Clinical trials: Depressed
Depression, Anxiety
Intervention Effectiveness in Improving Psychosocial and Economic Well-being of Sexual Violence Survivors in DRC
The Democratic Republic of the Congo (DRC) has become synonymous with sexual violence by armed groups within the last 2 decades.
- Conditions
- Depression, Anxiety, PTSD
- Trial name
- NCT01385163
- Testing
- Treatment as usual, Voluntary Savings/Loans Assoc, Cognitive Processing Therapy
- Where
- Democratic Republic of the Congo
- Volunteers
- 706 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Major Depressive Disorder (MDD), Gender Differences
Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder
Depression is a common and serious mental health condition that affects mood, thoughts, behavior, and overall quality of life. It arises from a complex interaction of biological, psychological, and environmental factors.
- Conditions
- Major Depressive Disorder (MDD), Gender Differences, Resilience, Psychological, Self Stigma
- Trial name
- GD-GSS-R-S-MDD (NCT07474363)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Eskisehir Osmangazi University
Diabetes, Depression
e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions
Specific Aim 1: To develop a patient-reported, EHR-integrated system to actively monitor the safety and effectiveness of treatment for patients taking FDA-approved medications for one of four common chronic conditions (diabetes…
- Conditions
- Diabetes, Depression, Insomnia, Hypertension
- Trial name
- CEDAR (NCT02087293)
- Testing
- Intervention arm - automated call and phone-based pharmacist counseling
- Where
- United States
- Volunteers
- 38,400 people
- Sponsor
- Brigham and Women's Hospital
Depression
Omega-3 Fatty Acids for Treating Adults With Major Depression
This study will test the effectiveness of two different kinds of omega-3 fatty acid dietary supplements in treating the symptoms of major depression.
- Trial name
- NCT00517036
- Testing
- EPA omega-3 fatty acid, DHA omega-3 fatty acid
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Cedars-Sinai Medical Center
Depression, Hypertension
Biological CVD Risk Factors in Older Depressed Patients
The purpose of this study is to determine if improvements in mood will ameliorate autonomic dysregulation, HPA dysfunction and typical (e.g.
- Conditions
- Depression, Hypertension, Hypercholesterolemia
- Trial name
- NCT00318864
- Testing
- Cognitive behavioral therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depression
COMMIT Depression Trial Nepal
Community health workers (CHWs) have successfully used Motivational Interviewing (MI) to improve treatment adherence (i.e. taking medications and attending clinic appointments) for patients with depression in the US and globally.
- Trial name
- NCT04510909
- Testing
- COMMIT mHealth application
- Where
- Nepal
- Volunteers
- 86 people
- Sponsor
- Possible
Anxiety Disorders, Major Depression
CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care
Background: Common mental illness, such as anxiety disorders and depression, is the main cause for sick leave in Sweden. Cognitive behavior therapy (CBT) has been shown to be effective in alleviating target symptoms of these…
- Conditions
- Anxiety Disorders, Major Depression, Stress Disorders, Primary Insomnia
- Trial name
- NCT01667809
- Testing
- Cognitive behavior therapy, Return to work
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Karolinska Institutet
Anhedonia, Depressed Mood
Depressed Mood and Anhedonia in Healthy Adults
The aim of this study is to evaluate the effect of nutraceutical supplement on depressed mood and anhedonia in volunteers after 8 weeks of consumption.
- Trial name
- MOOD5 (NCT05306093)
- Testing
- Nutraceutical, Maltodextrin
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Pregnancy, Postpartum Depression
Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication
Rosie the Chatbot is an educational chatbot that moms can have on their computers or cellphones and will work by moms typing in their questions about pregnancy, health, infant milestones, and other variety of health related…
- Conditions
- Pregnancy, Postpartum Depression, Infant Development, Infant Conditions
- Trial name
- NCT06053515
- Testing
- Rosie the Chatbot
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Anxiety Disorders, Depression
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol
The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms.
- Conditions
- Anxiety Disorders, Depression, Posttraumatic Stress Disorder
- Trial name
- NCT04912089
- Testing
- COGENT
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of California, San Diego
Lateral Gluteal Depression
Analyze Previously Collected Biopsy Samples From Participants Who Completed the "SPLASH: Split-Body Randomized Clinical Trial of Poly-L-Lactic Acid for Adipogenesis and Volumization of the Hip Dell" Study
Primary Objective: use immunofluorescence (IF) on previously obtained biopsies to analyze and quantify changes in adipose tissue of subjects injected with poly-L-lactic acid (PLLA) or saline.
