Clinical trials: Depression Chronic
Stress, Generalized Anxiety
Enhancing Health in Rural Populations: Music as Therapy
The goal of this clinical trial is to learn whether a music-based intervention can improve mental and physical health and strengthen coping skills among adults living in residential care settings in northern Arizona.
- Conditions
- Stress, Generalized Anxiety, Chronic Pain, Depression Disorder
- Trial name
- NCT07538427
- Testing
- Music Based Intervention
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Stroke, Fatigue Syndrome, Chronic
Caregiver Burden and Psychological Outcomes in Caregivers of Stroke Patients With Lower Urinary Tract Symptoms
This cross-sectional observational study aims to evaluate caregiver burden, fatigue, sleep quality, and depression among family caregivers of stroke patients with lower urinary tract symptoms (LUTS).
- Conditions
- Stroke, Fatigue Syndrome, Chronic, Caregiver
- Trial name
- CARE-LUTS (NCT07480642)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Cardio-vascular Disease, Depression Disorders
Supporting Patients Starting New Medicines: Evaluating the myCare Start Service in Switzerland
In Phase B, the aim is to evaluate the myCare Start service in routine care within the ambulatory primary care medicine and community pharmacy setting in Switzerland.
- Conditions
- Cardio-vascular Disease, Depression Disorders, Diabetes, COPD
- Trial name
- myCare Start-I (NCT07036471)
- Testing
- myCare Start
- Where
- Switzerland
- Volunteers
- 1,600 people
- Sponsor
- University of Geneva, Switzerland
Chronic Pain, Post Traumatic Stress Disorder (PTSD)
Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain
The Veteran population has been known to deal with co-morbid chronic pain and PTSD. As a result, they use healthcare services at a higher rate than those Veterans with pain or PTSD alone which leads to an amplified burden on…
- Conditions
- Chronic Pain, Post Traumatic Stress Disorder (PTSD), Depression
- Trial name
- Warriors (NCT05254379)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Emory University
Chronic Disease
Theatre in Adolescents With Chronic Medical Conditions (CMCs)
Investigators are building a program that uses improvisation to teach kids and teens with medical issues healthy ways to cope. Medical issues have been linked to anxiety and depression.
- Trial name
- NCT05468788
- Testing
- Intervention: Integrative Community Therapy-based Psychodrama, Control: Improvisational Theatre
- Where
- United States
- Sponsor
- Geisinger Clinic
Benzodiazepine Adverse Reaction, Depression, Anxiety
Benzodiazepine Impact on Cognitive Function: fNIRs and PET/MRI Study
This study explores the impact of long-term benzodiazepine (BZDs) use on cognitive function and associated neuroimaging markers.
- Conditions
- Benzodiazepine Adverse Reaction, Depression, Anxiety, Benzodiazepine Dependence
- Trial name
- NCT06250842
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Depressive Disorder, Post-Acute COVID-19 Syndrome
IMPACT-D+: Immune-Modulating and Psychometric Effects of Accelerated TMS in Depression Plus Comorbid Post-COVID-19 Condition
This is a monocentric, randomized pilot study conducted at the Max Planck Institute of Psychiatry, Munich. The study investigates the effects of two different intermittent theta-burst stimulation (iTBS) schedules on biological…
- Trial name
- IMPACT-D+ (NCT07197138)
- Testing
- Intermittent theta-burst stimulation (iTBS) using PowerMAG 100 ppTMS
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Quality of Sleep, Subacute or Chronic Low Back Pain
Association Between Low Back Pain and Quality of Sleep
A prospective study to assess the association between the change in quality of sleep and the change in intensity of pain in Spanish patients seen for subacute or chronic low back pain.
- Conditions
- Quality of Sleep, Subacute or Chronic Low Back Pain, Disability, Catastrophizing
- Trial name
- NCT00906152
- Where
- 2 sites in Spain
- Volunteers
- 437 people
- Sponsor
- Kovacs Foundation
Chronic Hepatitis C
Prevention of Depression With Omega-3 Fatty Acids in Chronic Carriers of Hepatitis C Treated With Interferon Alpha.
The purpose of the study is to check whether development of depression as a side effect of interferon alpha treatment in chronic carriers of hepatitis C can be prevented by omega-3 fatty acids.
