Clinical trials: Dental Treatment
Dental Caries
Comparison of Silver Modified and Conventional Atraumatic Restorative Treatment Modalities
The study is a randomized controlled trial aiming to compare the effectiveness of Silver modified atraumatic restorative technique and (SMART) and conventional atraumatic restorative technique (ART) regarding their caries…
- Trial name
- NCT03881020
- Testing
- Silver diamine Fluoride 38%, Conventional atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Molar Incisor Hypomineralization
Clinical Efficacy of Biomimetic Hydroxyapatite in the Treatment of Molar Incisor Hypomineralization.
The aim of the following study is to evaluate che clinical efficacy of a toothpaste with biomimetic hydroxyapatite for the management of Molar-Incisor Hypomineralization.
- Trial name
- NCT04808180
- Testing
- Biorepair Shock Treatment, No treatment
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Pavia
Oral Health
Maternal Oral Health Educational Intervention to Improve Knowledge, Practice and Dental Service Utilization
This research follows a mixed-method exploratory sequential design. It will take place at the Antenatal and Dental Outpatient Departments (OPD) of Dow University of Health Sciences (Ojha Campus) in Karachi.
- Trial name
- CODE-MOM (NCT07844161)
- Testing
- CODE-MOM
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Endodontically Treated Teeth
Effect of TruNatomy and HyFlex EDM Instrumentation on Postoperative Pain
The aim of the present study is to clinically compare the incidence of postoperative pain after root canal preparation using TruNatomy system and HyFlex Electrical Discharge Machined (EDM) rotary system in asymptomatic necrotic…
- Trial name
- TRN (NCT05289973)
- Testing
- TruNatomy Files, HyFlex EDM Files
- Volunteers
- 36 people
- Sponsor
- Cairo University
Gingivitis and Periodontal Diseases, Dental Plaque
0.2% Chlorhexidine vs MicroRepair ABX in Gingivitis
Gingivitis is the most common form of reversible gum disease, caused by the accumulation of dental plaque. It leads to inflammation of the gums, bleeding, and discomfort, but it can be managed and reversed with professional…
- Conditions
- Gingivitis and Periodontal Diseases, Dental Plaque, Oral Hygiene
- Trial name
- GEM-CHX02 (NCT07088666)
- Testing
- MicroRepair ABX mouthwash, Chlorhexidine 0.2% mouthwash
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Dental Anxiety in Children, Dental Pain
Kaleidoscope Compared to Tell-Show-Do for Reducing Children Pain and Anxiety During Pulp Therapy
The goal of this clinical trial is to investigate if Kaleidoscope glasses help children feel less pain and worry during dental work. It will also explore if these glasses help children feel more comfortable with the dentist.
- Trial name
- NCT07595731
- Testing
- behavior management using Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique and Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique.
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Antibiotics Causing Adverse Effects in Therapeutic Use
Clindamycin Versus Amoxicillin With Clavulanic Acid in Prevention of Early Dental Implants Failure
Among patients receiving dental implants, does the choice of antibiotics reduce the frequency of early implant failure ?
- Trial name
- NCT04980170
- Testing
- Clindamycin 300 mg, Amoxicillin with Clavulanic Acid 635mg
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- Jordan University Hospital
Bone Regeneration
Teriparatide on Maxillary Sinus Floor Osseointegration
The aim of this triple blind randomized controlled trial will be to analyze the effect of a dose of teriparatide combined with a xenograft on bone augmentation of the maxillary sinus, to observe the microarchitecture of the newly…
- Trial name
- NCT06061354
- Testing
- Teriparatide, Maxillary Sinus Augmentation, Dental Implant Installation
- Where
- Chile
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Dental Plaque, Dental Caries
Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse
This study aims to investigate the impact of a bromelain pre-rinse adjunct on oral plaque removal in orthodontic subjects. The study's null hypothesis states that there is no statistically significant difference in visual plaque…
- Trial name
- NCT04512482
- Testing
- Bromelain, Powdered sugar
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Preschool Children, Dental Caries in Primary Teeth
A Comparison of Teledentistry vs Clinical Examination for Treatment Needs Assesment
Dental caries is one of the most common chronic diseases in children and may require complex dental treatment, especially in preschool-aged children.
