Clinical trials: Depression Diagnosis
Depression, Anxiety, Anger
Building Emotional Awareness and Mental Health (BEAM) 2024-2027
Children are highly sensitive to adversity during their first five years of life, with exposure to chronic parental mental illness (MI) consistently linked to socio-emotional impairments and mental health problems in children.
- Conditions
- Depression, Anxiety, Anger, Parenting, Stress, Psychological
- Trial name
- BEAM (NCT06455397)
- Testing
- The Building Emotional Awareness and Mental Health (BEAM) Program
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Leslie E. Roos
Anxiety Disorders, Depressive Disorders
Antidepressant Safety in Kids Study
This study will evaluate the risks and benefits of treatment with a selective serotonin reuptake inhibitor or serotonin-norepinephrine reuptake inhibitor in children and adolescents with a pre-specified anxiety disorder…
- Conditions
- Anxiety Disorders, Depressive Disorders, Eating Disorders, Obsessive Compulsive Disorder
- Trial name
- ASK (NCT00395213)
- Testing
- Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) medications
- Where
- United States
- Volunteers
- 569 people
- Sponsor
- Duke University
Depression
Assessment of Stress, Depression and Anxiety in Healthcare Caring for Patients With COVID-19
Medical personnel working in the Intensive Care Unit will be examined by means of tests. Their aim is to check how work-related stress in a potentially lethal threat affects the occurrence of depression, stress, anxiety and sleep…
- Trial name
- NCT04631497
- Testing
- test
- Where
- Poland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Bipolar Disorder
ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder
The goal of this clinical trial is to test the efficacy of Acceptance and Commitment Therapy (ACT) as a psychotherapeutic treatment for patients with Bipolar Disorder (BD).
- Trial name
- NCT06365021
- Testing
- Acceptance and Commitment Therapy, Bipolar Disorder Psychoeducation Therapy
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Beny Lafer
Major Depressive Disorder
Sumor as Adjuvant Therapy in Treatment-resistant Major Depression
Sumor is a food supplement that combines the main coenzymes of the S-Adenosyl methionine (SAMe) cycle, namely vitamins B6, B12 and folate, with SAMe and betaine.
- Trial name
- SUSCA (NCT04832178)
- Testing
- SUMOR
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Bipolar Disorder
Effect of Quetiapine on Sleep Architecture in Bipolar Depression and Major Depressive Disorder
Clinical practice indicates that Quetiapine has sedating properties, and its sedative effects may play an important role in restoring quality of sleep in patients with various psychiatric conditions who frequently experience…
- Trial name
- NCT00616889
- Testing
- Seroquel
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Queen's University
Depressive Disorder, Major
Neuropsychological Factors Associated With Vulnerability to Suicidal Behavior in Depressed Elderly Patients
The main objective of this study is to confirm the existence of risky decision making in a non strategic situation (Iowa Gambling Task) and a deficit of decision making in social situations, linked to greater sensitivity to…
- Trial name
- SPAD (NCT02737540)
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Depressive Disorder, Major Depressive Disorder, Healthy Volunteer
Exploring the Role of the Prefrontal Cortex in Decision-Making
The goal of this study is to examine whether high-definition transcranial direct current stimulation (HD-tDCS) can influence decision-making for emotionally valenced content in younger and older adults, with or without major…
- Conditions
- Depressive Disorder, Major Depressive Disorder, Healthy Volunteer, Aging
- Trial name
- NCT07080489
- Testing
- Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/F4, Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/ kathodal F4
- Where
- Switzerland
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- University of Bern
Anxiety, Depression
Risk Factors of Psychiatric Disorders and Sexual Dysfunction in Infertile Men
To investigate the prevalence of psychological symptoms and sexual dysfunction, and to estimate their possible interactions in infertile men.
- Conditions
- Anxiety, Depression, Sexual Dysfunction, Infertility
- Trial name
- NCT01893216
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Major Depressive Disorder, Bipolar Disorder
Behavioral Processes Underlying Reward Processing in Depression
The purpose of this project is to use behavioral techniques to investigate emotional processing in subjects with major depression and healthy comparison subjects.
- Trial name
- NCT00205933
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Affective Neuroscience Laboratory
Pregnancy, High Risk, Child Development
Nurse Family Partnership for Women With Previous Live Births
The goal of this clinical trial is to test the Nurse Family Partnership (NFP) in mothers with previous live births (multiparous or multip individuals).
