Clinical trials: Depressed
Pregnancy Related, Mental Health Issue
MamaConecta: Digital Tool for Maternal Mental Health
The goal of this randomized controlled trial is to validate a digital health tool, Dana app, that enhances well-being and supports mental health monitoring for women during the perinatal period.
- Conditions
- Pregnancy Related, Mental Health Issue, Postpartum Depression, Postpartum Anxiety
- Trial name
- DDT (NCT06442774)
- Testing
- Mobile application, Monitoring via wearable
- Where
- 3 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- A Thousand Colibris, S.L
Depressive Symptoms, Nutrition, Healthy
Mind Nutrition Study. Effectiveness of Improving Nutrition on Depressive Symptoms and Work Ability
The goal of this randomized, controlled trial is to examine the effectiveness of dietary counseling on depressive symptoms, work ability, and quality of life in mental health and substance abuse professionals.
- Conditions
- Depressive Symptoms, Nutrition, Healthy, Quality of Life, Eating Behavior
- Trial name
- NCT06448117
- Testing
- Mind Nutrition
- Where
- Finland
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Satakunta University of Applied Sciences
Caregivers
Mobile Technology and Data Analytics to Identify Real-time Predictors of Caregiver Well-Being
The purpose of this study is to test whether personalized messages from an easy-to-use mobile app improve mood and stress among care partners and to see if care partners like using the app.
- Trial name
- NCT04556591
- Testing
- Just-in-time adaptive intervention (JITAI), Control
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Treatment Resistant Depression (TRD)
Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
This study is being conducted at Massachusetts General Hospital (MGH) to explore whether adding psychedelic coaching can enhance the effects of ketamine or esketamine maintenance treatment in individuals with treatment-resistant…
- Trial name
- NCT07563868
- Testing
- Psychedelic Integration Coaching
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder
A Study of Xiongdan Wan Treating Depression
This is a prospective, single-arm, open-label study to evaluate the safety and efficacy of Xiongdan Wan monotherapy in patients with Major Depressive Disorder(MDD), conducted in Shang Hai Mental Health Center.
- Trial name
- NCT05136365
- Testing
- Xiongdan Wan
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Perimenopausal Depression, Post Menopausal
The Effects of Estrogen Withdrawal on Mood Symptoms in Women
This study evaluates the effects on mood when stopping estrogen replacement therapy. The purpose of this study is to investigate the effects of estrogen levels on perimenopausal depression.
- Conditions
- Perimenopausal Depression, Post Menopausal, Healthy, Depression
- Trial name
- NCT00060736
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Bipolar Disorder
Prevention of Mood Disorders by Folic Acid Supplementation
The purpose of this study is to determine whether daily folic acid supplements can prevent new episodes of mood disorder in young people (aged 14-24 years) of biological parents with current or past history of depression or…
- Trial name
- PRE-EMPT (NCT00459264)
- Testing
- Folic Acid
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Major Depression
Comparison of Venlafaxine and Fluoxetine in the Treatment of Postmenopausal Women With Major Depression
Women are more prone to depression at certain points of the life cycle, although the etiologic and therapeutic implications remain largely unknown1,2.
- Trial name
- NCT01824433
- Testing
- venlafaxine, fluoxetine
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Capital Medical University
Treatment Resistant Depression
Deep Brain Stimulation in Treatment Resistant Depression
Recurrent major depressive disorder affects about 3-5% of the population. It is anticipated that by 2020, depression will be the most common cause of disability worldwide in the 18-55 age group.
- Trial name
- NCT01435148
- Testing
- Deep Brain Stimulation, implanted
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- North Bristol NHS Trust
PTSD, Depression
Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children
The goal of this study is to assess Parenting STAIR Modular (PSTAIR-M), a promising and innovative intervention for military-connected mothers (MCM) who have experienced trauma and their young children (ages 2-10).
