Clinical trials: Depression, Postpartum
Postpartum Depression, Sleep Disorder
The Effects of Pregnancy Classes and Contributing Factors to Postpartum Depression
It is recommended by the American College of Obstetricians and Gynecologists' Committee on Obstetric Practice that all obstetricians screen each women for postpartum depression and anxiety with a validated instrument.
- Conditions
- Postpartum Depression, Sleep Disorder, Breast Feeding, Self Esteem
- Trial name
- NCT03763435
- Testing
- Antenatal pregnancy classes
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Bartin State Hospital
Postpartum Depression (PPD), Pregnancy
Clinical Validation of a Predictive Test for Postpartum Depression
The goal of this observational study is to develop a blood test that may be predictive of postpartum depression. This Blood test is investigational and not yet FDA approved.
- Trial name
- PREVAIL (NCT06831968)
- Testing
- Enlighten
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Postpartum Depression, Heart Rate Variability
Vitamin B6 and Depression in Pregnant and Peri-partum Women
Perinatal depression is a highly prevalent and serious health issue during pregnancy. According to statistics, approximately one out of every ten postpartum women experiences this condition.
- Trial name
- NCT06445933
- Testing
- Vitamin B6
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postpartum Depression
A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression
The primary purpose of this study was to determine if treatment with SAGE-217 reduces depressive symptoms in participants with severe postpartum depression (PPD) compared to placebo as assessed by the change from baseline in the…
- Trial name
- NCT02978326
- Testing
- SAGE-217 15/20 mg Oral Solution, SAGE 217 30 mg Capsules
- Where
- 27 sites in United States
- Volunteers
- 276 people
- Sponsor
- Biogen
Post-partum Depression
Pilot Study on the Use of Acupuncture for Postpartum Depression
The proposed study is a randomized controlled trial to examine the efficacy and safety of active acupuncture versus placebo acupuncture for the treatment of postpartum depression.
- Trial name
- NCT01178008
- Testing
- Active acupuncture
- Where
- 3 sites in Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Postpartum Depression
Prevention of Postpartum Depression: A Pilot Placebo-controlled Trial of Trazodone
Postpartum depression is a serious illness that affects approximately 17% of women who have recently given birth. Untreated depression appears to have negative effects for both the mother and her baby.
- Trial name
- NCT05299398
- Testing
- Trazodone
- Where
- Canada
- Sponsor
- Verinder Sharma
Depression During Pregnancy, Depression, Postpartum
IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression
The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations.
- Trial name
- NCT06746337
- Testing
- IMAGINE
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postpartum Depression, Melatonin
Postpartum Depression
Our aim was to diagnose and initiate early treatment for postpartum depression by detecting the changes of melatonin levels in c-sections with different antesthesia modalities.
- Trial name
- NCT04278456
- Testing
- postpartum depression
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Erzincan University
Postpartum Depression, Breast Feeding
Carrying for the Culture
Suboptimal postpartum health outcomes in the US, including low rates of lactation and high rates of postpartum depression, contribute to high rates of perinatal mortality and morbidity as well as long-term and intergenerational…
- Trial name
- NCT06148831
- Testing
- Infant Carrier
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nurturely
Postpartum Depression (PPD)
PREPP: Preventing Postpartum Depression
The primary aim of this study is to determine if a behavioral intervention targeting maternal caregiving of young infants can increase infant sleep and reduce fuss/cry behavior, and thereby (1) reduce the incidence and/or…
- Trial name
- PREPP (NCT03283254)
- Testing
- Practical Resources for Effective Postpartum Parenting (PREPP), Enhanced Treatment As Usual (ETAU)
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Columbia University
Postpartum Depression
Effects of Esketamine on Postpartum Depression
Different concentrations of Esketamine were used after cesarean section. Through the evaluation of postoperative psychological status and analgesic effect, the optimal dosage of Esketamine to exert the effects of depression and…
- Trial name
- EEPD (NCT05229913)
- Testing
- Esketamine is not added, Esketamine 0.2mg/kg, Esketamine 0.4mg/kg
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Qinghai University
Postpartum Depression
Does Enhancing Maternal Peer Interactions Decrease Rates of Postpartum Depression?
