Clinical trials: Dental Treatment
Dental Anxiety, Dental Diseases
Behavioral Support Techniques on Anxiety and Physical Reaction From Dental Treatment
Application of deep touch pressure (DTP) has been suggested to provide positive effects on anxiety modulation. However, empirical and theoretical evidence linked to the clinical effects of DTP is relatively rare in the behavioral…
- Conditions
- Dental Anxiety, Dental Diseases, Dental Trauma
- Trial name
- NCT03819166
- Testing
- with deep touch pressure application, without deep touch pressure application
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dental Caries, Defective Tooth Restorations
Clinical Evaluation of Adhese Universal DC in the Indirect Restorative Therapy
A post market clinical follow up study (PMCF) with Adhese Universal DC is planned to ensure the safety and efficacy of the product. It is a study with two arms.
- Trial name
- NCT04475679
- Testing
- Adhese Universal DC, Adhese Universal
- Where
- Liechtenstein
- Volunteers
- 80 people
- Sponsor
- Ivoclar Vivadent AG
Endodontically-Treated Teeth, Spacing of Anterior Maxillary Teeth
Assessment of Lateral and Vertical Tissue Displacement Obtained by the Retraction Cord and Diode Laser
In fixed prosthodontic treatment, deflection of gingival tissues for diagnosis or making an impression is one of the important phases.
- Conditions
- Endodontically-Treated Teeth, Spacing of Anterior Maxillary Teeth, Broken Teeth Injury With Complication
- Trial name
- NCT04258696
- Testing
- diode laser, ultrapak Knitted retraction cord
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Dental Crowding
Validity of Ashley Howe's Analysis for the Prediction of the Extraction Treatment Decision in Orthodontic Patients at the Permanent Dentition Stage
This study is to evaluate the validity of Ashley Howe's analysis for the prediction of the extraction treatment decision in orthodontic patients at the permanent dentition stage
- Trial name
- NCT07660146
- Testing
- Ashley Howe's Analysis
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Anesthesia
Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects
The purpose of this study is to assess the efficacy and safety of intranasally administered Kovacaine Mist for anesthetizing maxillary teeth in pediatric subjects.
- Trial name
- NCT01701505
- Testing
- 400uL of Kovacaine Mist, 200uL of Kovacaine Mist, 120uL of Kovacaine Mist
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St. Renatus, LLC
Periodontal Diseases, Inflammation Gum
Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes
It is essential that athletes have perfect general health. Oral health plays an important role in this healthy framework necessary so that the results that must be achieved by athletes are not influenced.
- Conditions
- Periodontal Diseases, Inflammation Gum, Caries,Dental
- Trial name
- NCT04251858
- Testing
- Dental Scaling, Oral hygiene instruction
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Metropolitana de Santos
Early Childhood Caries, Dental Caries
Vertical Dimension Changes After Bioflx vs Stainless Steel Crowns in Primary Molars
this randomized controlled trial will compare Bioflx crowns and stainless-steel crowns in children with pulp-treated primary molars.
- Conditions
- Early Childhood Caries, Dental Caries, Pulp-Treated Primary Molars
- Trial name
- BIOFLX-SSC-RCT (NCT07523776)
- Testing
- Bioflx Crown, Stainless Steel Crown
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Cairo University
Endodontically Treated Teeth
Clini Asses of Retentn,Pt Satisfactn and Recurrent Caries of Endocrs Versus Post Crs Using Reinforced Lithium Silicate
Coronal retention of the restoration of RCT teeth is usually compromised, thus intraradicular posts combined or not with core material may be required.
- Trial name
- NCT03713918
- Testing
- Reinforced lithium silicate endocrowns, Post retained reinforced lith silicate crn
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Pulp Capping
Prospective Comparison of Indirect Pulp Therapy and Mineral Trioxide Aggregate Pulpotomy in Decayed Primary Molars
This prospective study compares the use of indirect pulp therapy and mineral trioxide aggregate pulpotomy for pulp therapy of the primary molar with dental caries approaching the pulp.
- Trial name
- NCT02620826
- Testing
- Indirect pulp therapy, Pulpotomy
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Type 2 Diabetes Mellitus (T2DM), Necrotic Pulp
Photodynamic Therapy in Root Canal Treatment of T2DM Patients: Microbiome Analysis Via Next-Gen Sequencing
This clinical study investigates the effectiveness of antimicrobial photodynamic therapy (aPDT) as an additional disinfection method in root canal treatment of patients with Type 2 Diabetes Mellitus (T2DM) who have apical…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Necrotic Pulp, Apical Periodontitis
- Trial name
- NCT06931678
- Testing
- aPDT
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Edentulous Jaws Partially
Stability of Implants With Different Surface Treatment: Randomized Clinical Trial
Objectives: To compare the stability of implant surface treated by dual acid etching (Porous)and implants with anodized surface (Vulcano) over a period of 16 weeks after installation.
