Clinical trials: Dentine Caries
Dental Caries in Children
Partial or Complete Excavation of Deep Caries in Primary Molars
Background: The traditional approach of carious lesions with risk for progression has has been to excavate all infected and demineralised tissue before placement of the restoration.
- Trial name
- PBRN (NCT04614285)
- Testing
- Partial excavation
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Dental Caries, Composite Resins
Clinical Evaluation of Dentin Replacement Materials in Posterior Composite Restorations
This randomized controlled clinical trial is designed to clinically evaluate and compare the performance of five dentin replacement materials used beneath posterior composite restorations.
- Conditions
- Dental Caries, Composite Resins, Composite Restoration
- Trial name
- NCT07762651
- Testing
- Biodentine, ACTIVA BioACTIVE, glass ionomer cement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Caries,Dental, Deep Caries
Comparative Evaluation of an Electrical Impedance Device Versus Digital Radiography in Estimation of Remaining Dentin Thickness
The research question was that in patients with carious posterior permanent teeth, would the electrical impedance device be as valid as digital radiography in estimation of remaining dentin thickness? The proposed hypothesis was…
- Trial name
- NCT06162182
- Testing
- electrical impedance device,, Reference test: Digital Radiographic examination
- Where
- 2 sites in Egypt
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Caries Assessment, Caries; Dentin
Evaluation of Radiation-Free Caries Detection Integrated Into Intraoral Scanners Compared With Conventional Diagnostic Methods
The goal of this study is to evaluate if an intraoral scanning device with an integrated radiation-free caries detection tool (near-infrared light) can detect early tooth decay.
- Conditions
- Caries Assessment, Caries; Dentin, Caries; Initial
- Trial name
- NCT07342595
- Testing
- intraoral scan with integrated caries detection tool
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Mehl
Deep Carious Lesions, Partial Caries Removal
This Study Aims to Clinically Assess and Radiographically Measure the Formed Dentin Bridge Over the Pulp, Utilizing Three-dimensional Imaging Following the Application of a Bioactive Restorative System Versus a Conventional Restorative System After Selective Caries Removal to Soft Dentin Over 2
This clinical trial aims to evaluate dentin bridge formation over the pulp following selective caries removal in permanent teeth with deep carious lesions (ICDAS scores 5-6).
- Conditions
- Deep Carious Lesions, Partial Caries Removal, Dentin Bridge
- Trial name
- NCT07171775
- Testing
- Experimental - Bioactive Restorative System, Active Comparator -Conventional Restorative System
- Volunteers
- 66 people
- Sponsor
- Cairo University
Dental Caries
Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement
The objective of this randomized clinical trial is to evaluate the survival of restoration with high viscosity glass ionomer cement (HVGIC) with pre-etching with polyacrilic acid compared with no pre-etching in order to treat…
- Trial name
- CEPECO4 (NCT03785769)
- Testing
- HVGIC restoration with pre-etching, HVGIC restoration with non pre-etching
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Caries, Dental, Tooth Decay
Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations
This is a clinical study evaluating a new dental product called Solventum™ Vitrebond™ Pulp Protect Liner/Base. This new product is designed to be used as a liner or base between the tooth and the dental filling, as well as for a…
- Conditions
- Caries, Dental, Tooth Decay, Dental Decay, Tooth Sensitivity
- Trial name
- NCT07261137
- Testing
- Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Pulp Disease, Dental, Dental Caries
Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide
The aim of this study is to evaluate the effect of application of bioactive glass in different protocols on the formation of dentin bridge after indirect pulp capping using resin composite with its adhesive both are containing…
- Trial name
- NCT04274920
- Testing
- Bioactive Glass, Light cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Deep Carious Lesions
Radiographic Assessment of Calcific Bridge Formation by Light Activated Calcium Silicate Versus Calcium Hydroxide for Deep Caries
sixty participants will be divided in to two groups (n=30) of patient treated by partial caries removal according to the capping material (A),where (A1)represents calcium silicate group,(A2)represent calcium hydroxide group.Apply…
- Trial name
- NCT03233893
- Testing
- light activated calcium silicate
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carious Lesion
Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity
Type of study: Randomized Clinical trial To compare post-restorative sensitivity between titania nanoparticle reinforced bonding agent and bonding agent without nanoparticles in posterior composite restorations.
