Clinical trials: Depressed
Fatigue
Sleep and Training Aspects in Dialysis Fatigue - Exercise Intervention
The purpose of the current study is to investigate whether changes in patients' sleep quality and quantity will be followed by improvements in parameters related to physical and mental fatigue in patients receiving hemodialysis…
- Trial name
- StandFirm (NCT01721551)
- Testing
- Exercise, Usual Treatment
- Where
- 3 sites in Greece
- Volunteers
- 50 people
- Sponsor
- University of Thessaly
Depression
Neural Mechanisms With CES in Depression
This study will examine the effect of cranial electrotherapy stimulation (CES) treatment on adults with depression. Scalp based electroencephalogram (EEG) will be utilized to record the brain activity of participants whilst they…
- Trial name
- NCT04587531
- Testing
- Cranial Electrotherapy Stimulation
- Where
- United Kingdom
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Electromedical Products International, Inc.
Depression, Epilepsy
Effect of Vagal Nerve Stimulation on Gastric Motor Functions
The specific aim of this study is to compare simultaneous assessment of gastric emptying and gastric accommodation in response to a caloric meal In patients who have previously undergone activation of left cervical VNS for the…
- Trial name
- NCT06038929
- Testing
- Vagal nerve stimulant
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Mayo Clinic
Major Depressive Disorder
Riluzole Augmentation Pilot in Depression (RAPID) Trial
The investigators are doing a research study to find out if riluzole, when taken along with a standard antidepressant (sertraline) can help people with major depression.
- Trial name
- RAPID (NCT01703039)
- Testing
- Riluzole, Sertraline
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy Volunteers, Depression
Neurobiology of Suicide
Background: There are no good treatments for people considering suicide. Researchers want to study suicide with questions, blood tests, brain imaging, and sleep studies.
- Trial name
- NCT02543983
- Testing
- Magnetic Resonance Imaging scanner, 3T, NeurOptics PLRTM-3000 Pupillometer, Experimental Anxiety Devices
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Childhood Anxiety, Childhood Depression
Anxiety Among Children: Adaptation and Effectiveness of the Program Super Skills for Life in School Settings
Super Skills for Life (SSL) is a transdiagnostic prevention program designed for children with anxiety and depressive symptoms based on cognitive-behavioral therapy.
- Conditions
- Childhood Anxiety, Childhood Depression, Low Self-Esteem, Quality of Life (QOL)
- Trial name
- NCT07162402
- Testing
- Super Skills for Life (SSL) Program, No Active Intervention
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Fatima Jinnah Women University
Depression, Postpartum
The Effect of Yoga Applied to Primiparous Pregnant Women on Postpartum Depression and Maternal Attachment
This randomized controlled trial aims to evaluate the effects of an 8-week prenatal yoga intervention on postpartum depression and maternal attachment among primiparous pregnant women.
- Trial name
- NCT07583095
- Testing
- prenatal yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Muş Alparslan University
Treatment Resistant Depression
Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)
The primary objective of this study is to assess the long-term efficacy of psilocybin with respect to use of new antidepressant treatment, hospitalisations for depression, suicidality, and depressive severity rated using the…
- Trial name
- NCT04519957
- Where
- 8 sites in United States, Czechia and 3 more
- Volunteers
- 66 people
- Sponsor
- COMPASS Pathways
Emotion Regulation, Depression
JoyPop Mobile Mental Health App With Post-Secondary Students
Students within post-secondary education settings are experiencing increasing stress, distress, and mental health difficulties. Many post-secondary education settings have identified student mental health and wellbeing as a…
- Conditions
- Emotion Regulation, Depression, Anxiety, Stress
- Trial name
- NCT06154369
- Testing
- JoyPop
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Late-life Depression, Treatment-resistant Depression
SSM vs HEP in Late-Life Depression
The investigators will conduct a randomized controlled trial (RCT), comparing SSM (n=96) versus HEP (n=96) in 192 LLD participants stratified by site and presence of treatment resistant late life depression (TR-LLD).
