Clinical trials: Depression Diagnosis
Suicide, Depressive Disorder, Major
Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide
This research study is designed to answer specific questions about new ways to provide services for youth at-risk of suicide.
- Conditions
- Suicide, Depressive Disorder, Major, Anxiety Disorders, Suicidal Ideation
- Trial name
- PASS (NCT03016572)
- Testing
- Standard of Care, Crisis Intervention, Wraparound Services
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Cleveland Clinic
Major Depression
Duke Conte Center for the Neuroscience of Depression in Late Life
The proposed Silvio O. Conte Center for Neuroscience of Depression will focus on understanding the neurobiological mechanism of depression. A total of 5 projects are proposed. The center is focused on a single hypothesis.
- Trial name
- NCT00576875
- Where
- United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Duke University
Major Depressive Disorder (MDD)
Scopolamine in Healthy Volunteers
This single-site clinical trial is an open-label study to identify the safety and pharmacokinetics of DPI-386 Nasal Gel (intranasal scopolamine gel) and IV Scopolamine.
- Trial name
- NCT03874130
- Testing
- Scopolamine
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Depression, Fatigue
Depression and Interleukin-6 Production in Patients With Ovarian Epithelial Cancer
RATIONALE: Measuring levels of interleukin-6 and depression may help doctors understand the relationship between interleukin-6 and depression. It may also help the study of cancer in the future.
- Conditions
- Depression, Fatigue, Ovarian Cancer, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00460200
- Testing
- polymorphism analysis, laboratory biomarker analysis, physiologic testing
- Sponsor
- Jonsson Comprehensive Cancer Center
Major Depressive Disorder
The BIomarker Guided (BIG) Study for Depression
Cognitive impairments contribute significantly to psychosocial dysfunction in major depressive disorder (MDD) and respond poorly to conventional antidepressants, yet selective treatments targeted to these impairments are lacking.
- Trial name
- NCT04181736
- Testing
- Guanfacine Tablets
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Major Depressive Disorder, Post-Traumatic Stress Disorder
Examination of Glutamate and mGluR5 in Psychiatric Disorders
This research study is designed to look at the involvement of the glutamate system in depression. Each subject will undergo a screening appointment to determine study eligibility.
- Conditions
- Major Depressive Disorder, Post-Traumatic Stress Disorder, Bipolar Disorder
- Trial name
- NCT02727972
- Testing
- Cognitive Testing, MRI, PET
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Mental Health, Depression
Viome Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions
US residents who have mental health issues sign the informed consent form and are screened and enrolled for this study. Participants who are enrolled complete a survey upon enrollment and are randomized into one of three arms.
- Conditions
- Mental Health, Depression, Anxiety
- Trial name
- NCT05563857
- Testing
- VIOME Precision Nutrition Program, VIOME-designed condition-based supplements
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Viome
Major Depressive Disorder (MDD)
A Clinical Trial of Add-on Oral Slow-release Ketamine Treatment in Major Depression
The goal of this clinical trial is to explore if the treatment with ketamine tablets in addition to standard antidepressant therapy can reduce depressive symptoms in adults with Major Depressive Disorder.
- Trial name
- KET01-IIT03 (NCT07396272)
- Testing
- Treatment with Ketamine Hydrochloride Prolonged-Release Tablets
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Daniel Lindqvist
Anxiety, Mood Disorders
Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings
This Phase II trial will examine engagement in telehealth for children undergoing psychotherapy. Specifically, the trial will examine patient engagement in Teleo, a virtual therapy platform specifically designed for psychotherapy…
- Trial name
- NCT07155707
- Testing
- Teleo, Standard Videoconferencing
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Stanford University
ADHD, Depression
Does Cultivating Self-compassion Improve Resilience to Criticism and Improve Mental Health in Adults With ADHD?
This study aims to investigate the effect that increasing levels of self-compassion may have on levels of perceived criticism, self-criticism, and mental health of adults with ADHD.
- Conditions
- ADHD, Depression, Stress, Self-Criticism
- Trial name
- NCT04978792
- Testing
- Online self-compassion intervention, Active Control
- Where
- United Kingdom
- Volunteers
- 114 people
- Sponsor
- University of Sheffield
Bipolar Depression
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I or bipolar II disorder as…
- Trial name
- NCT06372964
- Testing
- Lumateperone
- Where
- 68 sites in United States, Colombia and 2 more
- Volunteers
- 384 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder:Knowledge,Attitude and Practice Among Egyptian Females
it is a cross-sectional study conducted in female patients attending outpatient clinc in our university hospital to assess their awareness regarding the symptoms of premenstrual dysphoric disorders.
- Trial name
- PMDD (NCT05327075)
- Testing
- questionnaire
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Al-Azhar University
Parkinson's Disease, Depression
Cognitive Behavioral Therapy for Depression in Parkinson's Disease
The purpose of this pilot program is to develop and evaluate a new treatment program for depression in Parkinson's disease (PD).
- Trial name
- NCT00810628
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Oregon Health and Science University
Psychiatric Nursing, Depression Disorder
The Effect of Psychodrama-Based Group Work
Aims This study examined the effect of psychodrama-based group work on postpartum women's tendencies toward depression and forgiveness.
- Conditions
- Psychiatric Nursing, Depression Disorder, Forgiveness, Puerperal Depression
- Trial name
- NCT07305571
- Testing
- psychodrama-based group intervention, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Ömer USLU
Insomnia, Depression
Internet-CBT for Insomnia
This study includes two sub-trials. In trial 1 patients suffering from insomnia but not meeting the criteria for depression are randomised to either therapist guided Internet-based CBT for insomnia or to a control group with a…
- Trial name
- IpsyInsomni (NCT01256099)
- Testing
- Therapist guided Internet-CBT for insomnia, Brief Internet-CBT for insomnia, without support, Therapist Guided Internet-CBT for depression
- Where
- Sweden
- Volunteers
- 191 people
- Sponsor
- Karolinska Institutet
Depression
Predicting Effectiveness of Light Treatment for Winter Seasonal Affective Disorder
This study will evaluate a possible tool for predicting future effectiveness of bright light in treating seasonal affective disorder, winter subtype, and will examine secondary effects of bright light on cardiovascular risk…
- Trial name
- NCT00742365
- Testing
- Bright light
- Volunteers
- 41 people
- Sponsor
- University of Maryland, Baltimore
Mild Cognitive Impairment, Subthreshold Depression
A One-year Trajectory of Depression Status Changes in Older Adults With MCI and SD: a Longitudinal Cohort Study
The purpose of this study is to investigate the one-year trajectory of changes in depression status in older adults with mild cognitive impairment and subthreshold depression, and to explore relevant risk factors for predicting…
- Conditions
- Mild Cognitive Impairment, Subthreshold Depression, Older Adults
- Trial name
- NCT06308627
- Where
- China
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Quality of Life (QOL), Depression
Body-Mind-Spirit Action Group on the Well-being
Primary Purpose: To evaluate the effectiveness of a culturally adapted BMS group intervention on holistic well-being, depressive symptoms, sleep parameters, and quality of life in individuals with visual impairment.
- Trial name
- BMS (NCT07105761)
- Testing
- Body-Mind-Spirit
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taipei City Hospital
Major Depressive Disorder, General Anxiety Disorder
Emotional Brain Networks & Cognitive Functioning in Depression and Anxiety
This study aims to 1) examine common and specific emotional and cognitive dysfunctions between Major Depression and generalized anxiety disorder; 2) Examine emotional and cognitive dysfunctions between the two disorders and…
- Trial name
- NCT03084042
- Testing
- fMRI
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Depressive Disorder, Major
Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD)
The study will evaluate the efficacy, safety, and tolerability of 450 milligrams (mg) of Rapastinel, compared to 10 mg of Vortixetine and placebo in participants with major depressive disorder (MDD).
- Trial name
- NCT03855865
- Testing
- Rapastinel, Vortioxetine
- Sponsor
- Naurex, Inc, an affiliate of Allergan plc
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