Clinical trials: Denture
Denture Retention
A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting
The purpose of this decentralised study in a real-world setting is to assess the effectiveness of a marketed denture adhesive (Poligrip Power Max Hold + Seal) in preventing food entrapment under dentures (self-assessed).
- Trial name
- NCT07273149
- Testing
- Poligrip Power Max Hold + Seal
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Denture Retention
A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive
The purpose of this study is to investigate the hold properties of an investigational denture adhesive using an established methodology called the maximum incisal bite force (BF), and Kapur-Olshan (KO) index for denture retention…
- Trial name
- NCT04473521
- Testing
- Investigational denture adhesive cream, Super Poligrip Free
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress
In this clinical study, an experimental denture adhesive with a precision tip nozzle was tested to evaluate the relative efficacy to reduce the ingress of food under the denture compared to use of no adhesive or a standard…
- Trial name
- NCT02928380
- Testing
- Experimental Denture Adhesive, Reference (Marketed) Denture Adhesive
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentures
Retention, Stability and Performance Assessment of Denture Fixatives Versus no Fixative Control
This clinical investigation will evaluate the effectiveness, tolerability and safety of two denture fixative creams versus no fixative control
- Trial name
- RESONATE (NCT05689814)
- Testing
- Paraffin based Denture Fixative
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Denture Retention
A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive
The purpose of this study is to investigate the hold properties of two experimental denture adhesives using established maximum incisal BF methodology.
- Trial name
- NCT05173974
- Testing
- Super Poligrip Free, Experimental Denture Adhesive 1, Experimental Denture Adhesive 2
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HALEON
Gum Injury
Assessing Effects of a Denture Gel on Gum Abrasions
This is a parallel design study. Up to 40 subjects with a full mandibular and full maxillary dentures will be enrolled into the study. Subjects will use their current denture care +/- a treatment gel for 4 weeks.
- Trial name
- NCT04913636
- Testing
- Treatment Gel
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Missing Teeth
A Full-Arch Implant- Supported Prosthesis in the Upper and/or Lower Jaw-USA
This study follows subjects who have agreed with their dentist that their failing teeth or missing teeth all need replacing. This study follows their standard routine care with some additional assessments.
- Trial name
- NCT03655990
- Testing
- Treatment with the JUVORA™ Dental Disc
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Juvora Ltd.
Gingivitis
A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
The purpose of this study is to investigate the effectiveness of usage of a range of oral products (toothpaste, mouth rinse, denture cleanser) on the oral health of partial denture wearers compared to existing oral hygiene…
- Trial name
- NCT04290624
- Testing
- Experimental Dentifrice: Stannous Fluoride, COREGA Denture Foaming Cleanser, Mouth rinse: Sodium Fluoride
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- HALEON
Partial Edentulism
Study of Certain Prevail Implants Used to Treat All Types of Edentulism in the Maxilla and Mandible
This observational, prospective clinical study evaluates the performance of the Certain Prevail implant system to show potential crestal bone and soft tissue preservation following the crestal bone.
- Trial name
- PrevailMulti (NCT00728884)
- Where
- Austria
- Volunteers
- 161 people
- Sponsor
- ZimVie
Denture Retention
A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive
The aim of the proposed clinical study is to investigate the efficacy of three experimental denture adhesive creams to improve denture hold over a period of 13 hours.
- Trial name
- NCT07496164
- Testing
- Experimental Denture Adhesive 1, Experimental Denture Adhesive 2, Experimental Denture Adhesive 3
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HALEON
Partial Denture
A Study to Determine the Efficacy of a Denture Adhesive to Seal Out Food Particles From Under the Mandibular Partial Denture
The objective of this study is to evaluate the effectiveness of two denture adhesives at keeping food particles (seeds) from becoming trapped underneath partial denture(s).
- Trial name
- NCT05908890
- Testing
- Experimental Denture Adhesive, Fixodent True Feel Denture Adhesive
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Denture Retention
A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
The purpose of this study is to evaluate a methodology to determine the ability of a denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03345108
- Testing
- Denture Adhesive Cream (Conventional Application), Denture Adhesive (Continuous Strip Application), No Adhesive
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive
The objective of this 4-treatment, 4-period, randomized, crossover, proof of principle bite force study will be to compare bite force measurements over a 12 hour period across two (test) cream denture adhesives, with a currently…
- Trial name
- NCT02937870
- Testing
- Test Product 1, Test Product 2, Reference Product
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Edentulous Mouth
Clinical Evaluation of a New Printable Denture Base Material
This clinical investigation is conducted to prove the long-term clinical performance of a new printable denture base material. The aim of this study is to assess the failure rate, the quality and functionality of the full…
- Trial name
- NCT06458738
- Testing
- Printable denture base material
- Where
- Liechtenstein
- Volunteers
- 22 people
- Sponsor
- Ivoclar Vivadent AG
Peri-implant Mucositis
Efficacy of an Oral Hygiene Implant Protocol
This study is designed to evaluate the effectiveness of cleaning around implants that hold a full denture in the mouth. Different oral hygiene protocols will be compared.
- Trial name
- NCT04462341
- Testing
- Water Flosser, Manual Toothbrush
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Denture Retention
To Evaluate Oral Health and Quality of Life Associated With Use of a Denture Adhesive
The aim of this study is to evaluate the use of a denture adhesive and its ability to demonstrate the improvement in overall gum-health and to improve the oral health related quality of life (OHrQoL) in participants who wear full…
- Trial name
- NCT03807700
- Testing
- Experimental Denture Adhesive
- Where
- Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Mouth, Edentulous
An Observational Clinical Case Series Study to Assess Fit and Quality of Full Dentures Fabricated by AM
This observational clinical case series investigation will be conducted on approximately five (5) enrolled subjects at one (1) site in the US.
- Trial name
- NCT04023006
- Testing
- Removable prostheses
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Edentulous Mouth, Edentulous Jaw
Clinical Outcomes of 3D Printed and Milled Complete Dentures
This is a two-armed, single-center clinical study evaluating performance, efficacy and safety of three dimensional (3D) printed complete dentures and milled complete dentures during a 5-year follow-up period.
- Trial name
- NCT07586774
- Testing
- Lucitone Digital Print, Lucitone Digital Fit
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Mouth, Edentulous
A Descriptive, Prospective Clinical Study to Evaluate Full Dentures Fabricated by Additive Manufacturing
This investigation is undertaken to evaluate the workflow and concomitant products to create full dentures by using Additive Manufacturing (AM) technology, i.e.
- Trial name
- NCT03997604
- Testing
- Full Dentures created by additive manufacturing
- Where
- 2 sites in United States
- Sponsor
- Dentsply International
Denture Cleansers
Frequency of Denture Cleanser Use and Denture Cleanliness
This method development study will be a two treatment arm, randomized, cross over study in a population with edentulous upper arch restored with a maxillary complete denture.
- Trial name
- NCT02780661
- Testing
- Denture Cleanser Daily Use Period, Denture Cleanser Weekly Use Period, Water
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline