Clinical trials: Depression, Anxiety, Stress
Depression, Anxiety
A Coach-Guided Online Acceptance and Commitment Therapy (ACT) Intervention for Stroke Survivors
The pilot randomized controlled trial aims to assess effects of a guided online acceptance and commitment therapy (ACT) intervention on distressed stroke survivors compared to the care-as-usual control group.
- Conditions
- Depression, Anxiety, Stress, Stroke
- Trial name
- NCT05097040
- Testing
- acceptance and commitment therapy (ACT)
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Pancreatic Tumor, Benign, Pancreatic Cancer, Adult
Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer
This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer.
- Conditions
- Pancreatic Tumor, Benign, Pancreatic Cancer, Adult, Pancreatic Cancer Resectable
- Trial name
- MIND-PANC (NCT07529626)
- Where
- 3 sites in China
- Volunteers
- 320 people
- Sponsor
- Shanghai Zhongshan Hospital
Anxiety, Depression
Project THINK: Trial of a Brief Cognitive Restructuring Intervention
This project will involve testing a brief (~30 minute) digital intervention aimed at teaching youth the evidence-based strategy of changing unhelpful thoughts (i.e., cognitive restructuring).
- Conditions
- Anxiety, Depression, Stress
- Trial name
- NCT05720741
- Testing
- Project THINK, Project SHARE
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Harvard University
Emotional Distress, Anxiety
Mindfulness Intervention for Emotional Distress: An EEG Study
This is a randomized controlled trial examining the efficacy and neural mechanisms of a standardized Mindfulness Intervention for Emotional Distress (MIED) in adults with subclinical emotional distress.
- Conditions
- Emotional Distress, Anxiety, Depression, Stress (Psychology)
- Trial name
- MIED-RCT (NCT07692269)
- Testing
- MIED, PMR
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University
Episodic Migraine, Chronic Migraine
CGRP Inhibition, Autonomic Function, and Migraine
The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e.
- Trial name
- CGRP-1 (NCT04628429)
- Testing
- Erenumab, Galcanezumab, Fremanezumab
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Psychological Distress, Depression
Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Many survivors of the intensive care unit (ICU) suffer from persistent symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD).
- Conditions
- Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- NCT02701361
- Testing
- mobile mindfulness, standard mindfulness, education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Duke University
Stroke, Stress
Impact of Mindfulness on Psychological Well-being of Stroke Survivors and Their Caregivers
This study will employ a randomized control design. Stroke survivors and family caregivers will be recruited for the study, and randomized either to receive mindfulness-based intervention or health education.
- Conditions
- Stroke, Stress, Anxiety, Depression
- Trial name
- SOMII (NCT03910855)
- Testing
- Mindfulness Based Intervention, Health Education Program
- Where
- Singapore
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Alcohol Drinking Related Problems, Alcohol Use Disorders
Co-occurence of Mental Illness and Problematic Alcohol Use: an Internet-based Cognitive Behavior Therapy Intervention
The goal of this clinical trial is to learn if internet-based cognitive behavior therapy (ICBT ) works to treat co-occurent of problematic alcohol use and mental illness including mild to moderate symptoms of either depression…
- Conditions
- Alcohol Drinking Related Problems, Alcohol Use Disorders, Depressive Disorders, Mental Illness
- Trial name
- CoMiT (NCT06789250)
- Testing
- Internet-based cognitive behavior therapy
- Where
- 2 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Linkoeping University
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS: Stress Reduction for Refugees
The COVID-19 pandemic crisis is associated with a wide range of stressors for the general population. For forcibly displaced persons (FDPs), the turmoil of this crisis is magnified significantly, and elevated pre-existing…
- Trial name
- NCT04761510
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Haifa
COVID-19 Post-Intensive Care Syndrome
Impact of Mental Health and Cognitive Disorders on Quality of Life in Severe Covid-19 Survivors
The objective of this single-center retrospective observational study is to describe cognitive and psychological outcomes and their impact on quality of life after at least 3 months of intensive care unit (ICU) discharge in…
- Trial name
- NCT05839327
- Testing
- Montreal cognitive assessment scale (MOCA)
- Volunteers
- 65 people
- Sponsor
- Hospital Sao Domingos
Stress, Anxiety
The Effects of Smell on Mood and Physical Responses
The purpose of this study is to examine the body's response to relaxing and stimulating fragrances commonly used in aromatherapy.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT00097253
- Testing
- Exposure to relaxant and stimulant odors
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Depression, Anxiety
Using Virtual Reality Technology on Depression, Anxiety, and Stress Among Palestinian Patients Undergoing Breast Biopsy
The goal of this randomized controlled trial was to investigate the impact of Virtual Reality (VR) technology on depression, anxiety, and stress levels among Palestinian patients undergoing breast biopsy.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- VR/RCT (NCT07267741)
- Testing
- Meta Quest 2 VR headset
- Volunteers
- 80 people
- Sponsor
- Nablus University for Vocational and Technical Education
Psychological, Burnout
Psychological Support for Intensive Care Nurses During the COVID-19 Pandemic: The PROACTIVE Feasibility Trial
The psychological health of frontline healthcare workers, caring for critically ill patients with COVID-19, has deteriorated during the pandemic. Nurses appear to be most seriously affected.
