Clinical trials: Dentine Sensitivity
Dentine Hypersensitivity
A Comparative Study On The Effect Of Propolis And Dentine Bonding Agent In Treating Dentine Hypersensitivity
Background: Dentine hypersensitivity (DH) causes considerable pain and discomfort to an individual due to number of stimuli on exposed dentine.
- Trial name
- NCT04754763
- Testing
- Dentin-Bonding Agents, Propolis
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dentin Sensitivity
Effectiveness of a Homecare Dentin Hypersensitivity Gel
Aim: To evaluate the effectiveness of a desensitizing gel for topical and home use in the treatment of dentin hypersensitivity (DH) through a randomized clinical trial, double-blind, with three parallel treatment.
- Trial name
- ECR (NCT02128633)
- Testing
- 5% sodium fluoride, potassium oxalate 5%, strontium chloride 10%, Fluoride neutral NaF gel 2 %
- Where
- Brazil
- Volunteers
- 126 people
- Sponsor
- Universidade Federal de Santa Maria
Dentin Hypersensitivity, Dentin Sensitivity
Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity
Dentin hypersensitivity (DH) can be defined as acute, short-duration pain from open dentin tubules in exposed dentin. The symptom of DH is subjective and varies from patient to patient and may present as mild discomfort or as a…
- Trial name
- NCT04591444
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentine Hypersensitivity
Instant and Lasting Relief Effects of Strontium Chloride/Potassium Nitrate Dentifrice on Dentin Hypersensitivity
The objective of the present study was to compare the effects of a commercially available dentifrice containing 2% strontium chloride and 5% potassium nitrate in a silica base, versus a control dentifrice, containing exactly the…
- Trial name
- NCT01426360
- Testing
- control dentifrice, strontium chloride/potassium nitrate dentifrice
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Sun Yat-sen University
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dentin Hypersensitivity
Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration, Dentin Bonding, and Clinical Durability of Composite Restorations.
This study will investigate the efficacy of three diode laser wavelengths 445 nm, 660 nm, 970 nm when applied just before placement of composite restoration on reducing postoperative sensitivity from Non-carious cervical lesions…
- Trial name
- NCT05501691
- Testing
- 445 nm Diode Laser Wavelength, 660 nm Diode Laser Wavelength, 970 nm Diode Laser Wavelength
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dentin Sensitivity
Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief
The aim of this study is to evaluate the impact of a commercially available desensitizing dentifrice containing 5 percent (%) Calcium sodium phosphosilicate (CSPS) on oral health related quality of life (OHrQoL) in a DH (Dentin…
- Trial name
- NCT07300540
- Testing
- Calcium sodium phosphosilicate (CSPS) Toothpaste
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
A Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity
The aim of this study is to demonstrate the clinical efficacy of the Test Toothpaste containing Calcium Sodium Phosphosilicate (CSPS) in reducing Dentin Hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium…
- Trial name
- NCT07894796
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentine Hypersensitivity
Study to Investigate the Effect of Changes in Dentinal Hypersensitivity on Oral Health Parameters
This exploratory study will investigate the effect of long-term management of Dentine Hypersensitivity (DH) by use of a sensitivity toothpaste on selected oral health parameters, such as changes in oral hygiene (as measured by…
- Trial name
- NCT07768969
- Testing
- Test Toothpaste
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Restoration Failure of Marginal Integrity
Can Flowable Bulk Fill Composites be Used in Proximal Area of Class II Restorations
Treatment clinical trial, randomized, controlled, parallel, double-blinded, with two groups, that aims to evaluate the best application strategy when using a flowable bulk fill composite (Opus Bulk Fill Flow APS, FGM, Brazil) in…
- Trial name
- OPUSFCLASSII (NCT06183320)
- Testing
- Restoration with Incremental Composite in Proximal Wall, Restoration with Bulk Fill Composite in Proximal Wall
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dentine Hypersensitivity
Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
An exploratory study investigating the direct application of potassium nitrate (KNO3) solutions of different concentrations in reducing dentine hypersensitivity.
- Trial name
- NCT01115452
- Testing
- 5% Potassium nitrate, 2.5% Potassium nitrate, Sterile water
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- GlaxoSmithKline
Tooth Bleaching, Dentin Sensitivity
In-office Bleaching Using a Violet Light
The objective of this clinical study is to evaluate the effect of the whitening treatment performed with the violet LED light (405-410 nm), with or without a bleaching gel, on the tooth color changes (immediate and long-term)…
- Trial name
- NCT03207204
- Testing
- 35% Hydrogen peroxide bleaching, 30% Carbamide peroxide bleaching, Violet LED bleaching 1
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tooth Sensitivity, Toothache
Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office Bleaching
Objectives: This study aims to evaluate the effectiveness of preemptive administration of non-steroidal anti-inflammatory Piroxicam-beta-Cyclodextrin on risk and level of tooth sensitivity caused by in-office bleaching procedures…
- Trial name
- NCT03153657
- Testing
- Piroxicam-Beta-Cyclodextrin
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dentin Hypersensitivity
The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.
- Trial name
- NCT04887181
- Testing
- Teethmate Desensitizer, Gluma Desensitizer, Hybrid Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Dentin Hypersensitivity
The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles
Dentin hypersensitivity is one of the most commonly occurring clinical dental conditions which is characterized by short and sharp pain which arises from exposed dentin in response to external stimuli, which typically are…
- Trial name
- NCT06025084
- Testing
- Egg Shell nanoparticles
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Egymedicalpedia
Dentin Sensitivity, Hypersensitivity
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects".
- Conditions
- Dentin Sensitivity, Hypersensitivity, Cervical Lesion
- Trial name
- NCT06463938
- Testing
- Active comparator, Experimental group, Combination of laser and paste
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Tooth Sensitivity
Effect of CPP-ACP Associated With NaF or SnF₂ on Post-Bleaching Tooth Sensitivity
This randomized, triple-blind, placebo-controlled clinical trial aims to evaluate the efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) associated with sodium fluoride (NaF) or stannous fluoride (SnF₂) in…
- Trial name
- NCT07506850
- Testing
- CPP-ACPF, CPP-ACP+SnF2
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity
Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice
The aim of this clinical study is to demonstrate the superior antihypersensitivity efficacy of a novel stannous fluoride (SnF2) and potassium nitrate (KNO3) dentifrice (Investigational Product), compared to SnF2 only, KNO3 only…
- Trial name
- NCT07215767
- Testing
- Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice
- Where
- 3 sites in United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents
The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity.
- Trial name
- NCT06837779
- Testing
- Fluoride Iontophoresis with Acidulated Phosphate Fluoride, Remineralization with sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dentinal Hypersensitivity
Dentinal Hypersensitivity Reduction
The objective of this clinical study is to assess the efficacy of a dentifrice containing stannous fluoride (Colgate-Palmolive Company, New York, NY, USA) as compared to a commercially-available potassium-based toothpaste…
- Trial name
- NCT06244290
- Testing
- Colgate SNF, Sensodyne Extra Whitening, Colgate Fluoride (CDC)
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive