Clinical trials: Depression Chronic
Depression
Supported Online Self-Help for Veterans With Depression in Primary Care
Depression is disabling and affects one in five Veterans. VA's Primary Care-Mental health Integration (PCMHI) enables specialists to support medication treatment in primary care, but timely and sufficient access to psychotherapy…
- Trial name
- SOS-Depression (NCT07781228)
- Testing
- Enhanced Usual Care (EUC), Supported Online Self-help for Depression (SOS-Depression)
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of California, Los Angeles
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Deprescribing, Antidepressant
General Practitioner & Pharmacist Support for Discontinuing Long-term Antidepressants in Clinically Stable Patients
In Belgium, many adults who have suffered from depression keep using antidepressants on a daily basis for years afterwards, sometimes longer than guidelines recommend.
- Conditions
- Deprescribing, Antidepressant, Depression Disorder, Discontinuation
- Trial name
- GPS-AD (NCT07398053)
- Testing
- GPS-AD intervention
- Volunteers
- 324 people
- Sponsor
- University Ghent
Depressive Disorders, Anxiety Disorders
A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD
The literature and our preliminary studies found that in COPD patients, psychosocial factors affect quality of life (QOL) and functioning more than would be expected given the severity of their disease.
- Conditions
- Depressive Disorders, Anxiety Disorders, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT00105911
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- US Department of Veterans Affairs
Chronic Tinnitus, Anxiety
Internet-Based Mindfulness-Based Cognitive Therapy (iMBCT) for Chronic Tinnitus Patients
This study tested a 6-week, internet-based Mindfulness-Based Cognitive Therapy (MBCT) program designed to help people experiencing distress related to chronic tinnitus.
- Conditions
- Chronic Tinnitus, Anxiety, Depressive
- Trial name
- NCT07183826
- Testing
- Mindfulness-Based Cognitive Therapy (Internet-delivered), No intervention
- Where
- Poland
- Volunteers
- 78 people
- Sponsor
- University of Warsaw
Mindfulness, Anxiety
Mindfulness-based Interventions on Stress, Anxiety, and Depression Symptoms in Diabetic Patients
The study was conducted at a private hospital in Istanbul, Turkey, as a randomized controlled experimental trial with a pretest-posttest approach. The study included 70 patients in each group, for a total of 140 patients.
- Conditions
- Mindfulness, Anxiety, Stress, Depression Chronic
- Trial name
- NCT07272304
- Testing
- Mindfullness exercises, Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Emine Ergin
Anxiety, Depression
Anxiety and Depression Perceived by Individuals With and Without Cancer During the COVID-19 Pandemic Period
The COVID-19 pandemic has negatively affected individuals not only physiologically but also psychologically. The aim of this study is to examine the anxiety and depression status of cancer patients, individuals with non-cancer…
- Conditions
- Anxiety, Depression, Covid19, Cancer
- Trial name
- NCT04698044
- Testing
- Hospital Anxiety Depression Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 1,107 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Long COVID
tDCS in the Management of Post-COVID Disorders
Different physical and mental morbidities such as pain, fatigue, depressed mood and cognitive impairment can be triggered by coronavirus infection.
- Trial name
- tDCS (NCT06074848)
- Testing
- Transcranial Direct Current Stimulation (tDCS), Motor Training, Cognitive Training
- Where
- 2 sites in Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco
Insomnia, Depressive Disorder, Major
Cannabinoids as a Treatment for Insomnia in Major Depression
This single-site study is a pilot, three-armed, double-blinded, placebo-controlled randomized controlled trial (RCT) that will determine the feasibility of a definitive RCT investigating the use of cannabis oil as a treatment for…
- Conditions
- Insomnia, Depressive Disorder, Major, Sleep Disorder, Depression
- Trial name
- CANMDD (NCT05041647)
- Testing
- 25:1 CBD/THC, 5:1 CBD/THC
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Chronic Low Back Pain (CLBP)
Chronic Low Back Pain: TOTALSPINE - UO04
Background: Low back pain (LBP) is the primary factor contributing to years lived with disability. In view of the close correlation between the functions of the body, which cannot be examined piecemeal but as an integrated…
- Trial name
- TOTALSPINE (NCT06895317)
- Testing
- Remote rehabilitation, Rehabilitation face to face
- Where
- 2 sites in Italy
- Volunteers
- 86 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Chronic Obstructive Pulmonary Disease
Mindfulness to Mitigate the Effect of Anxiety-depression-fear in Chronic Obstructive Pulmonary Disease (COPD)
People with COPD have a greater risk for symptoms of depression, anxiety, and fear of breathlessness. Those emotions are independently associated with lower physical activity, poorer quality of life, and higher hospitalization…
- Trial name
- NCT03385317
- Testing
- Mindfulness
- Where
- United States
- Sponsor
- Mayo Clinic
Major Depressive Disorder
Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression
The purpose of this study is to examine the effectiveness of brief multifamily psychoeducation to relieve the psychological distress of families of patients with chronic major depression and to improve their family functioning.
- Trial name
- NCT01734291
- Testing
- Family psychoeducation
- Where
- Japan
- Volunteers
- 49 people
- Sponsor
- Nagoya City University
Wound
Prevalence and Variables Associated With Depression in Subjects With Chronic Wounds Using PHQ-9 as a Screening Tool
The objective of the study is to complete a retrospective chart review of subjects who were treated at the Wound Care Clinic at Methodist Dallas Medical Center, presented for treatment between June 2018 and February 2019, and…
- Trial name
- NCT04701632
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Methodist Health System
Chronic Obstructive Pulmonary Disease, Depression
Effectiveness and Cost-effectiveness of Digital Psychological Intervention (EmoEase) in Chinese COPD Patients
Background Mental health issues are common and often overlooked in COPD patients. Digital psychological interventions might help, but their effectiveness in Chinese COPD patients hasn't been studied.
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Anxiety
- Trial name
- NCT06026709
- Testing
- EmoEase
- Volunteers
- 1,200 people
- Sponsor
- Peking Union Medical College
Traumatic Brain Injury, Chronic Pain
One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change
Mild traumatic brain injury (mTBI) is the signature wound of Veterans returning from the operations in Iraq and Afghanistan (i.e., OIF/OEF/OND), with up to 20 percent experiencing persistent post-concussive symptoms.
- Conditions
- Traumatic Brain Injury, Chronic Pain, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT04143243
- Testing
- ACT on Life, Education, Resources, and Support
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Chronic Posttraumatic Stress Disorder (PTSD)
Posttraumatic stress disorder occurs in patients who have experienced, witnessed or have been confronted with an event involving actual death or the threat of death, serious injury, or the threat to physical health and felt fear…
- Trial name
- NCT00001657
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Mental Health (NIMH)
Idiopathic Pulmonary Fibrosis, Chronic Obstructive Pulmonary Disease
Coping Strategies Within Pulmonary Rehabilitation in Patients With IPF and COPD
The aim of this prospective observational trial is to evaluate the influence of Coping strategies on pulmonary rehabilitation outcomes like 6-minute walk distance and Quality of life.
- Trial name
- NCT04257630
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Depression, Anxiety
Depressive and Anxiety Disorders in Patients With Chronic Liver Diseases
The aim of this observational study is to learn about the prevalence of depressive and anxiety disorders among patients with chronic liver diseases
- Trial name
- NCT06113029
- Testing
- The Hamilton Rating Scale for Anxiety, The Beck Depression inventory, Rand SF-36 Questionnaire
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome