Clinical trials: Dental Treatment
Caries, Dental
Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children
The aim of this study is to determine the effectiveness of Er:YAG pulse therapy for achieving pulpal analgesia in pediatric patients and to quantify the duration and extent of any effects assessed.
- Trial name
- NCT03412721
- Testing
- Laser analgesic procedure
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Dental Implants
Peri-implant Soft Tissue Volume Changes at Small Buccal Dehiscences
This study was designed to assess peri-implant soft tissue health, volume and marginal stability at implants sites which presented small buccal bone dehiscences (<3mm evaluated in a vertical direction) at the time of insertion.
- Trial name
- NCT05466006
- Testing
- Soft tissue augmentation with subepithelial connective tissue graft (SCTG), Soft tissue augmentation with xenogenic volume stable collagen matrix (VCXM)
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Head and Neck Cancer, Head and Neck Carcinoma
Post-Radiation Oral Health in Underserved Head and Neck Cancer Patients
This is a pilot study evaluates the feasibility and outcomes of providing fluoride varnish treatment during routine cancer surveillance visits for post-radiation head and neck cancer patients with limited access to dental care.
- Conditions
- Head and Neck Cancer, Head and Neck Carcinoma, Head and Neck Neoplasms
- Trial name
- NCT07556367
- Testing
- Surveys, Saliva Collection, Intra-oral photographs
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of California, San Francisco
Unsatisfactory or Defective Restoration of Tooth
The Performance of Posterior Partial Coverage Coronal Restorations Luted With Two Differrent Systems.
This study explores an alternative approach using a pre-heated restorative resin composite as a luting material of partial coverage restorations on upper and lower posterior teeth.
- Trial name
- NCT06457737
- Testing
- IPS Empress Direct, Bisco Duo-Link Universal
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Crowding, Alveolar Bone Loss
Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults
This study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces.
- Conditions
- Dental Crowding, Alveolar Bone Loss, Malocclusion
- Trial name
- NCT07716007
- Testing
- Fixed orthodontic appliance, Clear aligners
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dental Implants
Computer Guided Versus Free Hand Immediate Implant Placement
Patients with remaining root or fractured teeth indicated for extraction in the esthetic zone will be recruited to the study. After extraction of the tooth implant will be placed immediately, implants will be placed either by…
- Trial name
- NCT03230500
- Testing
- Computer guided implant placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anxiety, Behavioral Management
Effect of Dental Anxiety Management by Integrative Music-mindfulness Intervention Among Iraqi Adult Patients in a Karbala City Private Clinic, an RCT Study
Dental anxiety considered as one of the weariest problems and disturbing problems with which the individual dentist has had to fight.
- Trial name
- NCT05844878
- Testing
- Distraction technique by using music therapy., Mindfulness technique by using of relaxation breathing with muscle relaxation
- Where
- 2 sites in Iraq, Malaysia
- Volunteers
- 288 people
- Sponsor
- University of Malaya
Pain
Efficacy of Lumiracoxib in Relieving Moderate to Severe Post-dental Surgery Pain, Compared to Both Placebo and Celecoxib
This study will assess the safety and efficacy of lumiracoxib 400 mg in relieving moderate to severe post-dental surgery pain, compared to both placebo and celecoxib 400 mg.
- Trial name
- NCT00348491
- Testing
- Lumiracoxib
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Novartis Pharmaceuticals
Dental Implant, Wound Healing
Lactoferrin Nanohydrogel for Soft And Hard Tissue Healing and Implant Stability in Immediate Implant Placement
The goal of this randomized clinical trial is to evaluate whether local application of a 4% bovine lactoferrin nanohydrogel improves soft tissue healing, bone healing, and implant stability following immediate dental implant…
- Trial name
- LF (NCT07889674)
- Testing
- 4% bovine lactoferrin nanohydrogel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Future University in Egypt
Pulpal Necrosis, Dental Caries
Comparison of LSTR and Pulpectomy in Primary Molars of Pediatric Patients (LSTR-PULP)
This study aims to compare the effectiveness of Lesion Sterilization and Tissue Repair (LSTR) with conventional pulpectomy in treating pulpal lesions in primary molars of pediatric patients aged 4 to 10 years.
- Conditions
- Pulpal Necrosis, Dental Caries, Periapical Periodontitis, Pediatric Dentistry
- Trial name
- LSTR-PULP (NCT07026435)
- Testing
- LSTR, Pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- taymour abuawwad
Dental Caries in Children
Experimental Research on Deep Carious Lesion Treatment of Molars
Maintaining dental pulp vitality is crucial for tooth preservation and functionality. Untreated dental caries may lead to pulp necrosis and infection, affecting children's growth and well-being.
