Clinical trials: Depression, suspended
Mild to Moderate Depressive Symptoms
Effectiveness of Online Group-based Nonviolent Communication Interventions
This is a randomized controlled trial (RCT) to test the effectiveness of nonviolent communication (NVC) intervention for reducing parenting stress to parents with children in primary schools and mild to moderate depression.
- Trial name
- NCT05371002
- Testing
- Online group nonviolent communication (NVC) interventions, Waitlist control group
- Where
- China
- Volunteers
- 250 people
- Sponsor
- The University of Hong Kong
Major Depressive Disorder
Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression
Patients with major depressive disorder (MDD) exhibit increased levels of rumination (i.e. repetitive thinking and focus on negative mood states) which have been found to increase the risk of depressive relapse.
- Trial name
- NCT05933148
- Testing
- Siemens 7T MRI
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression
Testing the Effectiveness of Cognitive Training Among Depressed Patients Receiving Esketamine Treatment
In a sample of patients already receiving esketamine treatment as part of their clinical care, this project seeks to test whether we can improve depression by introducing helpful information delivered by a computer-based training…
- Trial name
- NCT05719909
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Refractory Depression, Anxiety Disorders
Focused Ultrasound and Exosomes to Treat Depression, Anxiety, and Dementias
This study is designed to evaluate the safety and efficacy of exosome deployment with concurrent transcranial ultrasound in patients with refractory, treatment resistant depression, anxiety, and neurodegenerative dementia.
- Conditions
- Refractory Depression, Anxiety Disorders, Neurodegenerative Diseases
- Trial name
- NCT04202770
- Testing
- Exosomes
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Neurological Associates of West Los Angeles
Depression, Anxiety
HRV Biofeedback for Brain Tumour Survivors
This study is designed to take a first step toward testing the efficacy and acceptability of heart rate variability biofeedback (HRVB) as a means of ameliorating psychological distress in survivors of Primary Brain Tumour (PBT).
- Conditions
- Depression, Anxiety, Sleep Impairment
- Trial name
- NCT01772498
- Testing
- heart rate variability biofeedback
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- British Columbia Cancer Agency
Treatment-Resistant Depression
pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Depression
We aim to evaluate the safety and efficacy of pBFS-guided high-dose rTMS therapy with short inter-session interval for patients with treatment-resistant depression
- Trial name
- NCT05842291
- Testing
- Active rTMS with short inter-session interval, Active rTMS with long inter-session interval
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changping Laboratory
Major Depressive Disorder
Intermittent Theta Burst Stimulation for MDD
This study will evaluate the effectiveness of intermittent Theta Burst Stimulation for patients with Major Depressive Disorder.
- Trial name
- iTBS (NCT02506127)
- Testing
- Neuronetics XPLOR system
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Depression, Unipolar, Depression, Bipolar
IM Ketamine vs Midazolam for Suicidal ER Patients
Rising US suicide rates and the increased risk of suicide among persons who visit an emergency department (ED) for suicidality make the ED an important site for interventions to prevent suicide.
- Conditions
- Depression, Unipolar, Depression, Bipolar, Suicidal Ideation
- Trial name
- NCT04640636
- Testing
- Ketamine hydrochloride injection, Midazolam injection
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- New York State Psychiatric Institute
Anxiety Depression, Aneurysm Cerebral
Psychiatric Outcomes of Unruptured Intracranial Aneurysms (POUIA)
The impact of cerebrovascular procedures on patients experiencing anxiety and depression is not well studied despite the high prevalence of these mental health disorders.
- Conditions
- Anxiety Depression, Aneurysm Cerebral, Mental Health Wellness 1
- Trial name
- POUIA (NCT06123325)
- Testing
- Clipping, Endovascular embolization, Surveillance imaging
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Montefiore Medical Center
Depressive Disorder
Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression
This is a prospective, multicenter, randomized, double-blind, controlled study to evaluate the effectiveness of PEER Interactive to inform treatment in subjects with a primary diagnosis of depression with comorbidity of…
- Trial name
- NCT01794559
- Testing
- PEER Interactive Report
- Where
- 2 sites in United States
- Volunteers
- 1,922 people
- Sponsor
- MYnd Analytics
Treatment Resistant Depression
Enhanced Spatial Targeting in ECT Utilizing FEAST
The purpose of this research study is to find an alternative version of ECT that reduces the negative side effects (mainly memory loss) while still providing patients with relief from depressive symptoms.
- Trial name
- NCT04099342
- Testing
- FEAST, FEAST RP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Anxiety, Anxiety Disorders
A Single-session Growth Mindset Intervention for Children and Young People With Mental Health Difficulties
The present study aims to evaluate whether an online, self-administered, single session intervention (SSI) increases children and adolescents' perceptions of control over external threats and their emotional experience and…
- Conditions
- Anxiety, Anxiety Disorders, Depression, Low Mood
- Trial name
- NCT04652362
- Testing
- Growth Mindset Online Single-Session Intervention, Supportive Therapy Online Single-Session Intervention (Control)
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Major Depressive Disorder
Evaluation of Response to a Course of Repetitive Transcranial Magnetic Stimulation Using Vocal Biomarkers
Voice recordings taken prior to the start of repetitive transcranial magnetic stimulation (rTMS) therapy will be used to develop a predictive model of treatment response using machine learning for patients with major depressive…
- Trial name
- SPEECHTMS (NCT06451835)
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- 9 sites in France
- Volunteers
- 156 people
- Sponsor
- GCS CIPS
Bi-Polar Disorder, Autism Spectrum Disorder (ASD)
An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms
The purpose of this study is to evaluate QbMobile's ability to collect objective data to identify specific symptom profiles in differential diagnoses (ASD, MDD, Bipolar Disorder and Anxiety Disorder) that are common with ADHD.
- Conditions
- Bi-Polar Disorder, Autism Spectrum Disorder (ASD), Major Depression Disorders, Separation Anxiety Disorder
- Trial name
- NCT07329673
- Testing
- Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Qbtech AB
Depression, Tuberculosis
Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South Africa
This hybrid type I effectiveness-implementation trial will increase understanding of the effectiveness and cost-effectiveness of integrating a brief evidence-based treatment for major depressive disorder (MDD) within the…
- Trial name
- NCT05091580
- Testing
- Interpersonal Counseling, Enhanced treatment as usual
- Where
- South Africa
- Volunteers
- 500 people
- Sponsor
- New York State Psychiatric Institute
Mental Health Wellness 1
The Effects of Trauma-sensitive Yoga and Tai Chi on Mental Health
A three-arm randomized control trial design was used to test the effectiveness of (1) Chen Style Tai Chi (TC) and talk therapy; (2) Trauma-Sensitive Yoga and talk therapy in comparison to (3) talk therapy only (control group) on…
- Trial name
- TSY/TC (NCT04754009)
- Testing
- Trauma-Sensitive Yoga + TAU, Chen Style Tai Chi + TAU, Treatment as Usual
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Depression
The Taste-Mood Diagnostic Study
The study looks at whether a taste test device can be used as a diagnostic aid for depression. Taste tests will be carried out before and after first use of an antidepressant (prescribed by the patient's GP) and then again six to…
- Trial name
- NCT03645447
- Testing
- Taste test
- Where
- 4 sites in United Kingdom
- Volunteers
- 240 people
- Sponsor
- Ranvier Health Ltd
Major Depressive Disorder
Prediction of the Response to a Course of Transcranial Magnetic Stimulation (rTMS) Based on Heart Rate Variability
Changes in heart rate variability following a single session of rTMS will be tested as a predictor of response to a course of 30 rTMS sessions in patients with major depressive disorder (MDD).
- Trial name
- DEP&MOD (NCT06451809)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- 9 sites in France
- Volunteers
- 160 people
- Sponsor
- GCS CIPS
Neurocognitive Disorders, Dementia
Major Memory 2: A Long-term Group Cognitive Stimulation Program
This study aims to evaluate the effect of a long-term group cognitive stimulation (CS) program on the cognitive function of institutionalized elderly people with neurocognitive disorders.
- Conditions
- Neurocognitive Disorders, Dementia, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT04178564
- Testing
- Cognitive Stimulation
- Where
- 8 sites in Portugal
- Volunteers
- 70 people
- Sponsor
- Rsocialform - Geriatria, Lda
Depressed GCS
CaffeinICU Study - A Study on Oral Caffeine in ICU Patients With Coma
Background: Depressed Glasgow Coma Scale (GCS) is common among critically ill patient s in the intensive care unit (ICU). It is one of the main reasons that hampers liberation from mechanical ventilation among ICU patients.
- Trial name
- CaffeinICU (NCT05232734)
- Testing
- Caffeine Citrate 20 MG/ML Oral Solution
- Where
- Singapore
- Volunteers
- 10 people
- Sponsor
- Singapore General Hospital