Clinical trials: Dentin Caries
Caries, Dental
Selective Dentine Removal in Primary Teeth
Background There is little information regarding the longevity of the restored tooth, considering the health of the pulp-dentine complex, in children who do not sufficiently cooperate with dental treatment.
- Trial name
- NCT03872037
- Testing
- Selective removal of carious tissue and restoration with Maxxion, Control
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Decayed Primary Molars, Decayed Tooth
Clinical Evaluation of Different Bulk-Fill Restorative Materials in Primary Molars
The goal of this clinical trial is to compare the clinical performance of chemically-cured and light-cured bulk-fill composite materials used for Class II restorations in children aged 4 to 9 years with primary second molars.
- Conditions
- Decayed Primary Molars, Decayed Tooth, Dentin Caries
- Trial name
- NCT07868016
- Testing
- Stela Capsule Bulk Fill Flowable Self-Cure Restorative, Filtek One Bulk Fill Restorative
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Burak Carıkcıoglu
Dental Caries in Children
Silver Diamine Fluoride Gel: Single Group Observational Study
A single group observational study to determine the clinical response of dental caries lesions in primary teeth where 38% silver diamine fluoride gel is applied and cover with 2.5% sodium fluoride varnish.
- Trial name
- KiruPoderoso (NCT05395065)
- Testing
- Silver Diamine Fluoride/Sodium Fluoride Varnish
- Where
- 5 sites in Peru
- Volunteers
- 237 people
- Sponsor
- Advantage Silver Dental Arrest, LLC
Pulp Disease, Dental, Dental Caries
Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide
The aim of this study is to evaluate the effect of application of bioactive glass in different protocols on the formation of dentin bridge after indirect pulp capping using resin composite with its adhesive both are containing…
- Trial name
- NCT04274920
- Testing
- Bioactive Glass, Light cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Caries; Dentin
Clinical Comparison of Composite Materials
Universal adhesive solutions have just entered the market, allowing dentists to choose an adhesive strategy based on the needs of patients and clinical situations.
- Trial name
- NCT06058026
- Testing
- World Dental Federation criteria (FDI)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Recep Tayyip Erdogan University
Caries,Dental, Deep Caries
Comparative Evaluation of an Electrical Impedance Device Versus Digital Radiography in Estimation of Remaining Dentin Thickness
The research question was that in patients with carious posterior permanent teeth, would the electrical impedance device be as valid as digital radiography in estimation of remaining dentin thickness? The proposed hypothesis was…
- Trial name
- NCT06162182
- Testing
- electrical impedance device,, Reference test: Digital Radiographic examination
- Where
- 2 sites in Egypt
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Dental Caries
The Study Aims to Compare the Effectiveness of Mesoporous Bioactive Glass-containing Adhesives vs Conventional Universal Adhesives on the Clinical Performance Composite Restorations Through Promoting Dentin Remineralization After Selective Caries Removal Over a Two-year Follow-up
a two-year, double-blind, randomized controlled trial evaluates the effectiveness of a bioactive glass adhesive (Hi-Bond Universal) versus a conventional adhesive (OptiBond Universal) in Class II carious lesions.
- Trial name
- NCT06990945
- Testing
- Hi-Bond Universal Adhesive, OptiBond Universal Adhesive
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Deep Caries, Dentin Caries
Clinical Investigation of Effectiveness of a Calcium Silicate Cement
The aim of this clinical study is to investigate the clinical performance of a calcium silicate used in the treatment of deep caries lesions.
- Trial name
- NCT06256601
- Testing
- Theracal (calcium silicate), Dycal (calcium hydroxide)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Deep Dentin Caries in Mature Permanent Teeth
Partial Pulpotomy vs Selective Removing in Deep Caries
The aim of this study was to compare the one-year results of selective caries removal and partial pulpotomy treatments in terms of pulp survival and the need for further endodontic treatment in deep carious lesions.Individuals…
- Trial name
- NCT07120009
- Testing
- selective caries removal, partial pulpotpmy
- Volunteers
- 70 people
- Sponsor
- Cukurova University
Indirect Pulp Cap
A Study Comparing Eggshell Based and Gold Standard Materials to Heal Deep Tooth Damage in Adult Molars
This clinical trial will evaluate the effectiveness of eggshell-derived calcium hydroxyapatite compared to calcium hydroxide as indirect pulp capping agent in permanent teeth.
- Trial name
- NCT07183514
- Testing
- eggshell-derived calcium hydroxyapatite, Calcium hydroxide
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- University of Health Sciences Lahore
Dentin Caries
Comparison Of Clinical And Radiological Success Of Pulpotomy Treatments Performed With Proroot MTA, NeoPUTTY MTA, TheraCal PT In Primary Teeth
The goal of this randomized clinical trial is to compare clinical and radiological success rates of NeoPutty MTA, ProRoot MTA and TheraCal PT pulpotomy in 4-10 years old healthy pediatric patients.
- Trial name
- NCT07260357
- Testing
- ProRoot MTA Pulpotomy, NeoPUTTY MTA Pulpotomy, TheraCal PT Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Restoration, Caries; Dentin
Composite Restorations in Primary Molars
The aim of this study was to compare the clinical performance of direct restorations with two different indirect composite systems in primary teeth.
- Conditions
- Restoration, Caries; Dentin, Caries Class Ii
- Trial name
- Composite Rest (NCT07761897)
- Testing
- Fédération Dentaire Internationale (FDI) criteria., survival comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Dental Caries, Secondary Dental Caries
Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars
The aim of this study is to determinate the influence of an alternative adhesive application protocol (i.e. consecutive application of an extra adhesive layer)on restoration longevity in primary molars.
- Trial name
- NCT01680289
- Testing
- Three adhesive coats, Two adhesive coats
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth
A Comparative Clinical Study Assessing Dentin Thickness and Discoloration in Deep Carious Lesions Treated With Biodentine Alone Versus Diode Laser Pre-treatment Followed by Biodentine
This interventional clinical study aims to compare dentin thickness preservation and tooth discoloration in deep carious lesions treated with Biodentine alone versus diode laser pre-treatment followed by Biodentine.
- Conditions
- Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth, Deep Carious Lesion
- Trial name
- NCT07358442
- Testing
- Biodentin, Diode laser
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Misr International University
Dental Caries
Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement
The objective of this randomized clinical trial is to evaluate the survival of restoration with high viscosity glass ionomer cement (HVGIC) with pre-etching with polyacrilic acid compared with no pre-etching in order to treat…
- Trial name
- CEPECO4 (NCT03785769)
- Testing
- HVGIC restoration with pre-etching, HVGIC restoration with non pre-etching
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Dental Caries
Er,Cr:YSGG Laser Versus Conventional Preparation for Minimally Invasive Caries Removal
This study compared two standard methods for minimally invasive caries removal in children: conventional mechanical excavation and Er,Cr:YSGG laser preparation.
- Trial name
- NCT07493278
- Testing
- Mechanical Caries Removal, Er,Cr:YSGG Laser Caries Removal
- Where
- Bulgaria
- Volunteers
- 32 people
- Sponsor
- Medical University of Sofia
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Caries Roots, Flouride Varnish
Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults
Dental caries is a multifactorial, progressive disease which is the major causes of dental pain, infection and tooth loss. Dental caries can substantially compromise the quality of life in older adults 1 2.
- Conditions
- Caries Roots, Flouride Varnish, Caries; Dentin, Caries Arrested
- Trial name
- NCT04255251
- Testing
- Silver Diammine Fluoride, Fluoride Varnishes
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of New England
Dental Caries Extending Into Dentin
Clinical Evaluation of Extensive Direct Composite Restorations With Polyethylene Fiber
The aim of this clinical trial was to compare the clinical performances of composite resin restorations with/without the polyethylene fiber to the first permanent molar teeth with extensively carious pediatric patients.
- Trial name
- NCT04612543
- Testing
- Genial Posterior Composite with Polyethylene Fiber, Genial Posterior Composite
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kafkas University