- Trial name
- VITAPULP (NCT03626740)
- Testing
- TheraCal, MTA
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Postoperative Pain After Endodontic Treatment, Dental Anxiety
Effect of Intracanal Cryotherapy on Pain, Anxiety, and Salivary Irisin After Root Canal Treatment
Some people feel pain after a root canal treatment. This study will test whether intracanal cryotherapy, a final rinse of the tooth with cold sterile saline, can reduce this pain compared with a room-temperature rinse.
- Conditions
- Postoperative Pain After Endodontic Treatment, Dental Anxiety, Root Canal Treatment
- Trial name
- CRYO-IRISIN (NCT07889050)
- Testing
- Intracanal cryotherapy, Standard room-temperature irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Dental Caries, Early Caries Lesions
A Randomized Split-Mouth Clinical Trial Comparing Resin Infiltration and Microabrasion for Early Caries Lesions
This study aims to evaluate and compare the clinical characteristics and treatment outcomes of early caries lesions using resin infiltration (Icon) and microabrasion (Opalustre).
- Conditions
- Dental Caries, Early Caries Lesions, White Spot Lesions[Initial Caries]on Smooth Surface of Tooth
- Trial name
- ICON-CTU (NCT07544849)
- Testing
- Resin Infiltration, Microabrasion
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Peri Implant Mucositis, Peri Implantitis
Study on the Treatment of Dental Implants Using the AmbiJet System for Peri-implantitis and Peri-implant Mucositis
Inflammation of the tissue surrounding a dental implant (peri-implantitis or peri-implant mucositis) can lead to implant loss in advanced stages.
- Trial name
- AmbiJet-FIH (NCT07722715)
- Testing
- AmbiJet cold plasma system, Standard Mechanical Debridement (S3 Guideline)
- Where
- Ukraine
- Volunteers
- 26 people
- Sponsor
- Freiburger Medizintechnik GmbH
Endodontically Treated Teeth
Marginal Integrity and Clinical Evaluation of Polyetheretherketone (PEEK) Versus Lithium Disilicate (E-max) Endocrowns.
Patients need Endocrowns for their teeth usually use Emax as an etchable ceramic. Yet they have disadvantages that may influence the outcome of the endocrowns, among which is the high stiffness and rigidity owing to the higher…
- Trial name
- NCT04023357
- Testing
- PEEK, Emax
- Volunteers
- 22 people
- Sponsor
- Cairo University
Pain, Strength
Physical Therapy Intervention in Dental Students
The main purpose of our study is to assess whether guided strength training and stretching intervention with a written home exercise program is more effective than a home exercise program alone for pre-clinical dental students in…
- Conditions
- Pain, Strength, Quality of Life
- Trial name
- NCT05851586
- Testing
- Supervised exercise + home exercise program, Home exercise program only
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Joshua Subialka
Dental Occlusion, Primary Teeth
Digital Occlusal Analysis and Bite Force Evaluation of Primary Molars Restored With Zirconia Crowns Using T-Scan
The goal of this observational study is to evaluate the adaptation of occlusion and bite force after zirconia crown restoration in children with pulp-treated primary molars.
- Conditions
- Dental Occlusion, Primary Teeth, Pulp-treated Primary Molars, Zirconia Crowns
- Trial name
- NCT07276841
- Testing
- Pulp Therapy and Zirconia Crown Restoration of Primary Molars with T-Scan Occlusal Analysis
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University
Alveolar Ridge Resorption, Bone Loss in the Esthetic Zone
Clinical and Radiographic Evaluation of CGF and Alloplastic Grafting in Participants Undergoing the Socket Shield Technique for Immediate Anterior Maxillary Implant Placement. This Study Assesses Bone Healing and Stability When Managing the Crestal Gap in the Esthetic Zone.
The goal of this clinical trial is to evaluate the clinical and radiographic effectiveness of the socket shield technique combined with concentrated growth factor (CGF) and alloplastic graft in promoting bone healing and…
- Conditions
- Alveolar Ridge Resorption, Bone Loss in the Esthetic Zone, Socket Shield Technique, Partial Extraction Therapy
- Trial name
- CGF (NCT07514871)
- Testing
- Socket Shield Technique with CGF and Alloplastic Graft.
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Gingivitis, Bleeding Gum
Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment
A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the prevention and management of complications associated gingivitis by film forming action.
- Trial name
- NCT04438421
- Testing
- Filming mouthwash formulation, enriched with Hydrogen Peroxide and Hyaluronic Acid, Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Tobacco Cessation, Dental Practice
To Promote Tobacco Free Life in the Dental Practice in France
In France, 34% of the adult population is smoking every day. The links between smoking and the development of several chronic disorders is well established and smoking is directly implicated in most of the oral diseases such as…
- Trial name
- TOBAFREE-DP (NCT04498858)
- Testing
- Patient interview
- Where
- France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
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