Clinical trials: Deprescribing
Eligible Patients Are Aged 65 Years or More Admitted to One of the Five Medicines for Older People Wards, Who Have ACB Score of 3 or More
The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients
The feasibility and acceptability of a collaborative deprescribing intervention to reduce anticholinergic burden among hospitalised older patients
- Trial name
- DART (NCT07599735)
- Testing
- Patients will receive a collaborative deprescribing intervention
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Southampton
Proton Pump Inhibitors, Deprescribing
RAK-PRIDE: Optimizing Proton Pump Inhibitor Use Through Education and Intervention
The goal of this study is to determine if a pharmacist-led educational intervention can reduce the inappropriate use of proton pump inhibitors (PPIs) among adult patients (≥18 years) with potentially inappropriate PPI…
- Conditions
- Proton Pump Inhibitors, Deprescribing, Inappropriate Use
- Trial name
- NCT06858384
- Testing
- Control (Standard treatment), Pharmacist-Led Educational Intervention
- Where
- United Arab Emirates
- Volunteers
- 479 people
- Sponsor
- RAK Medical and Health Sciences University
Anxiety, Insomnia
Remote Yoga Nidra for Deprescribing BZRAs
The overall goal of this application is to assess feasibility and impact of a remotely delivered guided meditation practice called Yoga Nidra, for reducing or stopping use of Benzodiazepine Receptor Agonists (BZRAs) for insomnia…
- Trial name
- NCT06353919
- Testing
- Yoga Nidra, Sleep Hygiene, Anxiety, and Benzodiazepine Receptor Agonist Education
- Volunteers
- 40 people
- Sponsor
- National University of Natural Medicine
Sarcopenia
(De)Prescribing in Hospitalized Sarcopenic Geriatric Patients
The goal of this clinical trial is to compare the effects of a deprescribing pharmacotherapy approach to the STOPP-START approach (usual care) in geriatric patients with sarcopenia and polypharmacy.
- Trial name
- MEDEGESARC (NCT05757765)
- Testing
- deprescribing pharmacotherapy approach (DPA), STOPP-START deprescribing approach (SSA)
- Volunteers
- 160 people
- Sponsor
- Zuyderland Medisch Centrum
Older Adults (60 - 85 Years Old)
The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients
Why this research is important? It is estimated that over one third of all older adults are prescribed medication which are known to have "anticholinergic" side effects.
- Trial name
- DART (NCT07489677)
- Testing
- DART
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Cardiac Amyloidosis, Heart Diseases
N-of-1 for Beta-Blockers in Cardiac Amyloidosis
The study team will generate preliminary data on whether patients with cardiac amyloidosis feel better when their beta-blocker is stopped. To achieve this objective, 20 N-of-1 trials (on vs.
- Conditions
- Cardiac Amyloidosis, Heart Diseases, TTR Cardiac Amyloidosis
- Trial name
- NCT05019027
- Testing
- Beta blocker
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Weill Medical College of Cornell University
Dementia, Potentially Inappropriate Medication Use
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
The overarching goal of this study is to pilot an intervention in which older adults with mild cognitive impairment and dementia and the older adult's care partners are identified in primary care and provided with educational…
- Conditions
- Dementia, Potentially Inappropriate Medication Use, Mild Cognitive Impairment (MCI)
- Trial name
- e-ALIGN (NCT07454824)
- Testing
- e-ALIGN Patient-Portal Deprescribing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University