Clinical trials: Dental Treatment
Oral Lichen Planus, Dental Plaque
Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP
This study is designed to investigate the effectiveness of plaque control intervention by home-use dual-light aPDT Lumoral -device as an adjunctive or alternative treatment to triamcinolone acetonide (TCA) mouth rinse or other…
- Conditions
- Oral Lichen Planus, Dental Plaque, Oral Bacterial Infection
- Trial name
- RELIEF-OLP (NCT05401201)
- Testing
- Lumoral treatment, Standard oral hygiene self care
- Where
- 2 sites in Finland
- Volunteers
- 13 people
- Sponsor
- Koite Health Oy
Children's Dental Anxiety
Virtual Reality Distraction and Dental Anxiety Among Anxious Pediatric Patients
Objective: This study evaluated the effect of Virtual Reality Distraction (VRD) on dental anxiety among anxious children undergoing prophylactic dental treatment by utilizing both subjective (Venham Anxiety and Behavioral Rating…
- Trial name
- NCT05663619
- Testing
- Virtual Reality Distraction during dental treatment of children., Control: watching cartoon on screen as distraction during dental treatment of children.
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Abdulaziz University
Dental Implant, Surgical Dental Prostheses
Low Intensity Pulsed Ultrasound Versus Low Level Laser Therapy Post Dental Implant
The purpose of the study is to investigate the significance difference between low intensity pulsed ultrasound (LIPUS) versus low-level laser therapy (LLLT) on osseointegration, soft tissue healing, pain pressure threshold and…
- Conditions
- Dental Implant, Surgical Dental Prostheses, Dental Implantation
- Trial name
- NCT05938868
- Testing
- Low intensity pulsed ultrasound (LIPUS), low level diode laser therapy, Standard Care
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Ahram Canadian University
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Caries, Dental
Atraumatic Restorative Treatment Sealants in First Permanent Molars
The aim of this bi-center study was to evaluate the retention and caries-preventive effect of Atraumatioc Restorative Treatment (ART) sealants, using two glass ionomer cement (GIC) versus non-sealant on first permanent molars of…
- Trial name
- NCT03667768
- Testing
- Glass ionomer sealant, Non-sealant (toothbrushing)
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Vital Signs Changes During Dental Procedures
Vital Signs Changes During Dental Procedures
The study will evaluate the vital signs changes during 3 different dental procedures performed for the same patient by the same dentist. The patients will be selected randomly and should all be healthy adults.
- Trial name
- NCT02788890
- Testing
- Scaling without LA, Simple restoration under LA, Simple exodontia under LA
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Dental Implant Placement, Ozone Therapy
Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability
This randomized split-mouth controlled clinical trial aims to compare the effects of ozone and conventional implant site disinfection on primary and early secondary implant stability.
- Trial name
- NCT07687680
- Testing
- Ozone Implant Site Disinfection, Conventional Socket Disinfection
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Zeliha Başak Çakır Erdil
Endodontic Disease, Endodontic Inflammation
Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment
Purpose: To evaluate anesthetic efficacy and overall patient experience with use of Kovanaze tetracaine/oxymetazoline nasal spray for root canal treatment of vital premolar and anterior teeth needing root canal treatment.
- Conditions
- Endodontic Disease, Endodontic Inflammation, Local Anesthesia, Dental Anesthesia
- Trial name
- NCT03502135
- Testing
- Tetracaine HCl and oxymetazoline HCl nasal spray
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hypomineralization of Enamel, Dental Fear
Analysis of Treatment Outcomes in Patients Affected by Molar-Incisor Hypomineralization (MIH)
The aim is to long-term evaluate extraction or restoration therapy, of first permanent molars with extensive treatment needs as a result of severe MIH in a national multicenter study concerning dental fear and anxiety, oral…
- Conditions
- Hypomineralization of Enamel, Dental Fear, Quality of Life
- Trial name
- GuREx-MIH (NCT06228989)
- Testing
- Restorative therapy, Extraction therapy
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Dental Implant Failed
Vetsibular Socket Therapy Versus Buser's Technique
immediate implant placement using the VST was compared to early implant placement protocol using Buser's technique regarding implant survival, changes in labial plate thickness and soft tissue height after 1 year of implant…
- Trial name
- VST (NCT04787237)
- Testing
- VST and immediate implants, Buser technique and early implants placement
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Periodontitis
Influence of Gum Disease Treatment on Long-term Dental Implant Success
The aim of this study is to evaluate the influence of periodontal care response on long term dental implant success. Investigator's hypothesis is that patients who do not well respond to periodontal care have more chance to…
- Trial name
- NCT03841656
- Testing
- PARORISKIMPLANT
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Pain and Anxiety in Children With MIH
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with…
- Trial name
- NCT07374354
- Testing
- ibuprofen 100mg/ml oral suspension syrup
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- October University for Modern Sciences and Arts
Implant, Peri-Implantitis
Efficacy of Diode Laser in Peri-implantitis
The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis.
- Conditions
- Implant, Peri-Implantitis, Alveolar Bone Loss, Complications
- Trial name
- NCT02362854
- Testing
- Conventional peri-implantitis treatment, DL application in peri-implantitis
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Root Caries
Non-invasive Treatment of Root Caries in Older Adults
This study aims to test the effectiveness in reducing or arresting root caries lesion in community-dwelling elderly subjects by using high fluoridated toothpaste.
- Trial name
- MIT-RCTalca (NCT02647203)
- Testing
- Self-administered fluoridated dentifrices
- Where
- Chile
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University of Talca
Dental Caries Extending Into Dentin
Antibacterial Effect of Light-activated Calcium Silicate Versus Light-activated Calcium Hydroxide
This is a randomized clinical study. 48 subjects with a confirmed diagnosis of deep carious molars without pulpal lesions were randomized to one of two treatments: Patients treated with Light-cured calcium silicate (Theracal)…
- Trial name
- NCT03214770
- Testing
- TheraCal, light-cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Child Discomfort
Child Discomfort and Parental Acceptability of Silver Diamine Fluoride and Alternative Restorative Treatment
The aim of the current study was to compare pain perception of young children treated with SDF and ART, as well as their parents' acceptability of both modalities.
- Trial name
- NCT04654624
- Testing
- SDF, ART
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Nourhan M.Aly
Periodontitis
The Efficacy and Safety of PerioChip Plus (Flurbiprofen/Chlorhexidine) Formulation in the Therapy of Adult Periodontitis
The purpose of this study is to determine the effect of the placement of a PerioChip Plus (flurbiprofen/chlorhexidine - FBP/CHX) formulation versus PerioChip (chlorhexidine) formulation versus Flurbiprofen Chip formulation versus…
- Trial name
- NCT00425451
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Dexcel Pharma Technologies Ltd.
Dental Caries, Patient Compliance
A Study to Compare Caries Detection in the Pediatric Population Between the iTero Element 5D System and Bitewing Radiographs
This is a non-significant risk, single site, prospective clinical study. The study will be conducted in the department of pediatric dentistry of the faculty of dental medicine of the Hebrew university, Israel
- Trial name
- NCT05792631
- Testing
- Near infra red imaging
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Pulp Necrosis
Root Canal Treatment in Primary Molars With Necrotic Pulp Using Two Different Pulp Therapies
This is a controlled, randomized, double-blind clinical study (researcher and research participant does not know which group they belong to), with the objective of evaluating clinical and radiographic performances of primary…
- Trial name
- NCT03650036
- Testing
- Pulp Therapy CTZ Paste, Pulp Therapy ZOE Paste
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- Federal University of Piaui
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