Clinical trials: Depressed
Postpartum Depression
A Study to Evaluate Efficacy and Safety of SAGE-547 in Participants With Severe Postpartum Depression (547-PPD-202B)
The purpose of this study was to determine if SAGE-547 Injection infused intravenously at up to 90 micrograms per kilogram per hour (μg/kg/h) for 60 hours reduces depressive symptoms in participants with severe postpartum…
- Trial name
- NCT02942004
- Testing
- SAGE-547 60 μg/kg/h, SAGE-547 90 μg/kg/h
- Where
- 32 sites in United States
- Volunteers
- 138 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Major Depressive Disorder, Psychotic Disorders
Safety Study of ORG 34517 for Major Depression With Psychotic Features
Patients suffering from Major Depressive Disorder with Psychotic features who have received no changes in their medications in the previous two weeks will receive "usual" treatment of antidepressants, antipsychotics and/or mood…
- Trial name
- NCT00226278
- Testing
- ORG 34517
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Depression, Anxiety
Sea Swimming for Treatment of Depression and Anxiety
There is a developing evidence to suggest that open cold water swimming could have an impact on depression and anxiety: anecdotal reports of benefits to mental wellbeing as a result of regular open water bathing research…
- Trial name
- NCT04528485
- Testing
- Sea swimming
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Devon Partnership NHS Trust
Depression
Inflammation-Induced CNS Glutamate Changes in Depression
Increased inflammation has been implicated in the pathophysiology of a number of neuropsychiatric illnesses including mood disorders, which affect almost 30 million adults in the United States alone.
- Trial name
- NCT03004443
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Depression
Citalopram vs Clomipramine vs Placebo in Recurrent Depression
citalopram and clomipramine are better than placebo in preventing new episodes of depression in patients with recurrent depression
- Trial name
- NCT01575158
- Testing
- Citalopram, Clomipramine
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Perceived Stress, Depression
Online Yoga for Improving the Well-being of Desk-based Workers
The goal of this clinical trial is to evaluate the effectiveness of an 8-week online yoga intervention in improving the well-being and productivity of desk-based workers.
- Conditions
- Perceived Stress, Depression, Anxiety, Mindfulness
- Trial name
- NCT06289426
- Testing
- Yoga
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kingston University
Anxiety, Depression
Pushing Limits - Adventure: Pilot Study
Team building exercises have been shown to be effective in improving an individual's ability to work within a group and build working relationships with others.
- Trial name
- NCT02290678
- Testing
- Adventure-based Programming
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Obesity
Relationship of Exercise Capacity With Physical Activity Level, Sleep Apnea Risk and Quality of Life in Obese Adults
Volunteer female and male individuals aged 20-65 years, followed in the State Hospital Internal Diseases Unit, diagnosed with obesity (BMI> 30 kg/m^2), and meeting the inclusion criteria will be included in the study.
- Trial name
- NCT05088317
- Testing
- Exercise capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Goksen Kuran Aslan
Cancer
Psychoeducation for Anxiety, Depression, Cognitive Avoidance, and Sense of Coherence in Women With Cancer
This study evaluates the effectiveness of a structured psychoeducational intervention on anxiety, depression, cognitive avoidance, and sense of coherence in women with cancer.
- Trial name
- NCT07837440
- Testing
- Structured Psychoeducational Intervention
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Ardakan University
Trauma, Depression
FAmily Oriented Mindfulness Informed Legal Education (FAMiLE) Programme for Parent or Carers Affected by Incarceration and Improving Parenting in Nigeria
Incarceration is a prevalent problem globally and in Nigeria. Its effect significantly impacts left behind parent or primary care givers and also the wellbeing of the families and children.
- Conditions
- Trauma, Depression, Anxiety, Parenting Intervention
- Trial name
- FAMiLE (NCT06628518)
- Testing
- FAmily oriented Mindfulness informed Legal Education (FAMiLE)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Teesside University
Bipolar Disorder
Treatment Study of Bipolar Depression
The purpose of this study is to determine whether a single intravenous administration of an N-methyl-D-aspartate antagonist is safe and effective for the acute treatment of bipolar depression.
- Trial name
- NCT00947791
- Testing
- ketamine, midazolam
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obsessive-compulsive Disorder, Ocd
Riluzole Augmentation in Treatment-refractory Obsessive-compulsive Disorder
Obsessive-compulsive disorder (OCD) affects 2-3% of the population and leads to a great deal of suffering. Many patients benefit from established treatments, the mainstay of which are cognitive behavioral therapy and a group of…
- Trial name
- NCT00523718
- Testing
- riluzole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Sleepiness, Daytime
Effects of Litebook EDGE™ Phototherapy on Academic Performance and Brain Activity
As children pass through puberty the timing of their sleep-wake cycle shifts and they experience a strong urge to stay up and awaken late.
- Trial name
- LiteBook (NCT05383690)
- Testing
- LED bright light treatment device
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Temporal Interference Stimulation, Non Suicidal Self Injury
TIS for NSSI in Adolescent Depression
Temporal Interference Stimulation (TIS) has been successfully used to help patients with depression. However, its role in alleviating self injuries remained uncertain.
- Conditions
- Temporal Interference Stimulation, Non Suicidal Self Injury, Major Depressive Disorder
- Trial name
- NCT07554755
- Testing
- Active Temporal Interference Stimulation (TIS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Hospital of Anhui Medical University
Health Services for the Aged, Frailty
e-GAB: Electronic Geriatric Assessment Bundle: Development of an Arabic Self-administered Android CGA Application
The aim of this study is to design and assess the accuracy of administering the electronic Geriatric Assessment Bundle (e-GAB) compared to geriatrician performed comprehensive geriatric assessment (CGA) in a group of Egyptian…
- Conditions
- Health Services for the Aged, Frailty, Cognitive Impairment, Depression
- Trial name
- NCT04211285
- Testing
- e-GAB, standard physician performed CGA
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anxiety, Depression
The Effects of Animal Assisted Therapy in Outpatient Psychiatry Clinics
This study will examine whether a session of animal-assisted therapy reduces anxiety levels and improves long-term clinical outcomes of outpatient psychiatric patients in regard to their Generalized Anxiety Disorder (GAD-7)…
- Conditions
- Anxiety, Depression, Psychiatric or Mood Diseases or Conditions
- Trial name
- NCT05326074
- Testing
- Animal assisted therapy cohort
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Depression / Major Depressive Disorder
Longitudinal Effects of Brain Stimulation on Decision-Making and Reward Learning
This study investigates the longitudinal effects of brain stimulation treatments on decision-making and reward learning. Here, daily assessments of reinforcement learning behavior are used in patients with depression who receive…
- Trial name
- NCT07823218
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Bonn
Breast Cancer
Design and Evaluation of the Effects of a Physical Therapy Program With Digital Support in Patients With Breast Cancer
Breast cancer surgery usually results in reduced range of motion of the shoulder joint, weakness of the musculature and altered scapular kinematics during movement.
- Trial name
- NCT04837248
- Testing
- Active Comparator: Group 1. Conventional treatment, Experimental: Group 2. Experimental treatment.
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Treatment Resistant Depression
Linear Asymmetric rTMS in Adolescent Treatment-Resistant Depression: Tolerability of Treatment Durations Ranging From Ten Days to One Day
This is a pilot interventional study to investigate the acceptability, tolerability, and side effect profile for varying numbers of treatment sessions/day of a new rTMS treatment in adolescents with treatment-resistant depression…
- Trial name
- NCT03986658
- Testing
- Linear Asymmetric rTMS System
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- NeuroQore Inc.
Major Depressive Disorder
Appalachian Mind Health Initiative
We propose to carry out a treatment experiment in which we evaluate the extent to which randomizing primary care clinicians have access to remote internet-based Cognitive Behavior Therapy (eCBT) in rural West Virginia (WV) and…
- Trial name
- AMHI (NCT04120285)
- Testing
- remote internet-based cognitive behavior therapy (eCBT)
- Where
- 7 sites in United States
- Volunteers
- 1,280 people
- Sponsor
- University of South Florida
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