- Trial name
- NCT01699568
- Testing
- RFA
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Dental Caries
Stainless Steel Crowns Versus Bulkfill Composite Resin for Restoring Primary Molars After Endodontic Treatment
The pulp therapy in primary teeth is designed to eliminate the infection and keep the tooth in a functional state until its natural exfoliation.
- Trial name
- NCT03186950
- Testing
- Restoration with Stainless Steel Crowns, Restoration using BulkFill CR
- Where
- Brazil
- Volunteers
- 91 people
- Sponsor
- University of Sao Paulo
Pulp and Periapical Tissue Disease, Patients With Pulp Necrosis and Apical Periodontitis
Interleukin 8 and10 Levels Changes in Teeth With Necrotic Pulp and Apical Periodontitis
The goal of this observational study is to evaluate changes in interleukin 8 (IL-8) and interleukin 10 (IL-10) levels in gingival crevicular fluid (GCF) and periapical fluid during root canal treatment in patients with necrotic…
- Trial name
- NCT06713174
- Testing
- Assessment of Interleukin 8 and 10 Level Changes Before and During Root Canal Treatment for Necrotic Pulp with Apical Periodontitis
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Apexification, Apexogenesis
Comparison of Two Dental Techniques Used to Treat Teeth Which Have Become Infected or Painful Following Trauma
Children often damage their front teeth. In approximately 6% of cases, the nerve inside the affected tooth dies (becomes 'non-vital') and natural root development stops.
- Conditions
- Apexification, Apexogenesis, Pulp Necrosis, MTA
- Trial name
- NCT01817413
- Testing
- Mineral trioxide aggregate, Revascularisation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Liverpool
Early Childhood Caries
Happy Teeth for Hopi Tots: Cultural Adaptation of an Oral Health Entertainment-Education Intervention
Tooth decay is a preventable disease occurring at high rates among American Indian (AI) populations. The use of entertaining educational materials and cultural adaptation have shown success in improving health behaviors.
- Trial name
- NCT05297526
- Testing
- Culturally adapted children's book, Standard informational brochure on children's oral health
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northern Arizona University
Carious Lesion, Caries; Initial
Effect of Self-assembly Peptide With or Without Laser on Remineralization of Initial Carious
This study aimed to asses the effect of different remineralizing agents on the initial carious lesions at diff rant after immediately after treatment (as baseline), six months and one year.
- Trial name
- NCT07574814
- Testing
- ER-CR Laser, Without ER-CR Laser
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Delta University for Science and Technology
Anesthesia
Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth in Adults
The purpose of this study is to compare the efficacy of Kovacaine Mist, Tetracaine only, and Placebo for inducing pulpal anesthesia of the maxillary teeth in adults.
- Trial name
- NCT01710787
- Testing
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%, Tetracaine HCl 3%
- Where
- 3 sites in United States
- Volunteers
- 110 people
- Sponsor
- St. Renatus, LLC
Degeneration; Bone
Comparison of a PEG Membrane and a Collagen Membrane for the Treatment of Bone Dehiscence Defects at Bone Level Implants
The aim of the study is to test in a randomized comparative study the performance of Straumann® MembraGel (PEG Membrane) to act as a barrier for guided bone regeneration compared to that of a standard collagen membrane (BioGide®)…
- Trial name
- NCT01012921
- Testing
- barrier membrane, MembraGel, Bio-Gide® membrane
- Where
- 9 sites in Belgium, Germany and 5 more
- Volunteers
- 117 people
- Sponsor
- Institut Straumann AG
HIV Infections
DENTAL CARE OF PATIENTS LIVING WITH HIV
This study is perform to identify oral diseases of people living with HIV (PLWHIV) or co-infected with HBV or HCV.
- Trial name
- DENTA-VIH (NCT05123547)
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Clermont-Ferrand
Edentulous Jaw
The Effect of Implant-supported Prosthesis on Acoustic Voice Quality
The primary aim of this study was to compare the acoustic sound quality of edentulous patients rehabilitated with two-implant overdentures or the all-on-4 concept.
- Trial name
- NCT05692609
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
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