- Conditions
- Pregnancy, High Risk, Child Development, Post Partum Depression
- Trial name
- NCT05887115
- Testing
- Nurse Family Partnership
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depression Disorders, Anxiety Disorders
Validate the Temporal Stability and Responsiveness of AI-COA® for Depression and Anxiety
This study evaluates the reliability and responsiveness of the AI-COA®, a digital tool designed to assess the severity of depression and anxiety.
- Trial name
- SEQUOIA-2 (NCT07279025)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Deliberate Solutions Inc.
Major Depressive Disorder, Unipolar Depression
Portable Transcranial Electrical Stimulation and Internet-Based Behavioral Therapy for Major Depression Study
First-line treatments for major depressive disorder (MDD), antidepressants and psychotherapy, are associated with refractoriness and discontinuation due to side effects, and logistical burdens, respectively.
- Trial name
- PSYLECT (NCT04889976)
- Testing
- Double Active: Active portable transcranial stimulation (ptES) and active internet-based behavioral therapy (iBT)
- Where
- 2 sites in Brazil
- Volunteers
- 210 people
- Sponsor
- University of Sao Paulo
Depressive Disorder
An Eight-Week Study Evaluating the Efficacy of Two Fixed Doses (250 mg Twice Daily and 100 mg Twice Daily) of SSR149415 in Patients With Major Depressive Disorder
The purpose of the study is to evaluate the efficacy of SSR149415 in the treatment of Major Depressive Disorder, defined as a change from baseline to visit 7 in the Hamilton Depression Rating Scale.
- Trial name
- LENA (NCT00361491)
- Testing
- SSR149415
- Where
- 7 sites in Argentina, Bulgaria and 5 more
- Volunteers
- 324 people
- Sponsor
- Sanofi
Stress Disorders, Post-Traumatic, Depression
Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation - Effects on PTSD
Through many years, the standard care has been to use continuous sedation of critically ill patients during mechanical ventilation.
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety
- Trial name
- NCT02040649
- Testing
- Non-sedation, Control, sedation (propofol, midazolam)
- Where
- Denmark
- Volunteers
- 205 people
- Sponsor
- Palle Toft
Traumatic Brain Injury (TBI) Patients, Cognitive Impairment
Mindfulness-Integrated Neuropsychotherapy for Traumatic Brain Injury: A Mixed-Methods Evaluation of Cognitive and Psychosocial Recovery
The goal of this clinical trial is to test the effectiveness of Integrative Mindfulness Enhanced Neuropsychotherapy (IMENP) in improving neurocognitive functioning and wellbeing among adults aged 18 to 44 years with mild to…
- Conditions
- Traumatic Brain Injury (TBI) Patients, Cognitive Impairment, Depression Disorder, Fatigue Severity Scale
- Trial name
- IMENP (NCT07874685)
- Testing
- Integrative Mindfulness Enhanced Neuropsychotherapy (IMENP)
- Where
- India
- Volunteers
- 68 people
- Sponsor
- University of Madras
Depressive Disorder, Treatment-Resistant, Memory Deficits
SAINT® Therapy for Memory Problems in Older Adults With Treatment-Resistant Depression
The goal of this clinical trial is to learn whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT®), a type of transcranial magnetic stimulation (TMS), is safe and may improve memory and thinking in adults aged…
- Trial name
- NCT07876908
- Testing
- Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT®) with the Magnus Neuromodulation System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BrainHealth Solutions, Inc.
Pain, Insomnia
Effect of Medical Marijuana on Neurocognition and Escalation of Use
This study will use a randomized controlled design to test whether patients who use medical marijuana, compared to a waitlist control group, experience a change in health outcomes (relief of symptoms, or adverse health outcomes…
- Conditions
- Pain, Insomnia, Depression, Anxiety
- Trial name
- MMNE (NCT03224468)
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
MDD, Major Depressive Disorder
rTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFS
To explore the effectiveness and safety of rTMS intervention with different targets in the left prefrontal cortex defined using the pBFS method, in adult patients with moderate and severe depressive disorder.
- Conditions
- MDD, Major Depressive Disorder, Treatment Resistant Depression
- Trial name
- NCT06095778
- Testing
- active rTMS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Changping Laboratory
Traumatic Brain Injury (TBI) Patients
Transcutaneous Vagus Nerve Stimulation for Attention and Memory
This clinical trial aims to evaluate whether transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive brain stimulation method, can improve attention and memory in veterans with traumatic brain injury (TBI) and…
- Trial name
- taVNS (NCT06723743)
- Testing
- Transcutaneous vagus nerve stimulation for attention in veterans with TBI, Soterix Medical Vagus Nerve Stimulation mini-CT
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
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