Clinical trials: Dental Treatment
Endodontically Treated Teeth, Permanent Molars
Endocrowns as Permanent Restorations for Endodontically Treated Permanent Molars in Young Age: Two-Year Follow up
Background: A real challenge faces practitioners in dealing with permanent molars in young patients starting from proper selection of endodontic treatment system till the type of final coronal restoration.
- Trial name
- NCT04511117
- Testing
- Control group, Endocrown group
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Al-Azhar University
Dentin Sensitivity
Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may control dental sensitivity.
- Trial name
- NCT03434782
- Testing
- In-office dental bleaching, Low Level Laser Therapy, 5% potassium nitrate / 2% sodium fluoride gel
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Damaged Oral Mucosa
Evaluation of Mouthwash Use in Hygiene and Recovery After Interventions in Gums
The goal of this study was to learn if mouthwash works in aiding the healing of the gum tissue after trauma or dental procedure.
- Trial name
- NCT07385586
- Testing
- Repairing mouthwash
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lacer S.A.
Dental Anxiety, Pain
Nitrous Oxide Prior to Intranasal Midazolam for Moderate Dental Sedation in Pediatric Patients
The purpose of this study is to assess the effectiveness of nitrous oxide/oxygen administration in reducing the discomfort of intranasal midazolam administration for moderate sedation for dental procedures.
- Trial name
- NCT04083105
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Colorado
Intellectual and/or Physical Disabilities, Dental Treatment Under General Anesthesia
Retrospective Database Study: Survival of Direct Composite Restorations Placed Under General Anesthesia in Adult Patients With Intellectual and/or Physical Disabilities and Risk Factors for Repeated Dental Treatment in General Anesthesia
The aim of this study is to assess the survival of direct anterior and/or posterior composite restoration placed in general anesthesia in permanent teeth of adult patients with intellectual and/or physical disabilities.
- Trial name
- NCT04407520
- Testing
- No patient treatment is associated with the study
- Volunteers
- 101 people
- Sponsor
- University of Göttingen
Dental Anxiety
Dental Anxiety in Children and Salivary Cortisol Levels
Objective: This study aimed to assess whether pediatric dental anxiety is due to the day of dental appointment, to the dental chair, or to the dental treatment procedure during the course of the first dental treatment in…
- Trial name
- NCT04338854
- Testing
- Restorative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingival Recession
Treatment of Local Gingival Recession With an Enamel Matrix Protein Coated Collagen Matrix
The clinical trial studies patients with gingival recession defects (receding gums). The goal of the study is to test whether the additional use of enamel matrix derivatives (EMD), combined with the use of a coronally advance…
- Trial name
- EmdoDerm (NCT05799859)
- Testing
- Use of coronally advanced flap (CAF) and collagen matrix (CM), Use of coronally advanced flap (CAF) and collagen matrix (CM) and additional application of enamel matrix derivatives (EMD).
- Volunteers
- 15 people
- Sponsor
- Medical University of Graz
Acute Pain
A Study to Assess Efficacy and Tolerability of Ketoprofen 40 mg Granules vs Placebo
Primary objective: To assess the efficacy of OKITASK® 40 mg granules versus Placebo in patients with acute pain syndrome after removal of one molar tooth by comparing AUC0-6h of posttreatment pain profile measured by VAS.
- Trial name
- KSL0117 (NCT03836807)
- Testing
- OKITASK®
- Where
- 3 sites in Russia
- Volunteers
- 70 people
- Sponsor
- Dompé Farmaceutici S.p.A
Vital Pulp Therapy
Diagnostic Biomarkers to Correlate Molecular Changes and Inflammatory Cascade in the Dental Pulp.
This study aimed to evaluate the molecular changes that occur within the pulp tissue during inflammation and its correlation with vital pulp therapy with its different treatment modalities (Direct pulp capping, Partial Pulpotomy…
- Trial name
- NCT05464797
- Testing
- Pulp therapy, Cytokines level in pulpal blood.
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulpitis, Apical Periodontitis
Clinical and Microbiological Evaluation of 0.5% Versus 3% Sodium Hypochlorite in Root Canal Treatment
Aim: To compare the clinical antimicrobial and adverse effects of irrigation with Sodium Hypochlorite (NaOCl) 0.5% versus NaOCl 3% during root canal treatment.