The long-term goal of this study is to validate a simple and inexpensive intervention to reduce the incidence and impact of Postpartum Depression (PPD).
- Trial name
- NCT03793569
- Testing
- Peer discussion group
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Postpartum Depression, Postnatal Depression
Phase 2 Clinical Trial of GH001 in Postpartum Depression
This study is a multicenter, open-label, single-arm Phase 2 clinical trial. Approximately 15 female participants with clinically diagnosed postpartum depression (PPD) will be included in this study.
- Trial name
- NCT05804708
- Testing
- GH001
- Where
- 4 sites in Netherlands, United Kingdom
- Volunteers
- 10 people
- Sponsor
- GH Research Ireland Limited
Depression, Depression, Postpartum
Effectiveness of Supplemental Calcium in Preventing Postpartum Depression
This study will evaluate the effectiveness of taking supplemental calcium while pregnant in reducing the risk of postpartum depression.
- Trial name
- NCT00228033
- Testing
- Elemental calcium (as carbonate)
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pregnancy, Postpartum Period
Effect of Exercise on Perinatal Depression
Fifteen percent of women experience depression during pregnancy or postpartum (i.e., perinatal depression). Furthermore, 38% of low income women experience postpartum depression.
- Conditions
- Pregnancy, Postpartum Period, Depression
- Trial name
- NCT02791932
- Testing
- Exercise
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression
Effectiveness of Group Interpersonal Psychotherapy in Treating Women With Prenatal Depression
This study will evaluate the effectiveness of group interpersonal psychotherapy for preventing postpartum depression in pregnant women with depression and for improving healthy outcomes in their babies.
- Trial name
- NCT00633178
- Testing
- Group interpersonal therapy (IPT), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Depressive Symptoms, Urinary Incontinence
BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Urinary Incontinence in Postpartum and Early Post-Childbirth Women
The goal of this clinical trial is to evaluate if the combined treatment with EXOMIND (BTL-699-2) and EMSELLA (HPM-6000UF) devices is able to improve depressive symptoms and urinary incontinence in women who delivered a healthy…
- Trial name
- NCT07413692
- Testing
- EXOMIND (BTL-699-2) ActiveTreatment, EMSELLA (HPM-6000UF) ActiveTreatment
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- BTL Industries Ltd.
Postnatal Depression, Self Efficacy
Effectiveness of 'Supportive Parenting App' on Parental and Newborn Outcomes
The Supportive Parenting App is a theory-based perinatal educational intervention for couples administered through a mobile application.
- Conditions
- Postnatal Depression, Self Efficacy, Parent-Child Relations, Development, Child
- Trial name
- NCT04706442
- Testing
- Supportive Parenting Application
- Where
- Singapore
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Breast Feeding, Exclusive, Post Partum Depression
The Impact of a Daily Smartphone-based Communication Among Postpartum Women on Breastfeeding Rates
We will aim to study the impact of introducing a smartphone-based daily feedback and communication platform between postpartum women delivering at our institute and a multidisciplinary breastfeeding-support team (obstetricians…
- Trial name
- NCT04135612
- Testing
- Smartphone based communication
- Where
- Israel
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Maternal Health Services, Infant, Newborn
Comparing Integrative Midwife-led vs. Fragmented Inpatient Postpartum Care: Impact on Satisfaction and Transition to Motherhood
The goal of this clinical trial is to compare two different forms of postnatal care to find out which is most beneficial for mothers and their children after birth and with which they are most satisfied.
- Conditions
- Maternal Health Services, Infant, Newborn, Postnatal Care, Breast Feeding
- Trial name
- SMILE (NCT07077941)
- Testing
- Integrative care
- Where
- Austria
- Volunteers
- 784 people
- Sponsor
- Medical University of Vienna