- Conditions
- PTSD, Depression, Parent-Child Relations
- Trial name
- NCT06262178
- Testing
- Parenting-STAIR Modular (PSTAIR-M)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- New York University
Acne Vulgaris
Acne and Mood: Impact of Treatment on Depression, Anxiety, and Sexual Function
This study seeks to examine if there is any relationship between spironolactone use prescribed for acne vulgaris and depression, anxiety, and/or sexual function.
- Trial name
- NCT03921476
- Testing
- Online survey
- Where
- United States
- Sponsor
- Northwestern University
Arthritis, Diabetes
Can Mental Health Chatbots Help Chronic Disease Populations?
Past research has shown that patients suffering from chronic health conditions tend to experience high levels of negative mental health symptoms (e.g., depression).
- Conditions
- Arthritis, Diabetes, Depression, Anxiety
- Trial name
- NCT04620668
- Testing
- Wysa
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Luke MacNeill
Depression, Postpartum
Determining the Effect of Telephone Counseling Service Provided to Primiparous Mothers on Postpartum Depression
The aim of this study is to determine the effect of telephone counseling services provided to primiparous mothers on postpartum depression.
- Trial name
- NCT06070168
- Testing
- Telephone Counseling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Major Depressive Disorder (MDD)
Home-Based Transcranial Direct Current Stimulation In Major Depressive Disorder (HOME)
Depression is a prevalent and debilitating disorder. The most common treatments are antidepressant medications and talking therapies. However, for many individuals, these are not their treatment of choice.
- Trial name
- HOME (NCT07228468)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- 6 sites in United Kingdom
- Volunteers
- 438 people
- Sponsor
- King's College London
Depression
Inflammatory Biomarkers and Brain Metabolites, a Study Based on Magnetic Resonance Spectroscopy
Suicidal behaviors (SB) are a major health problem in France : 10 000 suicides and 220 000 suicide attempts every year. SB management is therefore a major public health issue.
- Trial name
- BICS (NCT03052855)
- Testing
- Magnetic Resonance Imaging (MRI) and biological samples
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Brain Tumour, Depressive Symptoms
Mindfulness-Based Therapy for Brain Tumour Survivors
Brain Tumour (BT) survivors struggle with disabling physical, emotional, cognitive and psychosocial sequelae. Unfortunately, to-date there has been very limited research into rehabilitative interventions for this population.
- Conditions
- Brain Tumour, Depressive Symptoms, Survivors
- Trial name
- NCT02792608
- Testing
- Mindfulness-based Therapy
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Sunnybrook Health Sciences Centre
Depression, Traumatic Brain Injury
Mindfulness-Based Cognitive Therapy Intervention to Treat Depression in Individuals With a Traumatic Brain Injury
The purpose of this study is to determine whether mindfulness-based cognitive therapy is effective in reducing depression symptoms in individuals who have experienced a traumatic brain injury.
- Trial name
- NCT00745940
- Testing
- MBCT for TBI
- Where
- 3 sites in Canada
- Volunteers
- 105 people
- Sponsor
- Lakehead University
Major Depressive Disorder, Depression
Nitrous Oxide- Suicidal Ideation
Most clinical major depression responds to standard treatments (medication and psychotherapy); however, a significant subset of depressed patients (15-20%) do not respond to these treatments and are referred to as…
- Conditions
- Major Depressive Disorder, Depression, Mood Disorders, Suicidal Ideation
- Trial name
- NCT03736538
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Breast Cancer Female, Chemotherapy Effect
Quality of Life Improvement During Chemotherapy
This study is a randomized controlled trial, taking place at the University Hospital Basel (CH). It aims at the alleviation of breast cancer patients' life quality during chemotherapy.
- Trial name
- QoLMa (NCT04694885)
- Testing
- Structured Hypnotherapy
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- University Hospital, Basel, Switzerland
Depression
Efficacy and Safety of Low Amplitude Electroconvulsive Therapy
The purpose of this study is to demonstrate the clinical feasibility of low amplitude electroconvulsive therapy (ECT) to reduce, and possibly eliminate the side effects of ECT by lowering the strength of the ECT stimulus from the…
- Trial name
- NCT02351843
- Testing
- MECTA Spectrum 5000Q
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Duke University
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