Clinical trials: Depression Diagnosis
Major Depressive Disorder
Long-Term Follow Up Study
The LTFU study will conduct a naturalistic follow up of the well characterized CAN-BIND study population of patients every six months and continuing over a five-year period.
- Trial name
- CAN-BIND LTFU (NCT02998762)
- Where
- 5 sites in Canada
- Volunteers
- 96 people
- Sponsor
- Sidney Kennedy
Sleep Phase Rhythm Disturbance, Sleep Deprivation
Are Bright Lights and Regulated Sleep Effective Treatment for Depression?
Previous data suggest some depressed patients act as if their internal biological clock is out of sync with the outside world and re-aligning their clock with the timing of sunlight lessens their depressed mood and accompanying…
- Trial name
- NCT03010488
- Testing
- Morning Light Therapy, Assigned Sleep Times, Goggles
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- New York State Psychiatric Institute
Major Depression
Discontinuation Study Of Citalopram (Antidepressant) in Depressed Adolescents
The purpose of the study is to evaluate whether it is advantageous for adolescents who have recovered from depression after a 6 to 12 week course of antidepressant treatment to stay on the treatment a further 6 months or is it…
- Trial name
- NCT00249886
- Testing
- Citalopram
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Major Depression
Evaluation of the H-Coil Transcranial Magnetic Stimulation(TMS) Device- Augmentation for Drug Resistant Depression
There is a general consensus of efficacy of TMS in treatment of major depression,yet results are not satisfying.A new coil ("H"-coil, recently invented in Weizmann Institute of Science, Neurobiology Department, Rehovot, Israel)…
- Trial name
- NCT00577070
- Testing
- TMS
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- BeerYaakov Mental Health Center
Perinatal Anxiety, Perinatal Depression
Pathways to Perinatal Mental Health Equity
Mental health conditions occurring during pregnancy and up to one year postpartum (the perinatal period) occur in 1 in 5 perinatal individuals.
- Conditions
- Perinatal Anxiety, Perinatal Depression, Social Determinants of Health (SDOH), Peer Support
- Trial name
- Pathways (NCT06790641)
- Testing
- Program in Support of Moms (PRISM), PSI Peer Support
- Where
- United States
- Volunteers
- 1,270 people
- Sponsor
- University of Massachusetts, Worcester
Heart Rate Variability
Impact of Community-Based Biofeedback Program on Drug Use and Mental Health Among People Experiencing Homelessness
The purpose of this randomized controlled trial was to compare the effectiveness of an HRV-BF intervention versus a health promotion active control intervention focused on improving mental health symptoms among people…
- Trial name
- HRV-BF (NCT05897580)
- Testing
- Heart Rate Variability - Biofeedback (HRV-BF), Health Promotion (HP)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of California, Irvine
Emotional Well-being
iCBT to Promote Emotional Well-being in University and Research Communities: Feasibility and Acceptability Study
This study will evaluate a brief internet-based cognitive behavioral therapy (iCBT) program developed specifically for university students, researchers, and academic staff.
- Trial name
- iCBT-Academia (NCT07082296)
- Testing
- iCBT-Academia
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Joaquim Radua
Major Depression Severe
Ayahuasca and Esketamine for Major Depression
Double-blind, randomized trial comparing 4 weekly doses of oral ayahuasca and esketamine in patients with major depression.
- Trial name
- NCT07212946
- Testing
- Ayahuasca, Esketamine
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo
Major Depressive Disorder
The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients
Vildagliptin, an antidiabetic drug that inhibits the dipeptidyl peptidase- 4 (DPP-4), increases glucagon-like peptide-1 (GLP-1) and regulates blood glucose levels, favoring weight loss and lowering cardiovascular risk.
- Trial name
- NCT04410341
- Testing
- Vildagliptin 50 MG, Escitalopram 20 mg
- Where
- Egypt
- Sponsor
- Sadat City University
Depression, Late Life Mood Disorder
A Study on Better Cognitive Functioning Through Braintraining on the Internet
This study evaluates the efficacy of an eight-week online cognitive training program on feasability and on objective and subjective cognitive functions in patients with late life mood disorders (LLMD).