- Conditions
- Psychological, Burnout, Post Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05087186
- Testing
- Guided imagery and FLASH technique
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Healthy, Psychological Distress
The Effects of the Somatic Intervention 'Dance-Walk' on Body Awareness, Vitality, and Mental Health in Help-Seeking Adults: a RCT Study
The goal of this clinical trial is to learn if a movement program called "Dance-Walk" can improve body awareness, energy levels, and mental health in adults seeking mental health support.
- Conditions
- Healthy, Psychological Distress, Stress, Depression Disorders
- Trial name
- DANCEWALK (NCT07024901)
- Testing
- Dance-walk
- Where
- Lithuania
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Pregnant Women
The Effect of Self-Compassion Based Birth Preparation Program
The pregnancy period, during which physiological, psychological and social changes occur, can negatively affect women mentally. It is stated that women's concerns about their own and their baby's health, anxiety and fear…
- Trial name
- NCT07187557
- Testing
- A self-compassion based birth preparation program
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Mediation, Mood
Inner Engineering Yoga Program on Short and Long Term Health Effects (ISHA-Impact): A Longitudinal Study
This study will include any participant who registered, and plans to attend the Inner Engineering In-Person Completion Course. In 2019, this course was offered in: Los Angeles in March, Philadelphia in April and Toronto \& Dallas…
- Conditions
- Mediation, Mood, Stress, Habits
- Trial name
- ISHA-Impact (NCT04189146)
- Testing
- Inner Engineering Intervention
- Where
- United States
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Depression, Anxiety, Disruptive Behavior Disorder
Improving Social, Emotional, Behavioral, and Academic Functioning
This efficacy trial will evaluate the impact of an enhanced version of the Interconnected Systems Framework (ISFE) on elementary school-based team functioning, including use of evidence-based practices, and student emotional…
- Conditions
- Depression, Anxiety, Disruptive Behavior Disorder, Trauma, Psychological
- Trial name
- NCT05425381
- Testing
- Enhanced version of Interconnected Systems Framework, Positive Behavioral Interventions and Supports with Co-located School Mental Health
- Where
- 2 sites in United States
- Volunteers
- 1,208 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Caregivers
Improving Outcomes for Care Partners of Persons With Traumatic Brain Injury
Care partners of persons with traumatic brain injury (TBI) are often faced with considerable physical and emotional stress resulting from their caregiver role.
- Trial name
- NCT04570930
- Testing
- Just-in-time adaptive intervention (JITAI), Control
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stress, Anxiety
Tools for Wellbeing COVID-19 National Study of Undergraduate Students
The study evaluates the effectiveness of yoga practices on reducing stress, negative emotion, anxiety, and depression and on increasing positive emotion, wellbeing and resilience. The study uses randomized wait-list control.
- Conditions
- Stress, Anxiety, Depression, Resilience
- Trial name
- NCT04414371
- Testing
- Yoga
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Stress Disorders, Post-Traumatic, Depressive Symptoms
Treatment for Veterans With Military Sexual Trauma
The purpose of this study is to evaluate the effectiveness of Cognitive Processing Therapy (CPT) versus Present-Centered Therapy (PCT) in treating current post-traumatic stress symptoms associated with sexual assault that…
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Symptoms, Anxiety Symptoms, Quality of Life
- Trial name
- NCT00371644
- Testing
- Cognitive Processing Therapy, Present-Centered Therapy
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- US Department of Veterans Affairs
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