Clinical trials: Depressed
Stress, Emotional, Stress-related Mental Disorders
Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences
The study aims to examine the effectiveness of joint parent-adolescent intervention in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as measured by the…
- Conditions
- Stress, Emotional, Stress-related Mental Disorders, Adverse Childhood Experiences
- Trial name
- EASY-PEP (NCT06619821)
- Testing
- Emotiaonl skill enhancement, PCE promotion, Psychoeducation
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Suicidal Ideation, Suicide, Attempted
iTBS+D-Cycloserine for Youth Suicide
Background and Rationale: Suicide is the second leading cause of death in Canadian Emerging Adults (EAs; 18-24yrs). Current treatments for suicidal thoughts and behaviors are limited and novel treatments are required to save…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Depression, Anxiety
- Trial name
- NCT06121284
- Testing
- D-Cycloserine, intermittent Theta-Burst-repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Calgary
Depression
Safety and Antidepressant Effects of Rellidep in Major Depressive Disorder
The investigators hypothesize that Rellidep will be effective in improving the symptoms of major depression. The available evidence strongly suggests that Rellidep contains a mood altering ingredient or ingredients.
- Trial name
- NCT00446719
- Testing
- Rellidep
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Mount Sinai Hospital, Canada
Major Depression
Individual Narratives of Stimulation (ECT and TMS)
Electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are two evidence-based treatments for major depressive disorder.
- Trial name
- INSight (NCT07807930)
- Testing
- There is no intervention in this observation study (qualitative interviews about past treatment experiences)
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Nottingham
Nasal Congestion and Inflammations, Sinus Congestion Chronic
Effects of SinuSonic on Psychological and Physical Well-Being
The goal of this clinical trial is to evaluate the effects of using the SinuSonic on psychological and physical well-being in adults who have nasal/sinus congestion.
- Trial name
- NCT06268730
- Testing
- SinuSonic
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depression, Cancer
Omega 3 FA Supplements as Augmentation in the Treatment of Depression
To assess the efficacy of Omega 3 Fatty acid (Omega 3 FA) augmentation of desvenlafaxine (DVS) compared to placebo augmentation of DVS when used to treat depression and anxiety symptoms in patients with select medical conditions…
- Conditions
- Major Depression, Cancer, Diabetes, Cardiovascular Diseases
- Trial name
- NCT01803711
- Testing
- Desvenlafaxine, Omega 3 Fatty acids
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- UConn Health
Chronic Disease
Effects of Tele-yoga in Long-term Conditions
Long-term illness is common in the Swedish population, especially among older people. These conditions are often associated with impaired quality of life due to high physical and psychological symptom-burden.
- Trial name
- TELEYOGA (NCT03703609)
- Testing
- Tele-yoga
- Where
- 4 sites in Sweden
- Volunteers
- 311 people
- Sponsor
- Linkoeping University
Pelvic Pain, Depression
Psychosocial Treatment for Women With Depression and Pain
Patients with depression and pain have poorer outcomes in response to depression treatments than depressed patients without pain.
- Trial name
- NCT00895999
- Testing
- Interpersonal Therapy for Pain (IPT-P), Enhanced Support and Connection to Counseling
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Psychological Distress, Anxiety
Psychological Symptoms in Cardiac and Pulmonary Diseases
The European guidelines emphasize the importance of conducting psychological screenings to investigate the presence of stress and symptoms of anxiety and depression in patients with cardiovascular disease: depression, common…
- Conditions
- Psychological Distress, Anxiety, Depression, Cardiovascular Diseases
- Trial name
- NCT06396793
- Testing
- no intervention because it is an observational study
- Where
- Italy
- Volunteers
- 421 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Depressive Symptoms, Fatigue
Programs to Support You During Chemotherapy (Pro-You)
This randomized pilot clinical trial studies Yoga Skills Training or attention control in reducing fatigue and depressive symptoms during chemotherapy in patients with stage II-IV colorectal cancer.
- Conditions
- Depressive Symptoms, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Stage IIA Colon Cancer
- Trial name
- Pro-You (NCT02148406)
- Testing
- Yoga Skills Training (YST), questionnaire administration, fatigue and depressive symptom assessment and management
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Infertility, Male, Depression
Impact of Duloxetine on Male Fertility
The investigators are conducting a placebo-controlled, randomized control trial with duloxetine in healthy, fertile men not previously on any antidepressants.
- Trial name
- NCT03038867
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Unipolar Depression
Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression
This study will evaluate the effectiveness of paroxetine versus interpersonal psychotherapy and a combination of the two in helping elderly patients with depression remain well and improve quality of their lives.
- Trial name
- NCT00178100
- Testing
- Interpersonal Psychotherapy, paroxetine
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of Pittsburgh
Asymptomatic Condition, Neck Pain
Accessory Movements and Associated Factors During Active Cervical Range of Motion
This project aims to quantify accessory movements that occur during cervical range of motion (ROM) assessment in young adults and to examine their relationship with functional and psychological factors.
- Trial name
- NCT07267507
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Atılım University
Depression
Measuring Quality of Decisions About Treatment of Depression
The purpose of this randomized controlled trial is to examine the impact of a patient decision aid on the quality of decisions about managing symptoms of depression.
- Trial name
- NCT01152307
- Testing
- DVD/Booklet: Coping with Symptoms of Depression
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- University of Massachusetts, Boston
Bipolar Disorder
Riluzole to Treat Depression in Bipolar Disorder
This study examines if Riluzole, FDA approved for ALS, will improve symptoms of depression in Bipolar Disorder. Purpose: This study will examine the safety and effectiveness of riluzole (Rilutek trademark) for short-term…
- Trial name
- NCT00054704
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Institute of Mental Health (NIMH)
Apathy, Stroke
Transcranial Direct Current Stimulation (tDCS) in Chronic Post-Stroke Apathy
The purpose of this study is to test the efficacy and safety of tDCS (Transcranial Direct Current Stimulation) on apathy in stroke patients.
- Trial name
- TDCS-PSA (NCT02915484)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stony Brook University
Postpartum Depression, Heart Rate Variability
Vitamin B6 and Depression in Pregnant and Peri-partum Women
Perinatal depression is a highly prevalent and serious health issue during pregnancy. According to statistics, approximately one out of every ten postpartum women experiences this condition.
- Trial name
- NCT06445933
- Testing
- Vitamin B6
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Depressive Symptoms, Mild Traumatic Brain Injury
rTMS for Military TBI-related Depression
The purpose of this study is to investigate the efficacy, safety, and tolerability of two dorsolateral prefrontal cortex (DLPFC) repetitive transcranial magnetic stimulation (rTMS) protocols to alleviate symptoms of depression in…
- Conditions
- Depressive Symptoms, Mild Traumatic Brain Injury, Concussion
- Trial name
- ADEPT (NCT05426967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 3 sites in United States
- Volunteers
- 198 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Infertility, Distress, Emotional
Testing an Evidence-Based Self-Help Program for Infertility-Related Distress in Women
Now affecting one in six couples in Canada, infertility is defined as a lack of conception after 12 or more months of regular, unprotected sexual intercourse.
- Conditions
- Infertility, Distress, Emotional, Mental Health Issue
- Trial name
- NCT06006936
- Testing
- Coping with Infertility Self-Help Program
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- University of Regina
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