- Trial name
- NCT02681276
- Testing
- Irrigation with 3% NaOCl, Irrigation with 0.5% NaOCl
- Where
- Sweden
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Dental Trauma, Crown Fractures
Evaluation and Treatment of Crown Fractures Using the Modified Baysal Dental Trauma Index
This study will be conducted by the Department of Pediatric Dentistry, Faculty of Dentistry, İnönü University, with the aim of evaluating the treatment processes and follow-up responses of patients aged between 6 and 14 years who…
- Conditions
- Dental Trauma, Crown Fractures, Tooth Fractures
- Trial name
- NCT07131462
- Testing
- Direct Composite Restoration, Cvek Pulpotomy, Endodontic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Inonu University
Pulp Therapy, Pulpitis - Irreversible
Evaluation of Pulpotomy Versus Pulpectomy in Primary Molars With Irreversible Pulpitis or Necrotic Pulp
Preserving primary teeth until their normal exfoliation time is crucial for maintaining the child's normal function, esthetics, arch integrity, and correct eruption of permanent successors.
- Conditions
- Pulp Therapy, Pulpitis - Irreversible, Pulp Necrosis
- Trial name
- NCT07230717
- Testing
- Pulpotomy, Pulpectomy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University
Dental Crowding
Accuracy and Time Efficiency of AI Versus Manual Segmentation in Adult Crowding Using Aligner Software
The purpose of this study is to evaluate how accurately and quickly artificial intelligence (AI) can separate individual teeth from digital dental scans of adults with dental crowding.
- Trial name
- AI-MAS (NCT07919652)
- Testing
- Automated tooth segmentation and manual segmentation
- Where
- Egypt
- Volunteers
- 155 people
- Sponsor
- Dina ahmed
Dental Pulp Diseases, Dental Pulp Necrosis
Non-instrumentation Root Canal Treatment of Primary Molars
This randomized clinical trial intended to evaluate the efficacy of a technique of root canal treatment of deciduous molars with non-instrumentation of root canals and use of a paste containing antibiotics (chloramphenicol and…
- Trial name
- EndoDecide-1 (NCT04942158)
- Testing
- Non-instrumentation technique with use of CTZ paste, Instrumentation technique and filling with Zinc Oxide and Eugenol paste
- Where
- 4 sites in Brazil
- Volunteers
- 180 people
- Sponsor
- University of Sao Paulo
Diagnoses Disease
Effect of Cone Beam Computed Tomography on Diagnostic and Therapeutic Decision Making
this study will determine the effect of CBCT examinations on diagnostic and therapeutic decision making in endodontics.
- Trial name
- NCT04689126
- Testing
- surgical or nonsurgical endodontic treatment
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Dental Anxiety
Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment
The aim of the study is to evaluate the effect of nebulized Midazolam, Dexmedetomidine, and their combination as procedural, moderate sedative agents in preschoolers undergoing dental treatment.
- Trial name
- NCT03827408
- Testing
- Midazolam group (MDZ), Dexmedetomidine group (DEX), Combination of Midazolam and Dexmedetomidine (MDZ/DEX)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Nourhan M.Aly
Patient Satisfaction, Bleaching Efficacy
Patient Satisfaction With At-home Dental Bleaching Using Orthodontic Retainers With Different Margin Designs
This randomized single-blind, split-mouth clinical trial evaluated patient satisfaction with at-home dental bleaching using orthodontic retainers with different margin designs, as well as bleaching efficacy, tooth sensitivity…
- Conditions
- Patient Satisfaction, Bleaching Efficacy, Tooth Sensitivity, Gingival Irritation
- Trial name
- NCT07208708
- Testing
- Scalloped margin retainer, Straight orthodontic retainer
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Rey Juan Carlos
Dental Pain
Study of Diclofenac Capsules to Treat Dental Pain
The purpose of this study is to determine whether Diclofenac Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00985439
- Testing
- Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Determination of Beneficial Effect of Using Enamel Matrix Derivative During Implant Treatment
Retrospective Study of Implants With Peri-implantitis Surgically Treated Using Enamel Matrix Derivative (EMD)
The existing records of a private practice limited to the practice of periodontology were reviewed to locate patients who had been diagnosed with peri-implantitis (failing dental implant) and had been surgically treated utilizing…
- Trial name
- NCT05419102
- Testing
- peri-implantitis surgery with enamel matrix derivative
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- North Dallas Dental Health
Dental Caries
Effectiveness of Modified Class IV Atraumatic Restorative Treatment
Atraumatic Restorative Treatment (ART) has become an accepted dental restoration treatment in many developing countries. Because, ART is intended to be operated in molars, and about 10% of all carious lesion by an age of 18 years…
- Trial name
- modARTIV (NCT02234609)
- Testing
- modified ART class IV
- Where
- The Gambia
- Volunteers
- 69 people
- Sponsor
- University of Witten/Herdecke
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