Clinical trials: Depressed
Anxiety, Depression
VA Home-Based Emotional Learning With Practical Skills
The purpose of this study is to determine the feasibility and acceptability of providing evidence-based, person-centered, culturally tailored treatment for anxiety and/or depression via telephone to rural Veterans receiving…
- Trial name
- VA-HELPS (NCT01685528)
- Testing
- CBT
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Baylor College of Medicine
Perinatal Depression, Postpartum Depression
Development, Feasibility and Acceptability of Fathers and Babies (FAB): A Pilot Study
During this project the investigators will develop and pilot test a companion intervention for fathers (Fathers and Babies-FAB), to supplement the Mothers and Babies Course (MB) that provides stress and mood management tools for…
- Conditions
- Perinatal Depression, Postpartum Depression, Depression
- Trial name
- NCT03427528
- Testing
- Fathers and Babies (FAB), MB 1-on-1 plus TXT
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Major Depressive Disorder
Effects of Duloxetine vs. Escitalopram on Heart Rate Variability in Depression
Low heart rate variability is a marker of increased risk of cardiac mortality, and is observed in depressed coronary artery disease patients. Some antidepressants may themselves, however, decrease heart rate variability.
- Trial name
- NCT00215228
- Testing
- duloxetine vs. escitalopram
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Chronic Kidney Disease Stage 5
Quality of Life and Depression in Dialysis Patients
The aim of this study is to evaluate quality of life (QOL) and depression in peritoneal dialysis patients compare to hemodialysis patients and assess hydration effect on QOL and depression over time.
- Trial name
- QOLD (NCT01668628)
- Where
- South Korea
- Volunteers
- 1,068 people
- Sponsor
- Fresenius Medical Care Korea
Treatment Resistant Depression
Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine
This study aims to assess the efficacy and safety of intranasal esketamine as maintenance antidepressant therapy in patients who have demonstrated clinical improvement with off-label intravenous racemic ketamine for…
- Trial name
- NCT04856124
- Testing
- Intranasal esketamine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Psych Atlanta
Chronic Pain, Anxiety
Nu-V3 Non-Invasive Nerve Stimulation Device Trial for Chronic Pain, Anxiety, Depression, Sleeplessness
The Nu-V3 Clinical Study is a prospective, single-arm, open-label, multi-center study using the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3 (NCT05335980)
- Testing
- Nu-V3
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nu-Life Solutions
Depression
Intern Health Study
Retrospective studies have established a strong correlation between reports of life stress and depression. Investigators have begun to further explore this relationship by examining the role of gene x stress interactions in the…
- Trial name
- NCT01809080
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Treatment Resistant Depression
D-cycloserine for Relapse Prevention Following Intravenous Ketamine in Treatment-resistant Depression
This is a two-stage experiment; the first stage is an open label trial in which participants receive six intravenous (IV) treatments of ketamine. The second stage includes participants that responded to ketamine (i.e.
- Trial name
- NCT02772211
- Testing
- Ketamine, D-cycloserine
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Major Depressive Disorder
IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL)
This study tests the efficacy of interpersonal psychotherapy (IPT) for major depression following perinatal loss (early and late fetal death and early neonatal death) in a sample of 274 women in Flint and Detroit, Michigan.
- Trial name
- HeAL (NCT04629599)
- Testing
- Interpersonal psychotherapy for major depression following perinatal loss, Coping with Depression
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- Michigan State University
Hemodialysis, Interpersonal Psychotherapy
Interpersonal Psychotherapy-Based Counseling for Hemodialysis Patients: Effect on Adjustment and Depression
The aim of this clinical study is to examine the effect of interpersonal psychotherapy-based counseling on adjustment to illness and depression levels in individuals receiving hemodialysis treatment.
- Trial name
- NCT06839287
- Testing
- Interpersonal psychotherapy-based counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Baskent University
Hunger, Depression
Carbohydrate Rich Drink Reduces Pre-endoscopic Discomfort for Patients Going for Elective Endoscopic Procedures
The study is a randomised controlled trial that aims to evaluate whether carbohydrate loading pre-endoscopy can improve patients' overall satisfaction and is not associated with negative impact on endoscopic quality or increased…
- Conditions
- Hunger, Depression, Anxiety, Vomiting
- Trial name
- NCT05342116
- Testing
- Nestle Preload, Water
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Anxiety, Depression
Child STEPS for Youth Mental Health in Maine Sustainability
The overarching goal of this project is to study the sustainability of MATCH-ADTC within community mental health clinics, to learn what is needed for evidence-based practices (EBPs) to take root and thrive within a public system.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112304
- Testing
- MATCH-ADTC, TRAC
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Harvard University
Major Depressive Disorder
Biomarkers for Outcomes In Late-life Depression (BOLD)
Major depressive disorder (MDD) is a common psychiatric illness with high cost to society and individual patients. One reason for the high cost is that most patients endure lengthy and ultimately unsuccessful empiric…
- Trial name
- BOLD (NCT01082237)
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Musculoskeletal Diseases, Depression
Physical Activity Levels and Musculoskeletal Health Among Health Science Academicians at Istanbul Aydin University
This study aims to investigate the relationship between physical activity levels and posture, sleep quality, depression, and musculoskeletal system problems among academic staff working in the health sciences field at Istanbul…
- Conditions
- Musculoskeletal Diseases, Depression, Sleep Wake Disorders, Posture
- Trial name
- PA-ACAD-IAU (NCT07445100)
- Testing
- Observational Data Collection
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Pulmonary Disease, Chronic Obstructive
Chronic Obstructive Pulmonary Disease (COPD)-Related Outcomes and Costs for Patients on Combination Fluticasone Propionate-Salmeterol Xinafoate 250/50mcg Versus Anticholinergics in a COPD-Comorbid Depression/Anxiety Population
The objective of this study was to examine COPD-related outcomes for patients with comorbid depression/anxiety who are on combination fluticasone propionate/salmeterol xinafoate compared to those receiving anticholinergics.
- Trial name
- NCT01337336
- Testing
- fluticasone propionate/salmeterol xinafoate, Anticholinergics
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Major Depressive Disorder
The Neurobiology of Approach Avoidance Training in Depression
The purpose of this study is to test the effects of a computerized approach/avoidance training (AAT) procedure on behavioral, affective, and brain mechanisms that are important for reward sensitivity and well-being in individuals…
- Trial name
- ACTIV8 (NCT02330744)
- Testing
- Approach-positive AAT, Control AAT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Bone Neoplasms, Soft Tissue Neoplasms
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue.
- Conditions
- Bone Neoplasms, Soft Tissue Neoplasms, Anxiety, Stress, Psychological
- Trial name
- BIOPSY-STRESS (NCT07727434)
- Testing
- Routine Diagnostic and Treatment Pathway
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Major Depressive Disorder
Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Levomilnacipran ER fixed doses versus placebo in the treatment of outpatients with major depressive disorder.
- Trial name
- NCT00969709
- Testing
- Levomilnacipran ER
- Where
- 38 sites in United States
- Volunteers
- 724 people
- Sponsor
- Forest Laboratories
TBI (Traumatic Brain Injury), Headache
Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches
This study will assess the combined effectiveness of repetitive transcranial magnetic stimulation (rTMS) and telehealth based therapy in helping manage mild traumatic brain injury (mTBI) related headaches.
- Conditions
- TBI (Traumatic Brain Injury), Headache, Depression
- Trial name
- NCT05176392
- Testing
- Active rTMS, Headache Management Therapy, Headache Education Control
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Veterans Medical Research Foundation
Depression, Anxiety
Effect of Music Therapy in Medical Students (EMTMS)
Mental health has become an increasingly pressing concern, especially since the onset of the COVID-19 pandemic. However, not all individuals experiencing mental suboptimal states require pharmacological treatment.
- Conditions
- Depression, Anxiety, Insomnia
- Trial name
- NCT05949736
- Testing
- The Online intervention platform
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
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