Clinical trials: Dentinal Hypersensitivity
Dentinal Hypersensitivity
Therapeutic Evaluation of Lower-level Laser for Treating Dentinal Hypersensitivity
The aim of this study was to evaluate the efficacy of low energy laser for the treatment of dentinal hypersensitivity due to periodontal therapy.
- Trial name
- NCT03553290
- Testing
- A.R.C. FOX Laser-FOX Q-810nm, Control
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Dentin Sensitivity
A Clinical Study to Evaluate a Stannous Fluoride Toothpaste for the Relief of Dentinal Hypersensitivity
The purpose of this study is to provide evidence of clinical efficacy of an experimental dentifrice containing stannous fluoride (SnF2) compared to regular fluoride dentifrice in the reduction of dentinal hypersensitivity (DH).
- Trial name
- NCT03310268
- Testing
- 0.454% Stannous fluoride (SnF2) and 0.072% sodium fluoride (NaF): 1450 ppm fluoride in total, 1400 ppm fluoride as sodium monofluorophosphate (SMFP), Stannous Chloride (SnCl2) and 0.15% NaF: 1450 ppm fluoride in total
- Where
- China
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentinal Sensitivity, Hypersensitivity
Pilot Study to Investigate the Efficacy of a Toothpaste in Providing Relief From Dentinal Hypersensitivity
A pilot study to determine the ability of a stannous fluoride containing toothpaste to provide immediate and short term relief from dentine Hypersensitivity compared to a control toothpaste.
- Trial name
- NCT01494649
- Testing
- Test Toothpaste, Negative Control Toothpaste
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity, Dentine Hypersensitivity, Tooth Sensitivity
Comparative Efficacy of Laser Systems and Fluoride in Managing Dentinal Hypersensitivity: RCT
This randomized controlled clinical trial aims to compare the effectiveness of Erbium laser (2940 nm), Diode laser (650 nm), combination Diode laser with fluoride varnish, and fluoride varnish alone in treating dentinal…
- Trial name
- DHLT (NCT07141576)
- Testing
- Erbium laser (2940 nm): Infrared light energy, Diode laser (650 nm): Visible red light energy, Fluoride varnish
- Volunteers
- 96 people
- Sponsor
- Cairo University
Dentin Sensitivity
A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes
This study will determine the effects toothbrush type (power or manual) has on the safety and effectiveness of professional dentinal hypersensitivity treatment with a marketed oxalate-containing solution.
- Trial name
- NCT02513212
- Testing
- Potassium Oxalate, Stannous fluoride paste, Manual toothbrush
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Tooth Sensitivity
An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity
The purpose of the study is to evaluate the efficacy of Sensi-StopTM strips (Procter \& Gamble™) on the relief of dentinal hypersensitivity.
- Trial name
- SSDH (NCT02476032)
- Testing
- Prof applied oxalate, Self applied oxalate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dentin Sensitivity, Dentin Hypersensitivity
Efficacy of a Sonic Toothbrush and 8% Arginine Toothpaste in Reducing Dentinal Hypersensitivity
This clinical study evaluates the efficacy of an oral hygiene regimen consisting of an electric sonic toothbrush used in combination with an 8.0% arginine and calcium carbonate toothpaste in reducing dentinal hypersensitivity…
- Trial name
- NCT07871786
- Testing
- 8.0% Arginine Dentifrice, Electric Sonic Toothbrush, Adult Soft Bristle Manual Toothbrush
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Colgate Palmolive
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
Dentin Sensitivity
A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.
This will be a single center, eight week, randomized, double blind, three treatment arm, parallel design, stratified (by mean baseline Schiff Sensitivity Score of the two selected test teeth) study in healthy participants.
