Clinical trials: Dental Treatment
Periapical Periodontitis
Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
The main objective of this study is the prevention and repair of apical periodontitis in lower molars with pulp necrosis after the execution of endodontic treatment in one or two visits in adolescent patients.
- Trial name
- PHAP (NCT01312194)
- Testing
- Root canal therapy in one visit, Root Canal Therapy in two-vist
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Education and Teaching Learning Processes, Psychomotor Skill Learning
Motor Learning Approaches in Periodontal Treatment Education
This study aims to evaluate the effectiveness of different motor learning approaches in preclinical non-surgical periodontal treatment education among dental students.
- Conditions
- Dental Education and Teaching Learning Processes, Psychomotor Skill Learning, Periodontal Education
- Trial name
- MLSPT (NCT07672080)
- Testing
- Implicit Learning With Standard Training, Implicit Learning With Extended Training, Implicit Learning With Distributed Training
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Substance Abuse, Dental Caries
Drug-free Without Toothache. A Study of Free Dental Treatment as a Part of Substance Abuse Treatment
Objectives: The main objective of the study is to investigate 1. How many patients will attend and complete dental care if they are offered it for free during the stay at "The department of substance abuse treatment, University…
- Trial name
- RUST (NCT05606562)
- Testing
- Dental care
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital of North Norway
Autism Spectrum Disorder (ASD
Effectiveness of Clown Therapy in Facilitating Dental Visits for Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in verbal and non-verbal communication and social interaction, as well as repetitive and stereotyped behaviors.
- Trial name
- NCT07906288
- Testing
- Familiarization sessions using clown therapy, Familiarization sessions with conventional methods
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Milan
Dental Anxiety
Dental Anxiety in During Different Dental Treatments (DENANX)
The aim of this observational cross-sectional study is to evaluate the dental anxiety levels of participants aged 18-70 years who will scheduled for different dental treatmentsThe main question it aims to answer is: Does the type…
- Trial name
- DENANX (NCT06485973)
- Testing
- Modified Dental Anxiety Scale (MDAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 322 people
- Sponsor
- Asst. Prof. Dr. Suleyman Emre Meseli
Root Canal Therapy, Endodontically Treated Teeth
Effects of Two Different Physical Therapy Protocols After an Endodontic Intervention
The purpose of this study was to evaluate the clinical results produced by a manual therapy treatment combined with dry needling (MT+DN) and a manual therapy treatment (TM) versus a control (C), to normalize the altered…
- Trial name
- NCT05249686
- Testing
- Manual Therapy + Dry Needling, Manual Therapy
- Where
- Spain
- Volunteers
- 29 people
- Sponsor
- Universidad de Zaragoza
Pain Disorders
Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution
Objectives: The objective of the study was to investigate the bioequivalence between two formulations containing ketoprofen lysine salt (KLS) when administered as single oral doses in two consecutive study periods to healthy male…
- Trial name
- NCT02350296
- Testing
- KSL 40 mg, OKi® 80 mg
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dompé Farmaceutici S.p.A
Dental Pulp Disease, Periapical Diseases
Effect of MTAD on The Outcome of Primary Root Canal Treatment
The aim of this clinical study was to compare the radiographic outcome of a root canal treatment with or without use of MTAD after 24 months recall.
- Conditions
- Dental Pulp Disease, Periapical Diseases, Tooth, Nonvital
- Trial name
- NCT05555563
- Testing
- MTAD irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Post-Dental Gingival Pain, Gingival Swelling
Efficacy and Safety of HA35 Gel for Post-Dental Gingival Pain and Swelling
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of 10% high-concentration 35 kDa hyaluronan (HA35) gel delivered via gel-soaked cotton balls in patients with gingival pain…
- Conditions
- Post-Dental Gingival Pain, Gingival Swelling, Postoperative Oral Pain, Dental Procedure-Related Discomfort
- Trial name
- HA35 (NCT07584655)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Oral Topical Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Dental Veneers, Resin Cements
Adhesive Cementation Materials and Techniques in Aesthetic Dentistry
AIM: To determine the most effective cementation method and resin cement material for long term success of esthetical restorations TASKS: 1.