- Conditions
- Depression, Late Life Mood Disorder, Impaired Cognition, Alteration in Mood
- Trial name
- BrainFit (NCT04006756)
- Testing
- Online cognitive training 1, Online cognitive training 2
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Amsterdam UMC, location VUmc
Major Depressive Disorder, Soft Tissue Discomfort Syndrome
Functional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort Syndrome
The objective of this study is to determine the time course of duloxetine efficacy on the symptoms of Major Depressive Disorder (MDD)and on the symptoms of Soft Tissue Discomfort Syndrome(STDS) via use of 24-hour Actigraph™…
- Conditions
- Major Depressive Disorder, Soft Tissue Discomfort Syndrome, Pain
- Trial name
- NCT01035073
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pennsylvania
Depression, Anxiety
Mechanisms of Anxiety and Depression Study
Eligible participants will come in for three separate visits in which they will be interviewed, perform a variety of tasks, and undergo a non-invasive MRI scan.
- Trial name
- NCT03135756
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Palo Alto University
Depression, Anxiety
A Pychoeducational Intervention for Women With Diabetes
This proposal describes a small randomized study to determine whether usual medical care (UMC) for diabetes combined with a psychoeducational program is more effective than UMC for diabetes alone.
- Conditions
- Depression, Anxiety, Anger
- Trial name
- SWEEP (NCT01185561)
- Testing
- Psychoeducational intervention
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Loyola University
PreDiabetes, Physical Inactivity
The Effect of Exercise on Quality of Life, Sleep Quality and Anxiety in Patients With Prediabetes (EFEXQULS)
The aim of this study is to determine the effect of exercise on quality of life, sleep quality and anxiety in patients with prediabetes.
- Conditions
- PreDiabetes, Physical Inactivity, Quality of Life, Sleep
- Trial name
- EFEXQULS (NCT05147883)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
TMS Protocols in the Treatment of PD
Standardization and Optimization of TMS Protocols for the Treatment of PD With Depression or Cognitive Impairment
The goal of this study is to determine whether transcranial magnetic stimulation (TMS) is an effective treatment in Parkinson's disease patients with depression or cognitive impairment.
- Trial name
- NCT03552861
- Testing
- repetitive transcranial magnetic stimulation(rTMS)
- Where
- 10 sites in China
- Volunteers
- 252 people
- Sponsor
- Guangdong Provincial People's Hospital
Postoperative Pain, Postpartum Depression
Dose Low Dose Ketamine in Casesarian
The results of ketamine, ketamine and midazolom can be copied after birth in cesareans subjected to spinal anesthesia.
- Trial name
- ketamine (NCT06237569)
- Testing
- Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
Alzheimer s Disease, Dementia
CommunityRx-Dementia + Peer Navigation (CRxDpeer)
The CRxDpeer intervention, delivered by a trained peer navigator, in practice called a "peer mentor", includes three evidence-based components: (a) focused education about common social (e.g., food and housing insecurity) and…
- Conditions
- Alzheimer s Disease, Dementia, Caregiver, Loneliness
- Trial name
- CRxDpeer (NCT07346183)
- Testing
- CommunityRx-Dpeer
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Bipolar Disorder
Radiosurgical Neuromodulation for Refractory Depression
This study is designed to evaluate the safety and effectiveness of an investigational procedure for treating people with treatment resistant bipolar depression (TRD).
- Trial name
- NCT01403441
- Testing
- Radiosurgical Neuromodulation using the Cyberknife
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Depression, Sleep Disturbance
Smart Light Therapy Glasses for Sleep and Mental Wellness
A pair of smart light therapy glasses (Lumos Glasses) was engineered to control the amount of blue light exposure at a person's eyes through a battery powered light source and nano-coating that reflect blue light.
- Trial name
- NCT07168954
- Testing
- Lumos Glasses
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Opioid-use Disorder, Addiction
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
- Trial name
- CLARO (NCT04559893)
- Testing
- Collaborative Care
- Where
- 16 sites in United States
- Volunteers
- 729 people
- Sponsor
- RAND
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