Clinical trials: Depressed
Heart Rate Variability
Impact of Community-Based Biofeedback Program on Drug Use and Mental Health Among People Experiencing Homelessness
The purpose of this randomized controlled trial was to compare the effectiveness of an HRV-BF intervention versus a health promotion active control intervention focused on improving mental health symptoms among people…
- Trial name
- HRV-BF (NCT05897580)
- Testing
- Heart Rate Variability - Biofeedback (HRV-BF), Health Promotion (HP)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of California, Irvine
Emotional Well-being
iCBT to Promote Emotional Well-being in University and Research Communities: Feasibility and Acceptability Study
This study will evaluate a brief internet-based cognitive behavioral therapy (iCBT) program developed specifically for university students, researchers, and academic staff.
- Trial name
- iCBT-Academia (NCT07082296)
- Testing
- iCBT-Academia
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Joaquim Radua
Major Depression Severe
Ayahuasca and Esketamine for Major Depression
Double-blind, randomized trial comparing 4 weekly doses of oral ayahuasca and esketamine in patients with major depression.
- Trial name
- NCT07212946
- Testing
- Ayahuasca, Esketamine
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo
Depression, Late Life Mood Disorder
A Study on Better Cognitive Functioning Through Braintraining on the Internet
This study evaluates the efficacy of an eight-week online cognitive training program on feasability and on objective and subjective cognitive functions in patients with late life mood disorders (LLMD).
- Conditions
- Depression, Late Life Mood Disorder, Impaired Cognition, Alteration in Mood
- Trial name
- BrainFit (NCT04006756)
- Testing
- Online cognitive training 1, Online cognitive training 2
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Amsterdam UMC, location VUmc
Depression
PEERS Using Peer Mentors to Deliver Depression Care
Fifteen to twenty percent of older Americans (6 to 8 million people) suffer from depression but more than one-half do not receive any services, a burden disproportionately shared by low-income and minority older adults who…
- Trial name
- NCT04319094
- Testing
- PEERS, Social interaction
- Where
- 2 sites in United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Mental Health Wellness 1, Depression
Examining the Feasibility of a Mobile Mental Health Application in Psychotherapy
There is an urgent need to better understand and manage the mental health burden among working adults. Up to 40% of persons with serious mental illnesses do not receive care or stop intervention programs due to negative stigma.
- Trial name
- NCT04200170
- Testing
- Rose
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Ask Rose
Major Depressive Disorder, Soft Tissue Discomfort Syndrome
Functional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort Syndrome
The objective of this study is to determine the time course of duloxetine efficacy on the symptoms of Major Depressive Disorder (MDD)and on the symptoms of Soft Tissue Discomfort Syndrome(STDS) via use of 24-hour Actigraph™…
- Conditions
- Major Depressive Disorder, Soft Tissue Discomfort Syndrome, Pain
- Trial name
- NCT01035073
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pennsylvania
Depression, Anxiety
Mechanisms of Anxiety and Depression Study
Eligible participants will come in for three separate visits in which they will be interviewed, perform a variety of tasks, and undergo a non-invasive MRI scan.
- Trial name
- NCT03135756
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Palo Alto University
Depression, Anxiety
A Pychoeducational Intervention for Women With Diabetes
This proposal describes a small randomized study to determine whether usual medical care (UMC) for diabetes combined with a psychoeducational program is more effective than UMC for diabetes alone.
- Conditions
- Depression, Anxiety, Anger
- Trial name
- SWEEP (NCT01185561)
- Testing
- Psychoeducational intervention
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Loyola University
Depression
Homecare Agency-Randomized Trial of Web Implementation Strategy for Depression
To identify effective implementation strategies that can efficiently promote the use of evidence-based practices (EBP) across a large number of geographically dispersed, independent Home Health Agencies (HHAs).
- Trial name
- NCT02206386
- Testing
- MHTraining-Net, Enhanced Support
- Where
- United States
- Volunteers
- 7,800 people
- Sponsor
- Weill Medical College of Cornell University
PreDiabetes, Physical Inactivity
The Effect of Exercise on Quality of Life, Sleep Quality and Anxiety in Patients With Prediabetes (EFEXQULS)
The aim of this study is to determine the effect of exercise on quality of life, sleep quality and anxiety in patients with prediabetes.
- Conditions
- PreDiabetes, Physical Inactivity, Quality of Life, Sleep
- Trial name
- EFEXQULS (NCT05147883)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
TMS Protocols in the Treatment of PD
Standardization and Optimization of TMS Protocols for the Treatment of PD With Depression or Cognitive Impairment
The goal of this study is to determine whether transcranial magnetic stimulation (TMS) is an effective treatment in Parkinson's disease patients with depression or cognitive impairment.
- Trial name
- NCT03552861
- Testing
- repetitive transcranial magnetic stimulation(rTMS)
- Where
- 10 sites in China
- Volunteers
- 252 people
- Sponsor
- Guangdong Provincial People's Hospital
Postoperative Pain, Postpartum Depression
Dose Low Dose Ketamine in Casesarian
The results of ketamine, ketamine and midazolom can be copied after birth in cesareans subjected to spinal anesthesia.
- Trial name
- ketamine (NCT06237569)
- Testing
- Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
Alzheimer s Disease, Dementia
CommunityRx-Dementia + Peer Navigation (CRxDpeer)
The CRxDpeer intervention, delivered by a trained peer navigator, in practice called a "peer mentor", includes three evidence-based components: (a) focused education about common social (e.g., food and housing insecurity) and…
- Conditions
- Alzheimer s Disease, Dementia, Caregiver, Loneliness
- Trial name
- CRxDpeer (NCT07346183)
- Testing
- CommunityRx-Dpeer
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Bipolar Disorder
Radiosurgical Neuromodulation for Refractory Depression
This study is designed to evaluate the safety and effectiveness of an investigational procedure for treating people with treatment resistant bipolar depression (TRD).
- Trial name
- NCT01403441
- Testing
- Radiosurgical Neuromodulation using the Cyberknife
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Depression, Sleep Disturbance
Smart Light Therapy Glasses for Sleep and Mental Wellness
A pair of smart light therapy glasses (Lumos Glasses) was engineered to control the amount of blue light exposure at a person's eyes through a battery powered light source and nano-coating that reflect blue light.
- Trial name
- NCT07168954
- Testing
- Lumos Glasses
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Opioid-use Disorder, Addiction
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
- Trial name
- CLARO (NCT04559893)
- Testing
- Collaborative Care
- Where
- 16 sites in United States
- Volunteers
- 729 people
- Sponsor
- RAND
Depression, Anxiety
T.E.A.M. Feasibility and Efficacy Study 2.0
T.E.A.M. psychotherapy was developed by one of the founders of cognitive therapy, David Burns and builds on traditional CBT with an emphasis on T = Testing, E = Empathy, A = Agenda Setting (assessing and building motivation) and…
- Trial name
- TEAM (NCT03694106)
- Testing
- TEAM PSYCHOTHERAPY
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Feeling Good Institute
Depression
To Demonstrate the Relative Bioequivalency of Comparing Single 100 mg Doses Of Cord's 50 mg Desipramine HCL Tablets To Merrell Dow's 50 mg Norpramin Tablets
To demonstrate the relative bioequivalency of comparing single 100 mg doses Of Cord's 50 mg Desipramine Hcl tablets to Merrell Dow's 50 mg Norpramin tablets.
- Trial name
- NCT00914004
- Testing
- Desipramine HCl 50 mg Tablets Cord Laboratories, Norpramin 50 mg Tablets Merrell Dow Pharmaceuticals, Inc
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sandoz
Spinal Cord Injuries
SCI-VIP: Predictive Outcome Model Over Time for Employment (PrOMOTE)
This study will be an extension of the Spinal Cord Injury Vocational Integration Program (SCI-VIP). The study involves research about how to help Veterans with spinal cord injury (SCI) gain employment.
- Trial name
- PrOMOTE (NCT01141647)
- Testing
- Vocational Rehabilitation
- Where
- 7 sites in United States
- Volunteers
- 1,047 people
- Sponsor
- VA Office of Research and Development
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