- Conditions
- Dental Veneers, Resin Cements, Composite Restoration, Orofacial Esthetic Scale
- Trial name
- NCT07491809
- Testing
- Porcelain veneers, Direct composite
- Where
- Latvia
- Volunteers
- 60 people
- Sponsor
- Riga Stradins University
Dental Anxiety
Trial of Pregabalin, Alprazolam, and Placebo in Subjects With Anxiety Prior to Dental Procedure
The primary purpose of the trial is to assess how effective pregabalin, alprazolam, and placebo are at reducing anxiety levels of subjects who take a dose of these treatments 4 hours before a scheduled dental procedure.
- Trial name
- NCT00245609
- Testing
- Pregabalin, Alprazolam
- Where
- 9 sites in Germany, United Kingdom
- Volunteers
- 90 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Dental Caries, Oral Health
Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
Aim: To assess in vivo if the intake of yogurt containing Bifidobacterium animalis ssp. lactis DN- 1173010 probiotic for a period of 2 weeks affects the salivary levels or biofilms of mutans streptococci and the lactobacilli of…
- Trial name
- NCT01657539
- Testing
- Yogurt containing probiotics
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Endodontic Disease, Root Canal Treatment
Impact of an Enhanced Sterile Protocol on Root Canal Treatment Outcome
The main goal of root canal treatment is the removal of existing microorganisms and the prevention of introducing new ones to the root canal system. This will require the application of strict aseptic measures.
- Conditions
- Endodontic Disease, Root Canal Treatment, Root Canal Infection
- Trial name
- NCT03636087
- Testing
- Access cavity preparation, Working Length Determination, Root canal instrumentation and chemo-mechanical preparation
- Where
- United Kingdom
- Volunteers
- 176 people
- Sponsor
- King's College London
Implant Complication, Periimplant Infection
The Effect Of Photobiomodulation On Dental Implant Survival
Dental implants offer a high success rate as the most up-to-date treatment method for replacing lost teeth. However, whilst implants have emerged as the ideal treatment for tooth loss, the incidence of postoperative…
- Conditions
- Implant Complication, Periimplant Infection, Periimplant Bone Loss
- Trial name
- NCT07636265
- Testing
- photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Pain
Pain Management Following Dental Treatment Under General Anesthesia
The main goal of this study is to test the efficacy of postoperative pain management for cases undergoing extractions of primary teeth under GA using a validated measure.
- Trial name
- NCT06574516
- Testing
- Ibuprofen 200 mg, paracetamol
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries in Children
Application of SDF Verses NaF Varnish in Treatment of Carious Primary Teeth
The aim of this study is to assess the postoperative pain after application of silver diamine fluoride versus sodium fluoride varnish in treatment of carious primary teeth.
- Trial name
- NCT03554980
- Testing
- Silver Diamine Fluoride, Sodium Fluoride varnish
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Effect of Topical Application of Clove Gel Versus Benzocaine Gel on Pain Reduction During Application of Simple Dental Procedures in Children.
This study is aimed to evaluate the effectiveness of the topical application of clove gel versus topical application of 20% benzocaine gel in pain reduction in children undergoing dental treatment (rubber dam or matrix band…
- Trial name
- NCT05507359
- Testing
- clove gel, Benzocaine gel
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontically Treated Teeth
Outcome of NSRCT Versus VPT in Management of Teeth with Symptomatic Irreversible Pulpitis Associated with Apical Periodontitis
Pulpitis is the pulpal inflammation in response to irritants which are either microbial, chemical, or physical (mechanical and thermal) in origin.
- Trial name
- NCT06226870
- Testing
- root canal tretment, biodentin VPT, PRF
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Oral Health, Dental Care
Oral Health Recovery Group
The aim of the study is to test a brief, peer-led group-based oral health educational intervention - called the "Oral Health Recovery Group" - designed for individuals with psychiatric disabilities.
- Conditions
- Oral Health, Dental Care, Psychiatric Diagnosis
- Trial name
- NCT05864027
- Testing
- Peer-led Oral Health Recovery Group, Educational Video about Oral Health
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- University of Michigan
Periapical Diseases, Periapical Periodontitis
Postoperative Pain After Conservative Root Canal Preparation
The goal of this clinical trial is to compare the pain experienced by healthy participants after root canal treatment with small versus large root canal sizes. The main questions it aims to answer are: 1.
- Conditions
- Periapical Diseases, Periapical Periodontitis, Postoperative Pain, Pulp Necroses
- Trial name
- NCT06545773
- Testing
- Root Canal Treatment with ProTaper Next Nickel-Titanium File (PTN), Root Canal Treatment withTruNatomy Nickel-Titanium File (TN)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
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