Clinical trials: Depression/Anxiety
Cancer
Psilocybin Cancer Anxiety Study
The primary objective of this double-blind, placebo-controlled pilot study is to assess the efficacy of psilocybin administration (4-phosphoryloxy-N,N-dimethyltryptamine), a serotonergic psychoactive agent, on psychosocial…
- Trial name
- NCT00957359
- Testing
- Psilocybin, Niacin
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- NYU Langone Health
Anxiety, Depression
Improving Adherence to Homework During Therapy
The purpose of this study is to expand Adhere.ly- a simple, HIPAA-compliant, web-based platform to help therapists engage clients in practicing therapeutic skills between sessions (homework) during mental health treatment by…
- Conditions
- Anxiety, Depression, Depression/Anxiety
- Trial name
- Adherely STTR (NCT05866185)
- Testing
- Therapy, Therapy + Adhere.ly
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of South Florida
Parkinson's Disease, Depression
Barriers to Mental Healthcare Utilization in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder in the elderly. In most people, the illness is complicated by co-occurring psychiatric problems such as depression and anxiety.
- Conditions
- Parkinson's Disease, Depression, Anxiety
- Trial name
- NCT01167608
- Testing
- No Intervention. This is a cross-sectional survey study.
- Where
- United States
- Volunteers
- 883 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Insomnia, Depression
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
There is a strong association between sleep disturbance and suicidal thoughts and behaviors. Sleep disturbance is also highly comorbid with other common conditions associated with suicide such as depression and posttraumatic…
- Conditions
- Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
- Trial name
- NCT02248675
- Testing
- CBT-I, TAU
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Psychological Distress, Anxiety
Acceptance and Commitment Therapy for Older Adults
Title: Acceptance and Commitment Therapy for older adults experiencing psychological distress: A hermeneutic single case efficacy design (HSCED) series.
- Conditions
- Psychological Distress, Anxiety, Depression
- Trial name
- NCT04280445
- Testing
- Psychological therapy
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Lincoln
Panic Disorder, Depression
Drug Use Investigation of Jzoloft.
The objective of this surveillance is to collect information about 1) adverse drug reactions not expected from the LPD (unknown adverse drug reactions), 2) the incidence of adverse drug reactions in this surveillance, and 3)…
- Trial name
- NCT00605865
- Testing
- Sertraline hydrochloride
- Volunteers
- 2,272 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Depression, Anxiety
Community Study of Outcome Monitoring for Emotional Disorders in Teens
This study is being done to compare three types of talk therapies for youth who struggle with emotional and behavioral problems (e.g., anxiety, sadness, worries) in Community Mental Health Clinics in Connecticut (CT) and Florida…
- Trial name
- COMET (NCT02567266)
- Testing
- Unified Protocol for Adolescents (UP-A), Youth Outcomes Questionnaire, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 196 people
- Sponsor
- University of Miami
Covid19, Mental Health
Mental Health Among Patients, Providers, and Staff During the COVID-19 Era
The Mental Health Among Patients, Providers, and Staff (MHAPPS) Study is designed to study how the COVID-19 pandemic has affected mental health and wellbeing, and how to support mental health while minimizing the burden on the…
- Trial name
- MHAPPS (NCT04700137)
- Testing
- Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Cardiovascular Diseases
Comparison of Traditional, Web-based or a Combined Cardiac Rehabilitation Programme
The study explores the different modes of Cardiac Rehabilitation delivery including the use of a web-based programme. Cardiac Rehabilitation provides a structured, comprehensive programme, proven to reduce cardiovascular…
- Trial name
- NCT05326529
- Testing
- Hospital Based Cardiac Rehabilitation Exercise Classes, Web-based Cardiac Rehabilitation Exercise Sessions
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- University of Chester
Post-Traumatic Stress Disorder, Depression
Evaluation of Two Community-based Mental Health Interventions for Violence-Displaced Afro-Descendants in Colombia.