- Trial name
- NCT03564041
- Testing
- Sahaj Samadhi Meditation (SSM), Health Enhancement Program (HEP)
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Treatment-Resistant Depression
Efficacy and Safety of TAK-653 in Treatment-Resistant Depression
The purpose of this study is to evaluate the efficacy of TAK-653 compared with placebo in maintaining the effect of ketamine treatment on depressive symptoms.
- Trial name
- NCT03312894
- Testing
- TAK-653
- Sponsor
- Millennium Pharmaceuticals, Inc.
Postpartum Depression, Melatonin
Postpartum Depression
Our aim was to diagnose and initiate early treatment for postpartum depression by detecting the changes of melatonin levels in c-sections with different antesthesia modalities.
- Trial name
- NCT04278456
- Testing
- postpartum depression
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Erzincan University
Bipolar Disorder
Cytidine and Omega-3 Fatty Acids in Bipolar Disorder
The goal of the proposed clinical trial is to assess the effect of oral cytidine and omega-3 fatty acids (O3FA) on bipolar disorder symptoms.
- Trial name
- NCT00854737
- Testing
- cytidine, omega-3 fatty acids
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Mclean Hospital
MDD
Take-home Functional Electrical Stimulation for MDD
The purpose of this study is to learn whether Functional Electrical Stimulation (FES) of the facial muscles is effective in treating major depressive disorder (MDD) and to develop a model for take-home delivery.
- Trial name
- NCT06261177
- Testing
- Functional Electrical Stimulation (FES)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Child Abuse, Sexual
Optimal Treatment Strategies for Sexually Abused Children
This study will determine the necessity of including abuse-focused interventions in the treatment of sexually abused children.
- Trial name
- NCT00073684
- Testing
- Trauma focused cognitive behavioral therapy (TF-CBT), Brief abuse-focused treatment, Brief coping skills treatment
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Rowan University
Depression
Effectiveness of a Crowdsourced Cognitive Reappraisal Intervention
This study evaluates a web-based, crowdsourcing platform to promote cognitive reappraisal. Half of participants will be granted access to the crowdsourced reappraisal platform.
- Trial name
- NCT02302248
- Testing
- Crowdsourcing reappraisal intervention, Expressive writing intervention
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Alcohol Use Disorder, Depression
aTBS for Treatment of Depression in AUD
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for improvement of depressive symptoms and drinking behavior in individuals with alcohol dependence.
- Trial name
- NCT03981185
- Testing
- Accelerated theta burst treatment
- Sponsor
- Stanford University
Bipolar Disorder (BD), Bipolar Disorder Depression
Time Restricted Eating (TRE) in Bipolar Disorder
This is a randomized controlled trial investigating the effects of an 8-TRE intervention compared to a wait list (control) on metabolic health and body composition in people diagnosed with BD and who are currently obese and at…
- Conditions
- Bipolar Disorder (BD), Bipolar Disorder Depression, Overweight (BMI > 30)
- Trial name
- TREBD (NCT07211217)
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Mental Health Issue, Depression
Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders
US residents who have mental health issues sign the informed consent form and are screened and enrolled for this study. Participants complete a survey upon enrollment and are randomized into one of two study arms.
- Conditions
- Mental Health Issue, Depression, Anxiety
- Trial name
- NCT06502717
- Testing
- VIOME Precision Nutrition Program
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Viome
Stress, Anxiety
Yoga for Mental Health in Parkinson's Patients
This study is a waitlisted randomized controlled trial. We aim to assess the level of compliance for those learning the intervention and to evaluate the impact of the practice on neuropsychological and somatic outcomes using…
- Conditions
- Stress, Anxiety, Depression, Parkinson Disease
- Trial name
- NCT05335850
- Testing
- Isha Kriya, Nadi Shuddhi, Nada Yoga
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
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