- Trial name
- NCT05744648
- Testing
- Composite resin restoration using Titania nanoparticle reinforced bonding agent, Composite resin restoration without Titania nanoparticle incorporated bonding agent
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Caries, Dental Diseases
Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars
This research study delves into the effectiveness of bioactive and non-bioactive restorative systems in deep carious permanent molars treated with selective caries removal.
- Conditions
- Dental Caries, Dental Diseases, Deep Caries, Tooth Diseases
- Trial name
- NCT06348953
- Testing
- selective caries removal and conventional non-bioactive restorative system, selective caries removal and bioactive restorative system
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class I Cavities in High Caries Risk, Class I Composite Restorations
The Clinical Performance of Two Dentine Replacement Materials in Deep Occlusal Cavities (Randomized)
Higher mechanical properties are needed to restore structurally compromised posterior teeth, short fiber reinforced resin composite and injectable bioactive resin composites provide superior properties to flowable composites that…
- Conditions
- Class I Cavities in High Caries Risk, Class I Composite Restorations, Randomized Clinical Trial, Occlusal Caries
- Trial name
- NCT06924047
- Testing
- Beautifil Flow Plus X, EverX Flow
- Volunteers
- 50 people
- Sponsor
- Dalia Sameh Fawzi
Dental Caries, Caries; Dentin
The Preformed Metal Crowns Placed Using the Hall Technique Versus the Conventional Restoration
The aim of this study is to compare the survival rate of the conventional restorations with the Hall Technique in carious primary molars.
- Trial name
- NCT04818658
- Testing
- Assessment of the stainless steel crown using the Hall Technique and Compomer Restoration on primary molars
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Deep Carious Lesions
Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after…
- Trial name
- GSE (NCT06780527)
- Testing
- 15% Grape seed extract as dentin pretreatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Dental Caries
Attitude and Practice for Deep Caries Management Between Egyptian and Indian Dentists : a Cross Sectional Study
Study type: Observational Study To assess and compare the attitudes, and practices of dentists in Egypt and India regarding the removal of deep dentin caries and preferred restorative strategies.
- Trial name
- NCT06806254
- Where
- Egypt
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries Arrest
Arresting Active Dentine Lesions and Quality of Life Among a Group of Preschool Children
Testing 3 different caries arresting techniques and the quality of life of a group of preschool children in Mansoura city, Egypt.
- Trial name
- NCT05314660
- Testing
- 38 % silver diamine fluoride, Atraumatic restorative technique, Ultra conservative dentistry
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults.
- Trial name
- NCT06727110
- Testing
- PILP Cement, PILP Conditioner
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Dental Caries, Dentin Sensitivity
Comparative Evaluation of the Post Operative Sensitivity of Cention-N(Commercially Available Restorative Material) Using Conventional and Polymer Bur- In-vivo Study
Cention-N(commercially available restorative material) is a cost effective restoration for posterior restorations. Post-operative sensitivity is of great concern as far as any type of restorative material is concerned.
- Trial name
- NCT05185206
- Testing
- Class 1 cavity preparation using conventional steel bur and restoration with Cention-n(commercially available restorative material)., Class 1 cavity preparation using polymer bur and restoration with Cention-n(commercially available restorative material).
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Decayed Primary Molars, Decayed Tooth
Clinical Evaluation of Different Bulk-Fill Restorative Materials in Primary Molars
The goal of this clinical trial is to compare the clinical performance of chemically-cured and light-cured bulk-fill composite materials used for Class II restorations in children aged 4 to 9 years with primary second molars.
- Conditions
- Decayed Primary Molars, Decayed Tooth, Dentin Caries
- Trial name
- NCT07868016
- Testing
- Stela Capsule Bulk Fill Flowable Self-Cure Restorative, Filtek One Bulk Fill Restorative
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Burak Carıkcıoglu
Pulpitis, Caries; Dentin
The Effect of Cryotherapy on the Outcome of Pulpotomy and Root Canal Treatment
The goal of this randomized clinical trial is to compare the outcome of total amputation and root canal treatment with or without cryotherapy in terms of postoperative pain, quality of life, and treatment success for the…
- Conditions
- Pulpitis, Caries; Dentin, Pain, Postoperative
- Trial name
- NCT06183021
- Testing
- Vital pulp cryotherapy, Intracanal cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Ondokuz Mayıs University