- Trial name
- NCT02651467
- Testing
- Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0), Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
This study will evaluate the effectiveness of an experimental dentifrice containing stannous fluoride, an established dentine tubule occlusion technology, at reducing dentine hypersensitivity (DH) compared to a negative control…
- Trial name
- NCT02861664
- Testing
- Stannous fluoride (SnF2), Sodium monofluorophosphate (SMFP)
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity
This study will investigate the longitudinal efficacy of two experimental oral rinses containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX), formulated at pH 4.5 and pH 7 respectively, for the relief of…
- Trial name
- NCT02542943
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Standard fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity(DH)
This single centre, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a…
- Trial name
- NCT02751450
- Testing
- Stannous Fluoride dentifice, Sodium Monofluorophosphate dentifrice
- Where
- United Kingdom
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Dentifrice in the Relief of Dentinal Hypersensitivity in a Chinese Population
The purpose of this study is to support long-term dentinal hypersensitivity (DH) relief claims of 0.454 percent (%) stannous fluoride (SnF2) containing toothpastes in China.
- Trial name
- NCT04950465
- Testing
- Sensodyne Sensitivity & Gum, Crest Cavity Protection Fresh Lime, Sensodyne Repair and Protect
- Where
- China
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- HALEON
Hypersensitivity
Caries Prevention Products & Dentinal Hypersensitivity
The aim of this pilot research project is to compare the clinical effect on dentinal hypersensitivity of three products: Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) paste with fluoride, 5000 Sodium Fluoride (NaF)…
- Trial name
- NCT02136576
- Testing
- Sensodyne, Crest Cavity Protection & MI Paste Plus, Clinpro 5000
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dentinal Hypersensitivity
Comparison of Efficacy of 5% Fluorocalcium Phosphosilicate Dentifrice and Potassium Nitrate Dentifrice on Dentinal Hypersensitivity
Aim of this study was to assess and compare the efficacy of a dentifrice containing 5% fluoro calcium phosphosilicate and dentifrice containing potassium nitrate on Dentinal Hypersensitivity (DH) compared to a placebo over a…
- Trial name
- NCT03738514
- Testing
- 5% fluorocalcium phosphosilicate dentifrice, 5% potassium nitrate dentifrice
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Hypersensitivity Dentin
Potassium Nitrate Gel and Diode Laser for Dentinal Hypersensitivity
The goal of this randomized clinical trial is to evaluate whether combining a potassium nitrate gel with diode laser therapy is more effective in treating dentinal hypersensitivity compared to using the gel alone.
- Trial name
- NCT06746558
- Testing
- Potassium Nitrate Gel and Diode Laser Therapy, Potassium Nitrate Gel Alone
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- University of Modena and Reggio Emilia
Dentin Sensitivity
To Evaluate the Efficacy of an Experimental Dissolvable Strip in Rapidly Relieving Dentinal Hypersensitivity (DH)
A proof of principle single-centre, randomized-controlled, examiner-blind, two treatment group study to investigate the efficacy of an experimental 15% w/w dissolvable strip in relieving dentine hypersensitivity (DH) after a…
- Trial name
- NCT02937623
- Testing
- Dissolvable polymer strip containing Novamin (calcium sodium phosphosilicate)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Clinical Study of Two Dentinal Hypersensitivity Treatments Used With Normal Oral Hygiene
This study will compare the safety and effectiveness of normal oral hygiene with two different marketed dentifrices, on longer term dentinal hypersensitivity response following use of potassium oxalate desensitizers.
- Trial name
- NCT02221349
- Testing
- Potassium oxalate, Sodium fluoride paste, Stannous fluoride paste
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Sensitivity, Tooth
To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpaste in the Reduction of Dentinal Hypersensitivity.
The objective of this clinical investigation is to assess the efficacy of a toothpaste containing 8% arginine (Colgate-Palmolive Company, New York, NY, USA) as compared to a commercially available non-desensitizing toothpaste…
- Trial name
- NCT07149376
- Testing
- TOMs of Maine Sensitive SLS Free Xtra Fresh, Colgate Cavity protection toothpaste
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
This single centre, dual site, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use
- Trial name
- NCT02612064
- Testing
- Stannous Fluoride dentifice, Sodium Monofluorophosphate dentifrice
- Where
- 2 sites in United Kingdom
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline