Clinical trials: Depressed
Adapted Physical Activity and Cancer
Adapted Physical Activity in a Chemotherapy Ambulatory Care Unit: Feasibility and Impact on Fatigue, Anxiety and Depression in Cancer Patients
Physical activity has demonstrated efficacy in cancer prevention and improves quality of life and outcome in cancer survivors. Patients undergoing chemotherapy, especially those with advanced disease, may have symptoms leading to…
- Trial name
- UMACHAPA (NCT03049436)
- Testing
- Program of adapted physical activity
- Where
- France
- Volunteers
- 250 people
- Sponsor
- CHU de Reims
Major Depressive Disorder
Major Depressive Disorder With Mixed Features - Extension
Lurasidone HCl is a compound that is a candidate for the treatment of major depressive with mixed features.This clinical study is designed to test how well Lurasidone works to treat major depressive disorder with mixed features…
- Trial name
- RESOLVE3 (NCT01423253)
- Testing
- Lurasidone
- Where
- 17 sites in United States
- Volunteers
- 48 people
- Sponsor
- Sumitomo Pharma America, Inc.
Major Depressive Disorder, Breast Cancer
Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast Cancer
Cancer and depression commonly occur together, and each worsens the other. We conducted a large psychotherapy study treating depression in breast cancer patients, showing that psychotherapy lowers symptoms.
- Conditions
- Major Depressive Disorder, Breast Cancer, Venlafaxine
- Trial name
- IPT (NCT04973930)
- Testing
- Interpersonal Psychotherapy, Venlafaxine HCl ER
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York State Psychiatric Institute
Cancer
Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
RATIONALE: Ketamine hydrochloride may lessen neuropathic pain in patients with cancer. It is not yet known whether ketamine hydrochloride given together with the best pain management is more effective than a placebo given…
- Trial name
- NCT01316744
- Testing
- ketamine hydrochloride, pharmacogenomic studies, questionnaire administration
- Where
- 3 sites in United Kingdom
- Volunteers
- 214 people
- Sponsor
- University of Glasgow
Quality of Life, Post ICU Discharge
Study in Intensive Care Follow-up Programme in Improving Long-term Outcomes of ICU Survivors
Study Hypothesis: Critical illness is associated with long-term medical and psychological sequelae that can impact the professional and private life.
- Trial name
- SUIVI-REA (NCT01796509)
- Testing
- Medical, psychological, social
- Where
- France
- Volunteers
- 545 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Internet-Delivered Cognitive Behavioural Therapy, Depression
Optimizing a Wellbeing Program for Care-partners of Those With SCI
Spinal cord injuries (SCI) have a devastating effect not only on individuals incurring the life changing event, but also on those who are involved in their care.
- Conditions
- Internet-Delivered Cognitive Behavioural Therapy, Depression, Anxiety, Spinal Cord Injuries
- Trial name
- NCT06318832
- Testing
- ICBT
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anxiety, Depressive Symptoms
StriveWeekly: Self-Guided Online Intervention for Anxiety, Depression, and Stress in University Students
This study was a randomized controlled trial of an original online mental health promotion program. This study aimed to: 1) establish program effectiveness by examining symptom change between conditions and 2) examine predictors…
- Conditions
- Anxiety, Depressive Symptoms, Stress, Psychological
- Trial name
- NCT04361045
- Testing
- StriveWeekly
- Where
- United States
- Volunteers
- 1,631 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV Infections
Quality of Life, Depression and Sexual Function in Men Living With HIV
This observational case-control study evaluates quality of life, depressive symptoms, and sexual function in heterosexual men living with HIV who are receiving effective combination antiretroviral therapy and have achieved…
- Trial name
- NCT07376239
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Depression
Single-Dose Pharmacokinetics (PK) Study of Novel Neurogenic Compound NSI-189
This is a subject single blinded, randomized, placebo-controlled, single dose, first-time-in-human study with three or more ascending cohorts.
- Trial name
- NCT01310881
- Testing
- NSI-189 Phosphate
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Neuralstem Inc.
Bipolar Depression
Multiple Treatment Study Using Low Field Magnetic Stimulation for Bipolar Depression
Objectives: To demonstrate the duration of the antidepressant effect of Low Field Magnetic Stimulation (LFMS)in subjects with bipolar depression.
- Trial name
- LFMS (NCT01929681)
- Testing
- Low Field Magnetic Stimulation
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Mclean Hospital
Anxiety, Depression
Culturally Adapting CBT for Chinese Youth in Ontario
This mixed methods study proposes a culturally adapted cognitive behavioural therapy (CA-CBT) model for a Chinese demographic in Canada.
- Trial name
- NCT03711344
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder, Treatment-Resistant Depression
Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD Patients
In this double-blind, randomized, sham-controlled trial, the investigators aimed to examine the effect of accelerated piTBS on suicide risk in a group of treatment-resistant patients with MDD (i.e., TRD), using an extensive…
- Conditions
- Major Depressive Disorder, Treatment-Resistant Depression, Suicide Ideations
- Trial name
- NCT06372834
- Testing
- piTBS being delivered using the Magstim Rapid2 stimulator
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Child Mental Disorder, Anxiety Disorders
Youth Metacognitive Therapy Feasibility Trial
One in eight children and young people (CYP) suffer mental health problems needing support or treatment and 5% have more than one such problem.
- Conditions
- Child Mental Disorder, Anxiety Disorders, Depression
- Trial name
- YoMETA (NCT05260060)
- Testing
- Treatment as usual: Control, Group Metacognitive Therapy (Group-MCT): Experimental
- Where
- United Kingdom
- Volunteers
- 95 people
- Sponsor
- University of Manchester
Postpartum Depression, Emotional Regulation
Prenatal Affective Cognitive Training to Reduce the Risk of Postpartum Depression (PACT)
Many pregnant women face the risk of experiencing depression after giving birth, especially if they've previously dealt with depression.
- Conditions
- Postpartum Depression, Emotional Regulation, Cognitive Function 1, Social, Pregnancy Related
- Trial name
- PACT (NCT06046456)
- Testing
- Prenatal Affective CogntiiveTraining
- Where
- Denmark
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Parkinson Disease
The Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Depression in PD
This study is a double blind comparative study examining the effectiveness of the transcutaneous auricular vagus nerve stimulation treatment on Parkinson's disease patients with depression.
- Trial name
- PD-D-taVNS (NCT07679529)
- Testing
- Active Transcutaneous auricular vagus nerve stimulation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Mental Health Wellness 1
Emotional Intelligence Program for Adolescents With Antisocial Behavior (DYNAMIS)
This study assessed the effectiveness of an emotional intelligence program based on the Salovey and Mayer model among adolescents exhibiting antisocial behavior.
- Trial name
- DYNAMIS (NCT06124183)
- Testing
- The program comprises 12 sessions and additional activities to be carried out after each session, alongside counseling from the program's leading professionals
- Where
- Colombia
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness
Social Prescribing for a Mindful Lifestyle
The goal of this clinical trial is to evaluate the effectiveness of an 8-week mindfulness lifestyle social prescribing program in community-dwelling older adults aged 55 and older.
- Conditions
- Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness, Social Isolation
- Trial name
- NCT07669805
- Testing
- Mindfulness Lifestyle Social Prescribing Program
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Major Depression
Safety, Tolerability and Efficacy of the Transdermal System in Elderly Subjects With Major Depression
Objective of this 16-week, open-label study is to assess the safety and tolerability of once daily application of three doses of STS during continuous dosing in the treatment of elderly subjects with major depression.
- Trial name
- NCT00285766
- Testing
- Selegiline Transdermal System
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- Somerset Pharmaceuticals
Depression, Fatigue
Programs To Support You During Chemotherapy
This randomized pilot trial studies how well two supportive programs work for improving fatigue and depressive symptoms in patients with GI undergoing chemotherapy.
- Conditions
- Depression, Fatigue, Stage IIA Colorectal Cancer, Stage IIB Colorectal Cancer
- Trial name
- PRO-YOU (NCT02489422)
- Testing
- Laboratory Biomarker Analysis, Questionnaire Administration, Daily Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Major Depressive Disorder (MDD)
Transcranial Magnetic Stimulation in Depression.
Major depressive disorder (MDD) has increased in recent years, affecting 16.1% of the adult population nationwide. Currently, there are pharmacological and psychological treatments that have a 67% remission rate for depressive…
- Trial name
- LiTMS (NCT07638202)
- Testing
- The experimental group(A) received conventional drug treatment combined with Li-TMS., control group B were administered standard drug therapy with coil placement, without exposure to Li-TMS emission.
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
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