Clinical trials: Depression Chronic
Arthritis, Diabetes
Can Mental Health Chatbots Help Chronic Disease Populations?
Past research has shown that patients suffering from chronic health conditions tend to experience high levels of negative mental health symptoms (e.g., depression).
- Conditions
- Arthritis, Diabetes, Depression, Anxiety
- Trial name
- NCT04620668
- Testing
- Wysa
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Luke MacNeill
Chronic Pain, Anxiety
Phase II Trial of Nu-V3 Non-Invasive Nerve Stimulation Device for Chronic Pain, Anxiety, Depression, Sleeplessness
This Nu-V3 clinical study is a randomized, phase II, open-label study evaluating the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3P2RCT (NCT05394545)
- Testing
- Nu-V3
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nu-Life Solutions
Fibromyalgia
Vagus Nerve Stimulation for Treating Adults With Severe Fibromyalgia
Fibromyalgia syndrome (FMS) is a long-term disorder that is characterized by widespread body pain and tender points in joints, muscles, tendons, and other soft tissues.
- Trial name
- NCT00294281
- Testing
- Vagus Nerve Stimulation (VNS) Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Pain, Chronic, Pain, Pelvic
A Group Therapy Based on the Bio-psycho-social Treatment Approach for Women With Chronic Pelvic and Chronic Belly Pain
The project investigates the situation of patients with chronic pelvic and chronic belly pain before and after our group therapy.
- Conditions
- Pain, Chronic, Pain, Pelvic, Pain, Abdominal, Depression
- Trial name
- NCT04057664
- Testing
- Learning of Coping Strategies
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Chronic Kidney Disease, Depression
Chronic Kidney Disease Antidepressant Sertraline Trial
This is a randomized double-blinded placebo-controlled trial to see if treatment with sertraline as compared with placebo tablets will improve depression symptoms in patients with chronic kidney disease who have not yet started…
- Trial name
- CAST (NCT00946998)
- Testing
- Sertraline
- Where
- 2 sites in United States
- Volunteers
- 201 people
- Sponsor
- VA Office of Research and Development
Cognition, Affect (Mental Function)
BiomeBakery Project
This study aims to investigate the chronic effects of prebiotic fibre-fortified functional bakery product on cognitive, affective, inflammatory, metabolic, and anthropometric outcomes in healthy adults aged 60-75 years with mild…
- Conditions
- Cognition, Affect (Mental Function), C Reactive Protein
- Trial name
- NCT06796712
- Testing
- Prebiotic fibre fortified bread roll, Regular bread roll
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Reading
Major Depression, Generalized Anxiety Disorder
Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for Benzodiazepines
The hypothesis of this study is that symptoms of anxiety, depression and insomnia; and indices of psychosocial function will all improve, while BZ use will decrease significantly during a twelve-week trial period of substituting…
- Trial name
- NCT01244711
- Testing
- quetiapine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Weill Medical College of Cornell University
Depressive Symptoms, Multiple Chronic Conditions
Resourcefulness Intervention With Parents of Technology-Dependent Children
Technology-dependent children, those who live at home but rely on medical equipment such as mechanical ventilation or feeding tubes, require complex care for their chronic condition.
- Conditions
- Depressive Symptoms, Multiple Chronic Conditions, Family Caregivers
- Trial name
- NCT03301831
- Testing
- Resourcefulness Training
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Chronic Pain, Migraine Disability
Chronic Pain in the General Population of Chile
The present study seeks to follow up the cohort of adults representative of Chile's urban population whose levels of chronic pain were evaluated in March 2023 (baseline) as part of the Mental Health Thermometer (MHT) study.
- Conditions
- Chronic Pain, Migraine Disability, Neuropathic Pain, Fibromyalgia
- Trial name
- RDC (NCT06353100)
- Where
- Chile
- Volunteers
- 2,365 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Long COVID, Long COVID Syndrome
Evaluation of MicroRNAs and Vitamin B12 Expression in Subjects with Neurologic Symptoms of Depression, Anxiety and Fatigue in Long COVID-19
At the moment, the number of people with long COVID is unkown because there is still no effective diagnosis. This is why is very important to analyze the most common symptoms, which are: depression, anxiety and fatigue.
- Trial name
- NCT06864156
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Rehabilitacion
Heart Failure, Congestive, Chronic Heart Failure
Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure
This study will examine the effect of antidepressant medication on rates of death and disease in depressed people with chronic heart failure.
- Conditions
- Heart Failure, Congestive, Chronic Heart Failure, Depression
- Trial name
- SADHART-CHF (NCT00078286)
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 469 people
- Sponsor
- Duke University
Cirrhosis
Chronic Pain Optimization and Management for Relief and Functionality With TEA in Cirrhosis
This study is being done to better understand how the study team can treat pain for people with cirrhosis and depression. Enrolled participants on this feasibility study will be randomized to Transcutaneous Electrical…
- Trial name
- COMFORT (NCT07820917)
- Testing
- Transcutaneous Electrical Acustimulation (TEA)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Chronic Pain, Depression, Anxiety
Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications
The investigators are conducting a comparative effectiveness trial among adult patients with sickle cell disease (SCD) who report chronic pain (N = 350), randomized to receive either mobile phone-delivered computerized cognitive…
- Conditions
- Chronic Pain, Depression, Anxiety, Opioid Use
- Trial name
- CaRISMA (NCT04419168)
- Testing
- cCBT, m-Education
- Where
- 7 sites in United States
- Volunteers
- 359 people
- Sponsor
- University of Pittsburgh
Chronic Pain, Major Depressive Disorder
The Internet Therapy for Depression Trial
The objective of this trial is to collect data on the feasibility, acceptability, and preliminary effectiveness of internet delivered Cognitive Beaviour Therapy (iCBT) and Acceptance and Commitment Therapy (iACT) interventions…
- Trial name
- INTEREST (NCT04009135)
- Testing
- internet delivered cognitive behavioural therapy (iCBT), online delivered acceptance and commitment therapy (iACT), Attention Control (AC)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Memorial University of Newfoundland
Depressive Disorder, Treatment-Resistant, Stress Disorders, Post-Traumatic
Ketamine Infusions for PTSD and Treatment-Resistant Depression
The relationship between depression and trauma is well established. Co-occuring depression and post-traumatic stress disorder (PTSD) are associated with more severe symptoms and lower levels of functioning.
- Trial name
- NCT02577250
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Chronic Obstructive Pulmonary Disease
Physical Activity Promotion Added to Standard Care Pulmonary Rehabilitation and Cognitive Behavioural Therapy
In patients with Chronic Obstructive Pulmonary Disease (COPD) daily physical activity is reduced compared to healthy age-matched individuals.
- Trial name
- NCT03749655
- Testing
- Physical Activity Promotion
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Northumbria University
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Pain
Descriptive Study of Pain, Anxiety and Depression
The purpose of the study is to investigate pain, anxiety and depression in chronic pain patients with and without neuropathic pain compared with healthy volunteers
- Trial name
- NCT00378274
- Testing
- Observation
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Depression in Adolescence, Depressive Disorder
Clinical Effectiveness of TARA Compared to Standard Treatment for Adolescents and Young Adults With Depression
Depressive Disorders constitute an increasing global health concern and available treatments for young people have not been sufficiently effective in haltering this trend.
- Conditions
- Depression in Adolescence, Depressive Disorder, Dysthymia and Chronic Depression
- Trial name
- TARA (NCT04747340)
- Testing
- Training for Awareness Resilience and Action (TARA), Standard treatment
- Where
- 3 sites in Sweden
- Volunteers
- 136 people
- Sponsor
- Umeå University
Chronic Pain, Mental Health Disorder
Therapeutic Writing for Adults Suffering From Chronic Pain and Comorbid Mental Health Disorders
The goal of this observational study is to understand the effects and experiences of therapeutic writing interventions in adult women with chronic pain and co-occurring mental health conditions.
- Conditions
- Chronic Pain, Mental Health Disorder, Psychiatric &Amp;Amp;or Mood Disorder, Psychiatric Comorbidities
- Trial name
- TWfCP&MH (NCT07058532)
- Testing
- Therapeutic Writing Intervention in Pain Rehabilitation
- Where
- Finland
- Sponsor
- Toni Salikka