- Trial name
- NCT07625982
- Testing
- Tele- dentistry intraoral exam
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Premedication
Oral Dexmedetomidine vs Midazoam For Premedication
The aim of this study was to compare the effect of 2 µg/kg of oral dexmedetomidine (DEX) and 0.5 mg/kg dormicum as premedication among children undergoing dental procedures.
- Trial name
- NCT03357718
- Testing
- Precedex, Midazolam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Tooth Extraction Status Nos, Anesthesia, Local
Efficacy and Safety of Administration of Different Doses of 4% Articaine.
The goal of this triple-blind randomized clinical trial is to compare the efficacy and safety of administering one cartridge (1.8 mL) versus two cartridges of articaine 4% with epinephrine 1:100,000 for lower third molar…
- Trial name
- NCT06644950
- Testing
- Efficacy and safety of administering 1 or two cartridges of anesthesia
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Tooth Discoloration, Color Changes During Tooth Formation
Office Bleaching Treatment by Using Rubber-cup and Air-powder Polishing Device Prophylaxis in Rondomised Clinical Design
The increasing demand for whitening teeth necessitates requirements and guidelines to ensure the efficacy of products and bleaching techniques.
- Trial name
- NCT04407910
- Testing
- AIRFLOW® Master device +Opalescence Xtra Boost., rubber-cup+Opalescence Xtra Boost.
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Endodontically Treated Teeth
Influence of Working Length Methods in the Performance of Pulpectomies in Primary Teeth
Verify, through a randomized double-blinded clinical trial, the influence in the performance of pulpectomies in primary teeth, based on two working length methods, electronic and radiographic.
- Trial name
- NCT03161639
- Testing
- Pulpectomies
- Where
- 2 sites in Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Class II Division 1 Malocclusion
Mechanism of Class II Correction With Fixed Lingual Mandibular Growth Modificator (FLMGM)
The aim of the current controlled trial was to assess the possible net skeletal and dental effects of FLMGM treatment in relation to growth with emphasis on the contribution of skeletal and dental changes to sagittal correction…
- Trial name
- FLMGM (NCT01853995)
- Testing
- Fixed Lingual Mandibular Growth Modificator (FLMGM)
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Damascus University
Endodontic Disease, Root Canal Infection
Erbium, Chromium: Yttrium, Scandium, Gallium, Garnet (Er,Cr:YSGG) Laser in Root Canal Disinfection
The purpose of this study is to develop a protocol for biofilms disinfection with a FDA cleared, clinically approved and commercially available Er,Cr:YSGG laser treatments.
- Trial name
- NCT05959629
- Testing
- Waterlase Express™, BIOLASE®, Sodium Hypochlorite
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Molar Incisor Hypomineralization
Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study
MIH is a condition with considerable prevalence in the child population. This structural defect, represented by a change in the color of the enamel, can be accompanied by structural loss and great sensitivity.
- Trial name
- ASHLTDMCS (NCT06330272)
- Testing
- Application of dental mousse based on CPP-ACPF
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Meire Coelho Ferreira
Dental Pulp Diseases, Dental Pulp Necrosis
Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
Non-surgical root canal therapy (RCT) represents a standard of treatment that addresses infected pulp tissue in teeth and protects against future infection while preserving the tooth for the patient for mainly cosmetic purposes.
- Conditions
- Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
- Trial name
- NCT02698163
- Testing
- Nanodiamond reinforced Gutta Percha, Gutta Percha
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, Los Angeles
Periimplantitis, Dental Plaque
Antimicrobial Activity of Two Mouthwashes
This is a three arm randomized trial. The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity.
- Conditions
- Periimplantitis, Dental Plaque, Periodontal Diseases, Caries
- Trial name
- NCT02375178
- Testing
- chlorhexidine, Polyhexamethylene biguanide, Sterile saline solution
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
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