Clinical trials: Depressed
Back Pain, Depressive Symptoms
Cannabidiol for Reduction of Brain Neuroinflammation
This study will investigate whether cannabidiol (CBD), the primary centrally and peripherally active non-intoxicating compound in the cannabis plant, exerts anti-neuroinflammatory effects in patients with chronic low back pain…
- Trial name
- CBD (NCT05066308)
- Testing
- CBD
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Depression, Advanced Cancer
Collaborative Care Intervention for Cancer Caregivers
The proposed randomized controlled trial will test the efficacy of a stepped collaborative care intervention, versus enhanced usual care arm, to reduce depression of cancer caregivers.
- Trial name
- NCT02944136
- Testing
- enhanced usual care, stepped collaborative care
- Where
- 2 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Depressive Disorder, Rheumatoid Arthritis
Clinical Study of Escitalopram Oxalate Combined With taVNS in Depression and Concomitant Inflammatory Symptoms
This study is expected to include 90 patients with major depressive disorder and rheumatoid arthritis as study subjects.Randomly divided into 3 groups: drug + VNS stimulation group, drug + sham stimulation group and drug group…
- Trial name
- NCT04037111
- Testing
- Transcutaneous electrical vagus nerve stimulation, drug treatment
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Depression
Behavioral Activation and Emotion-focused Interventions in the Treatment of Depression
The study is a single-case intervention study, evaluating effects of the treatment Behavioral activation and emotion-focused interventions for depression. Research question and hypothesis 1.
- Trial name
- NCT06023732
- Testing
- Behavioral activation and emotion-focused interventions
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Region Stockholm
Depression
Effects of Buprenorphine on Mood in Adults With a Range of Depressive Symptomatology
This study seeks to to study the effects of buprenorphine, a partial mu-opioid agonist, on depressed mood in a healthy young adults with a range of depressive symptomatology.
- Trial name
- BED (NCT02659787)
- Testing
- 0.2mg Buprenorphine
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Bipolar Disorder
Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode
The purpose of this study is to evaluate flexible doses (5-30mg) of aripiprazole versus placebo in patients with bipolar depression.
- Trial name
- NCT00080314
- Testing
- Aripiprazole
- Where
- 28 sites in United States
- Volunteers
- 400 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy Elderly
Effects of Exercise on Depression Symptoms, Physical Function, and Quality of Life in Community-Dwelling Elderly
The purpose of this study was to investigate the effects of 8-week exercise training on depression symptoms, physical functions, and quality of life in the community-dwelling elderly.
- Trial name
- NCT00931814
- Testing
- exercise training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Early Skin-to-skin Contact, Psychological Distress
Effects of the Couplet Care in Neonatal Intensive Care Unit
This is a quasi-experimental before and after intervention study taking place in the level III NICU of Turku University Hospital in Finland to evaluate the effects of the Couplet Care, a care model which provides maternal and…
- Conditions
- Early Skin-to-skin Contact, Psychological Distress, Parenting, Preterm Infant
- Trial name
- NCT05655104
- Testing
- Couplet Care
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Treatment Resistant Depression (TRD), Chronic Pain
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
The goal of this clinical trial is to understand the effect of ketamine on the brain in people with treatment-resistant depression (TRD).
- Trial name
- NCT07247006
- Testing
- Ketamine hydrochloride injection
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Major Depressive Disorder
Measuring Psychomotor Response to L-DOPA Challenge As a Biomarker for Outcomes in Late-Life Depression: a Pilot Feasibility Trial
Background Adults over the age of 60 with symptoms of major depressive disorder are said to have late-life depression (LLD), a condition that usually decreases a person's quality of life and is associated with other risks like…
- Trial name
- LLDOPA (NCT06626152)
- Testing
- Apo-levocarb
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Bipolar Disorder, Depression
Disseminating Evidence-based Mood Disorder Chronic Care Models
This study will determine if a version of the chronic care model for individuals with mood disorders can improve patient health.
- Trial name
- NCT01615458
- Testing
- Chronic Care Model for Mood Disorders
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Major Depressive Disorder
Wellness Monitoring for Major Depressive Disorder
The Wellness Monitoring for Major Depressive Disorder (MDD) study is a prospective, longitudinal, observational study aimed at identifying biomarkers of relapse in MDD.
- Trial name
- CBN-Well (NCT02934334)
- Testing
- Observational
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Sidney Kennedy
Post Traumatic Stress Disorder, Smoking
Computerized Tailored Intervention for Behavioral Sequelae of PTSD in Veterans
This project assesses the usability and feasibility of a multi-behavioral computerized, tailored intervention (CTI) or expert system delivered via the Internet for veterans with Post-Traumatic Stress symptoms.
- Conditions
- Post Traumatic Stress Disorder, Smoking, Anxiety, Depression
- Trial name
- CTI-PTSD (NCT01510834)
- Testing
- Multibehavioral, Computerized Tailored Intervention STR2IVE
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Pacific Islands Health Care System
Stress, Psychological, Stress, Physiological
Family-centered Mental Health Promotion Intervention
Goal: The long-term goal of the proposed research program is to test the effectiveness of a preventative behavioral intervention and to scale it up for use with broader immigrant populations to reduce stress and mental health…
- Conditions
- Stress, Psychological, Stress, Physiological, Anxiety, Depression
- Trial name
- NCT04453709
- Testing
- Problem Management Plus for Immigrants at family settings, Talk program with Community Support Service Pamphlet (CSS)
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Major Depressive Disorder, Insomnia
Brain Mechanisms and Targeting Insomnia in Major Depression
Preliminary studies suggest that the response to antidepressant medication can be accelerated by targeting insomnia with adjunctive use of eszopiclone.
- Trial name
- NCT00628914
- Testing
- escitalopram and eszopiclone, Escitalopram
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Depression, Elderly
Collaborative Care for Depressed Elderly in Korea
Late-life depression is associated with physical limitations, greater functional impairment, increased utilization and cost of health care, and suicide.
- Conditions
- Depression, Elderly, Korean, Collaborative Care
- Trial name
- NCT01626716
- Testing
- care management
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- National Clinical Research Coordination Center, Seoul, Korea
Depression - Major Depressive Disorder
Association of Beta Blocker Use with Depressive Outcomes
An Observational Study to Explore the Association Between β-Blocker Use and Depressive Outcomes
- Trial name
- NCT06743633
- Volunteers
- 1,136 people
- Sponsor
- Chitkara University
Depression, Post-Partum, Massage
Investigation of the Effect of Massage Application on Functional Status and Depression in Postpartum Mothers
Postpartum depression is a condition with high morbidity in mothers and negatively affects all family relationships. It has been observed that depression in the mother at only 2 months of age negatively affects the relationship…
- Conditions
- Depression, Post-Partum, Massage, Functional Status
- Trial name
- NCT06539858
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Depression in Remission
A Study of SDI-118 in Participants in Remission From Depression
This is a multi-center, double-blind, randomized, placebo-controlled study to determine the safety, tolerability, and pharmacodynamics of SDI-118 in a once daily (QD) dosing regimen on male and female study participants reporting…
- Trial name
- NCT05212116
- Testing
- SDI-118
- Where
- 3 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Syndesi Therapeutics
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.