in the treatment of severe tooth wear.
- Conditions
- Tooth Wear, Dental Restoration Failure, Dental Restoration Wear
- Trial name
- NCT04326816
- Testing
- Rehabilitation of severely worn dentitions using minimally invasive composite restorations (Estenia C&B or Clearfil AP-X, Kuraray, Osaka, Japan)
- Volunteers
- 42 people
- Sponsor
- Radboud University Medical Center
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq
Dental Pain
Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain
The purpose of this study is to assess the activity of buprenorphine hydrochloride (HCl) buccal film in the treatment of dental pain.
- Trial name
- NCT00941304
- Testing
- Oxycodone, Buprenorphine
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- BioDelivery Sciences International
Periapical Diseases, Postoperative Dental Pain
Postoperative Pain in Photodynamic Therapy Using Curcumin As a Photosensitizer
In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with photodynamic therapy, has…
- Conditions
- Periapical Diseases, Postoperative Dental Pain, Irrigation Solution, Photodynamic Therapy (PDT)
- Trial name
- NCT06752655
- Testing
- Curcumin with photodynamic thearpy, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Dental Crowding
Early Orthodontic Treatment of Dental Crowding
Aim of the study is to compare treatment duration and effects of orthodontic treatment of dental crowding between treatments started at different stages of mixed dentition phase.
- Trial name
- NCT04756843
- Testing
- Quad-helix
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Helsinki
Dental Anxiety
Computer Assisted Relaxation Learning for Dental Offices
This is a randomized study in which two groups will be used to compare the effectiveness of a computerized psychological therapy compared to an information only control group (pamphlet) for reducing fear of dental injections.
- Trial name
- CARL (NCT00609648)
- Testing
- Computer Assisted Relaxation Learning, Pamphlet
- Where
- 5 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Stem Cells, Dental Pulp Regeneration
Feasibility of the Preparation of an Advanced Therapy Medicinal Product for Dental Pulp Regeneration
Current endodontic treatment are based essentially on the ouster of parenchyma in case of trauma or irreversible pulp inflammation. These situations typically affect immature teeth in subjects aged from 8 to 15 years.
- Trial name
- Pulp'R (NCT02842515)
- Testing
- teeth avulsion
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pediatric Dentistry, Dental Anesthesia
Survey on Knowledge and Acceptance of Dental General Anesthesia for Children Among Different Populations
This is a cross-sectional, questionnaire-based study conducted in China. The purpose of this study was to investigate the knowledge and acceptance of pediatric dental general anesthesia among different populations, including…
- Trial name
- NCT07622719
- Testing
- Questionnaire-based survey
- Where
- 2 sites in China
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Cerebral Palsy
Conscious Sedation With Nitrous Oxide in Control of Stress During Dental Care for Individuals With Cerebral Palsy
Cerebral Palsy induces oral alterations that impact on oral health, requiring dental treatment. The objective of this study was to evaluate the use of conscious sedation with nitrous oxide (N2O) in the control of stress during…
- Trial name
- NCT02322983
- Testing
- Control of Stress
- Where
- Brazil
- Volunteers
- 77 people
- Sponsor
- Universidade Cruzeiro do Sul
Caries
A Strategy to Prevent the Recurrence of Dental Disease in Children Receiving Dental Treatment With General Anesthesia
The purpose of this study is to evaluate the effectiveness of a preventive strategy in increasing return to follow up and recall appointments.
- Trial name
- NCT05212142
- Testing
- verbal education, verbal education, visual aids, and motivational interviewing
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Virginia Commonwealth University
Dental Caries, Early Caries Lesion
Effect of Ozone Therapy on Remineralization of Initial Caries Lesions in Children
Initial caries lesions can be managed using non-invasive treatment approaches that promote remineralization and prevent lesion progression.
- Trial name
- OZONE-CARIES (NCT07671651)
- Testing
- Ozone Therapy, other
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Neslihan Atmaca
Obstructive Sleep Apnea
Side Effects of the Mandibular Advancement Device for Apnea Treatment on Dental Occlusion and Masticatory Function
This study evaluates the effect of the use of mandibular advancement devices (MAD) on dental occlusion and masticatory function during the first two years of obstructive sleep apnea (OSA) treatment.
- Trial name
- NCT05420129
- Testing
- MAD Therapy, CPAP Therapy
- Where
- Spain
- Sponsor
- University of Barcelona
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