Clinical trials: Depression Chronic
Mood Disorders, Depressive Disorders
Clinical Trials of Two Non-drug Treatments for Chronic Depression
This study investigates the potential efficacy of two nonpharmacologic treatments for nonseasonal depression, bright light exposure or high-density negative air ion exposure.
- Conditions
- Mood Disorders, Depressive Disorders, Depression, Chronic Depression
- Trial name
- NCT00006172
- Testing
- Bright light box, High-output negative ion generator, Low-output negative ion generator
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- New York State Psychiatric Institute
Depression Disorders, Depression - Major Depressive Disorder
Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression
This project explores whether heated yoga, sauna, and a mindfulness app reduce depressive symptoms
- Conditions
- Depression Disorders, Depression - Major Depressive Disorder, Depression Disorder, Depression Chronic
- Trial name
- SHINE (NCT07082998)
- Testing
- heated yoga, sauna, mindfulness app
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Insomnia Chronic
Aerobic Exercise Versus Digital Cognitive Behavioral Therapy for Insomnia
The purpose of this study is to compare the effects of aerobic exercise versus digital CBT-I in university students with insomnia complaints. This is a clinical trial.
- Trial name
- NCT06636006
- Testing
- Aerobic Exercise, Cognitive Behavioral Therapy for Insomnia
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal de Goias
Chronic Obstr Lung Disease
Self-management Program in Patients With COPD
The prevalent, preventable, and treatable condition known as chronic obstructive pulmonary disease (COPD) is characterized by ongoing respiratory symptoms and restricted airflow caused by abnormalities of the airways and alveoli.
- Trial name
- NCT07068269
- Testing
- Self-Management Program, Routine Physical Therapy Exercises
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Back Pain Lower Back Chronic
MOTIVATE: Moving to Improve Outcomes for Older Adults
The overarching goal of this study is to evaluate a tele-based behavioral change intervention for older adults (aged 50 years and older) with chronic low back pain (cLBP) and comorbid depression, and to ultimately assess its…
- Trial name
- NCT03914469
- Testing
- Behavioral Intervention Group
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Texas Southwestern Medical Center
Major Depression, End Stage Renal Disease
Bupropion for Depression in ESRD Patients on Hemodialysis
The proposed study will evaluate the response and remission rates for major depressive disorder (MDD) in end-stage renal disease (ESRD) patients undergoing maintenance hemodialysis (HD) treated with bupropion or fluoxetine for 12…
- Trial name
- NCT02238977
- Testing
- Fluoxetine, Bupropion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Arkansas
Somatoform Disorders, Fibromyalgia
Immune Patterns in Pain Patients DSM-IV
The purpose of this study is to define subgroups of patients with somatoform disorders due to DSM-IV by immunological, psychological and genetic characterization.
- Conditions
- Somatoform Disorders, Fibromyalgia, Myofascial Pain Syndrome, Diffuse, Depression
- Trial name
- IPPPDIV (NCT01106339)
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Psychological Disorders, Hip Pain Chronic
The Differences in the Psychological States of Patients with Different Chronic Hip Pain
Nowadays, studies related to the psychological state of patients with chronic hip pain are still limited, and there is a lack of research on the characteristics of the psychological state of patients with chronic soreness from…
- Trial name
- NCT06611722
- Testing
- Psychological and Functional Assessment
- Where
- China
- Volunteers
- 70 people
- Sponsor
- ChunBao Li
Depression
Self-Management of Chronic Depressive Symptoms in Pregnancy
This study will provide information about the feasibility, acceptability, and preliminary effects of a biobehavioral self-management approach for perinatal depressive symptoms.
- Trial name
- NCT02953990
- Testing
- MOMS Program
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Virginia Commonwealth University
Rheumatoid Arthritis, Atherosclerotic Ischemic Disease
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that…
- Conditions
- Rheumatoid Arthritis, Atherosclerotic Ischemic Disease, Pulmonary Disease, Depressive Disorder
- Trial name
- COTIRA (NCT07363980)
- Where
- 4 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Ellen Margrethe Hauge
Medication Adherence, Medication Compliance
Connected Healthcare for Individuals Living at Home With Chronic Conditions
Managing and taking medications as prescribed can be a difficult task. This is especially true for older adults living at home with chronic conditions while managing multiple prescribed medications.
- Conditions
- Medication Adherence, Medication Compliance, Medication Nonadherence, Hypertension
- Trial name
- NCT04339296
- Testing
- Spencer
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Covid19, Chronic Kidney Diseases
Physical Activity Level in Patients with Chronic Kidney Disease During COVID-19 Pandemic
In the literature, there are no studies evaluating fear of COVID-19, anxiety, depression, physical activity, fear of movement and quality of life in patients with chronic kidney disease during COVID-19 pandemic.
- Trial name
- NCT04745923
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Depression, Chronic Disease
Group Self-Management of Depression and Medical Illness
This project addresses the important public health need to reduce ethnic disparities in depression care by pilot testing and refining a culturally tailored, low-cost intervention for improving both depression and general medical…
- Conditions
- Depression, Chronic Disease, Hispanic Americans
- Trial name
- NCT02017262
- Testing
- Self-management group, Enhanced usual care
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Southern California
Osteoarthritis, Knee
Positive Minds Strong Joints for Knee Osteoarthritis
The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).
- Trial name
- PMSJ (NCT06493903)
- Testing
- Positive Minds, Strong Joints
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Boston University Charles River Campus
Major Depressive Disorder, Hepatitis C, Chronic
Efficacy and Safety of Escitalopram for Prevention of Depression Induced by Peg-Interferon in Hepatitis C Patients
The purpose of this study is to determine whether the use of an antidepressant (escitalopram) can prevent depressive episodes that appear during the treatment with peg-interferon and ribavirin in patients with chronic hepatitis C.
- Trial name
- NCT00166296
- Testing
- Escitalopram
- Where
- 15 sites in Spain
- Volunteers
- 133 people
- Sponsor
- Germans Trias i Pujol Hospital
Chronic Pain
Mixed Reality-Based Rehabilitation Software for Chronic Secondary Musculoskeletal Pain
This study evaluated the efficacy and safety of a mixed reality-based chronic pain rehabilitation software (PK-MPT) for adults with chronic secondary musculoskeletal pain.
- Trial name
- NCT06936059
- Testing
- Mixed Reality based analgesic therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Emotional Distress
Mood Tracker Smartphone App for Management of Emotional Distress After TBI
Traumatic brain injury (TBI) is a common type of injury that affects thousands of people a year. TBI can cause a number of disabilities such as impaired cognition, decreased strength, decreased balance, problems controlling…
- Trial name
- NCT04410770
- Testing
- Mood tracker ratings
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Memorial Hermann Health System
Diabetes Mellitus, Congestive Heart Failure
Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1
The goal of this observational study is to describe the impacts of COVID-19 on primary care chronic condition management in Canada within various patient populations.
- Conditions
- Diabetes Mellitus, Congestive Heart Failure, Chronic Kidney Diseases, Chronic Obstructive Pulmonary Disease
- Trial name
- RIPPLE-C (NCT05813652)
- Testing
- Pre-pandemic time period (Jun 22, 2018 to March 12, 2020), Peri-pandemic time period (March 13, 2020 to December 3, 2021)
- Where
- Canada
- Volunteers
- 919,928 people
- Sponsor
- McMaster University
Chronic Pain
Evaluation of Alexithymia in Chronic Pain Patients With Spinal Cord Stimulation
The purpose of this study is to investigate the relationship between alexithymia levels and clinical parameters, including pain intensity and quality of life, in chronic pain patients treated with spinal cord stimulation (SCS).
- Trial name
- NCT07696286
- Testing
- Psychometric Questionnaires and Retrospective Data Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Marmara University
Post-acute Sequelae of COVID-19, Depressive Symptoms
Glutamatergic Modulation as a Treatment for Depressive Symptoms Among Patients With Post-acute Sequelae of COVID (PASC): A Pilot Trial
Post-acute sequelae of SARS-CoV2 (PASC), colloquially known as "long-COVID," is thought to affect between 10-30% of all COVID-19 survivors.
- Conditions
- Post-acute Sequelae of COVID-19, Depressive Symptoms, Cognitive Dysfunction
- Trial name
- NCT05690503
- Testing
- CI-581a, CI-581b
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- New York State Psychiatric Institute