- Trial name
- NCT00408304
- Testing
- omega-3 fatty acid
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Chronic Insomnia
Brief Trial of ACT-i for Adults With Chronic Insomnia
This is a prospective, randomized-controlled trial that assesses the efficacy of a brief Acceptance and Commitment Therapy (ACT-i), compared to an attentional control group, in adults with chronic insomnia.
- Trial name
- NCT07048600
- Testing
- Acceptance and Commitment Therapy for Insomnia, Attentional Control Group
- Where
- Romania
- Volunteers
- 76 people
- Sponsor
- Babes-Bolyai University
Mental Health, Depression and Burden in Caregivers
SOS for Caregiver Wellbeing
Parents and caregivers of children who have a chronic condition carry a large care burden and are at higher risk of having mental health symptoms.
- Conditions
- Mental Health, Depression and Burden in Caregivers, Anxiety Depression, Stress
- Trial name
- SOS (NCT07136584)
- Testing
- Screening, Outcomes and Referral Pathways
- Where
- Australia
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
End Stage Renal Disease
The Routine Use of SSRI's at the Initiation of End-stage Renal Disease Treatment (RoSIE)
In this study the investigators hypothesize that antidepressant therapy may improve the overall welling of patients with acute or chronic kidney disease when given around the time of starting chronic dialysis therapy.
- Trial name
- RoSIE (NCT02407821)
- Testing
- Escitalopram
- Where
- 3 sites in Canada
- Volunteers
- 25 people
- Sponsor
- University Health Network, Toronto
Neck Pain Chronic, Depression Disorders
Effectiveness of Activity Oriented Therapy and Traditional Therapy in Cervical Discopathic Pain Syndrome
Title: Effectiveness of Activity Oriented Therapy and Traditional Therapy in Cervical Discopathic Pain Syndrome Procedures: You will be asked to complete a form containing questions characterizing the study group and several…
- Conditions
- Neck Pain Chronic, Depression Disorders, Forward Head Posture, Anxiety Disorders
- Trial name
- NCT06803264
- Testing
- Activity Oriented therapy (N.A.P.), Traditional therapy
- Where
- Poland
- Volunteers
- 74 people
- Sponsor
- University School of Physical Education, Krakow, Poland
Chronic Migraine, Medication Overuse Headache
Mindfulness Therapy for Chronic Migraine
The aim is to assess the efficacy of adding on a Mindfulness-based therapy to pharmacological prophylaxis (experimental group: pharmacological prophylaxis + Mindfulness) against pharmacological prophylaxis only (control group) on…
- Trial name
- Mind-CM (NCT03671681)
- Testing
- Mindfulness, Prophylactic
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Inflammatory Bowel Disease
Integrated Behavioral Health Innovations in Childhood Chronic Illness Care Delivery Systems
Study design: At baseline, all adolescents and young adults with IBD ages 12-21 years will be screened for anxiety and depression symptoms using the PHQ-9 and the Screen for Child Anxiety Related Disorders (SCARED) during a…
- Trial name
- NCT02740309
- Testing
- Integrated Brief Behavior Therapy (IBBT) Intervention, Treatment as usual
- Where
- United States
- Sponsor
- NYU Langone Health
Depression, Anxiety
The Mental Health Experiences of Sexual and Gender Minorities Living With Cancer and Their Care Partners
The purpose of this study is to examine relationships between contextual stressors and stress moderators, depression symptom experience, resilience, frailty, and quality of life among older sexual gender minorities cancer…
- Conditions
- Depression, Anxiety, Caregiver Burden, Stress
- Trial name
- SGMC (NCT05866705)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Fibromyalgia
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
Previous studies of intravenous ketamine, which is a non-competitive N-methyl-D aspartate receptor antagonist, for fibromyalgia pain relief are limited to three studies.
- Trial name
- NCT06916403
- Testing
- Intravenous Ketamine Infusions
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Wilderman Medical Clinic
Depression
Developing a Self-Management Program for People With Depression and Chronic Medical Illness
This study seeks to adapt an existing chronic disease self-management program for people with both chronic medical illness and depression.
- Trial name
- NCT00523029
- Testing
- Chronic Disease Self-Management Program
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Southern California