- Trial name
- NCT06656923
- Testing
- Biopsies
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Pulmonary Resection
Impact of Pulmonary Rehabilitation After Lung Resection for Cancer on Patients' Level of Anxiety and Depression
The interest of pulmonary rehabilitation for patients who underwent lung resection for cancer remains controversial. The investigators studied the effects of the RR and its impact on quality of life and level of anxiety and…
- Trial name
- NCT04985474
- Testing
- questionnaires
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
BIPOLAR DISORDER
Involvement of the Sodium Pump and Endogenous Digitalis-like Compounds in Bipolar Disorder
This study deals with the possible molecular mechanisms that underlie the etiology of bipolar disorders (BD). Previous studies have implicated Na+, K+-ATPase and endogenous digitalis-like compounds (DLC) in the depressive state…
- Trial name
- NA\K-MANIA (NCT01322113)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Postoperative Period, Anxiety
The Effects of Midazolam on the Quality of Postoperative Recovery
The purpose of this study is to determine whether Midazolam given pre-operatively to patients undergoing abdominal surgery improves the quality of recovery.
- Conditions
- Postoperative Period, Anxiety, Fatigue, Depression
- Trial name
- WOLII (NCT01993459)
- Testing
- Midazolam, NaCl (sodium chloride) 0,9%
- Where
- Netherlands
- Volunteers
- 192 people
- Sponsor
- Erasmus Medical Center
Anxiety Disorders, Depression
Process and Outcomes in CBT for Anxious and Depressed Youth
The current study will evaluate the predictors, mediators, outcomes, and critical therapy processes associated with manual-based psychological therapies for 400 youth (ages 7-16 years) with anxiety and/or depression seeking…
- Trial name
- NCT03100279
- Testing
- Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Rutgers University
Anxiety, Depression
Integrated Maternal Psychosocial Assessment to Care Trial (IMPACT) Full Trial
We hypothesize that the intervention will: (1) offer a feasible approach for providing mental healthcare to pregnant women and have a high level of acceptability by pregnant women and healthcare providers; (2) reduce symptoms of…
- Trial name
- NCT01901796
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Loneliness, Mental Health Issue
SSIs for Mental Health and Loneliness
This project includes three studies that explore the effectiveness of brief internet interventions for mental health and loneliness.
- Conditions
- Loneliness, Mental Health Issue, Distress, Emotional, Depression
- Trial name
- NCT05687162
- Testing
- Overcoming Loneliness three-week intervention, Overcoming Loneliness single-session intervention, Single-session "Sharing Feelings" program
- Where
- United States
- Volunteers
- 4,370 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Physical Activity Levels, Cardiovascular Fitness
Effects of Virtual Reality Exercise on Promoting Physical Activity and Health Among College Students
The purpose of this research is to examine the effectiveness of a 4-week immersive-virtual reality (VR) exercise bike intervention on college students' physiological outcomes (physical activity levels, cardiovascular fitness, and…
- Conditions
- Physical Activity Levels, Cardiovascular Fitness, Body Composition, Situational Motivation
- Trial name
- NCT06902727
- Testing
- VR-based exercise bike, Usual routine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Stress Disorders, Post Traumatic, Anxiety
Preventing Post-traumatic Stress in ICU Survivors: A Pilot Randomized Controlled Trial of ICU Diaries
The main objective of the study is to test the feasibility of the ICU diaries intervention in the ICU. The investigators do not have sufficient power to detect differences in the hypotheses below, but will use the present pilot…
- Conditions
- Stress Disorders, Post Traumatic, Anxiety, Depression, Quality of Life
- Trial name
- NCT02067559
- Testing
- ICU Diary, Psychoeducation
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of Manitoba
Bipolar Disorder
Understanding Treatment Adherence Among Individuals With Rapid Cycling Bipolar Disorder
This study will examine how various factors, such as psychiatric symptoms, gender, quality of life, and attitudes toward medication, affect treatment adherence in individuals with rapid cycling bipolar disorder.
- Trial name
- NCT00183703
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Case Western Reserve University
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