This study is a community prevention randomized trial with three parallel groups: two intervention groups and one control group in Buenaventura and Quibdó.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Anxiety, Violence
- Trial name
- ACOPLE (NCT01856673)
- Testing
- Common Elements Treatment Approach, Narrative Community Group Therapy, Standby group
- Where
- 2 sites in Colombia
- Volunteers
- 521 people
- Sponsor
- Universidad del Valle, Colombia
Pain, Function
Preventing Persistent Post-Surgical Pain and Dysfunction
Primary Aim: To examine the superior efficacy of ACT versus Attention Control (AC) on postoperative pain intensity and functioning in at-risk Veterans undergoing TKA.
- Conditions
- Pain, Function, Anxiety, Depression
- Trial name
- PrePARE (NCT03965897)
- Testing
- Acceptance and Commitment Therapy (ACT), Attention Control (AC)
- Where
- United States
- Volunteers
- 402 people
- Sponsor
- University of Iowa
Psychological Distress, Depression
Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Many survivors of the intensive care unit (ICU) suffer from persistent symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD).
- Conditions
- Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- NCT02701361
- Testing
- mobile mindfulness, standard mindfulness, education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Duke University
Stress, Anxiety
The Effects of Smell on Mood and Physical Responses
The purpose of this study is to examine the body's response to relaxing and stimulating fragrances commonly used in aromatherapy.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT00097253
- Testing
- Exposure to relaxant and stimulant odors
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Caregivers
Improving Outcomes for Care Partners of Persons With Traumatic Brain Injury
Care partners of persons with traumatic brain injury (TBI) are often faced with considerable physical and emotional stress resulting from their caregiver role.
- Trial name
- NCT04570930
- Testing
- Just-in-time adaptive intervention (JITAI), Control
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stress Disorders, Post-Traumatic, Depressive Symptoms
Treatment for Veterans With Military Sexual Trauma
The purpose of this study is to evaluate the effectiveness of Cognitive Processing Therapy (CPT) versus Present-Centered Therapy (PCT) in treating current post-traumatic stress symptoms associated with sexual assault that…
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Symptoms, Anxiety Symptoms, Quality of Life
- Trial name
- NCT00371644
- Testing
- Cognitive Processing Therapy, Present-Centered Therapy
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- US Department of Veterans Affairs
Onychophagia
Use of N-Acetylcysteine (NAC) in Fingernail Biting
To conduct a pilot randomized placebo-controlled feasibility trial of N-acetylcysteine (NAC) in onychophagia, preliminarily assessing the tolerability and effects of this pharmacotherapy on young adults who bite their…
- Trial name
- NCT01993849
- Testing
- N-Acetylcysteine (NAC)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Kevin Gray, MD
Treatment Resistant Depression, Generalized Anxiety Disorder
An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay
Genomind has developed and introduced a battery of genetic tests, the Genecept Assay, which clinicians can administer to patients using a simple saliva sample technique. The present study proposes to enroll 1.
- Trial name
- COM-1 (NCT01507155)
- Testing
- Genecept Assay
- Where
- United States
- Volunteers
- 685 people
- Sponsor
- Genomind, LLC
Depression, Postpartum, Anxiety
Preventing Postpartum Depression With Intranasal Oxytocin
The purpose of this study is to test a new treatment for preventing childbirth-related mental illness in postpartum mothers. The treatment is aimed at enhancing maternal bonding, reducing postpartum depression (PPD) and anxiety…
- Trial name
- IN-OXT (NCT02505984)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Chronic Low-back Pain, Anxiety
EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain
The aim of this randomized controlled trial (RCT) is to assess outcomes for virtual reality therapy (including pain intensity, pain interference, anxiety, depression, physical function, sleep, behavioral skills development…
- Conditions
- Chronic Low-back Pain, Anxiety, Depression
- Trial name
- AVR_HEOR (NCT05263037)
- Testing
- EaseVRx
- Where
- United States
- Volunteers
- 1,093 people
- Sponsor
- AppliedVR Inc.