Clinical trials: Depression Symptom
Anxiety, Depression
Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students
Background and Study Aims: Secondary school students are reporting unprecedented levels of anxiety and mood difficulties. To ensure that the needs of all young people are met, there is a need to evaluate more accessible forms of…
- Conditions
- Anxiety, Depression, Internalizing Problems, Low Mood
- Trial name
- NCT06188962
- Testing
- CBT-informed school-based counselling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Major Depressive Disorder
Accelerated Treatment of Depressive Patients With tDCS
A randomized, controlled three-arm study is planned to investigate the effectiveness and feasibility of an accelerated home-based tDCS application (3 weeks of transcranial direct current stimulation at home, twice daily).
- Trial name
- AcctDCS (NCT07444242)
- Testing
- Transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Regensburg
Idiopathic Normal Pressure Hydrocephalus
Gait Pattern and Experienced Global Change After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Part 1 Patients with idiopathic Normal Pressure Hydrocephalus (iNPH) have variable disabilities regarding gait, balance, cognition and continence.
- Trial name
- NCT04795089
- Testing
- Shunt surgery
- Where
- Sweden
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Laryngeal Carcinoma, Quality of Life (QOL)
Quality of Life and Functional Outcomes in Laryngeal Cancer Patients
Laryngeal squamous cell carcinomas are head and neck malignancies that directly affect both swallowing and voice functions and are associated with a significant deterioration in patients' quality of life throughout the treatment…
- Conditions
- Laryngeal Carcinoma, Quality of Life (QOL), Patient Satisfaction, Voice Quality
- Trial name
- QoL in LSSC (NCT07320820)
- Testing
- Quality of Life Assessment, Patient Satisfaction Assessment, Swallowing Function Assessment
- Volunteers
- 120 people
- Sponsor
- Saglik Bilimleri Universitesi
Depression
Effectiveness and Dissemination of Computer-based Cognitive Behavioral Therapy and Online Stress Management Program for Adolescents
The aim of this study is to investigate the effectiveness of a computer-based Cognitive Behavioral Therapy (CCBT) and online stress management program for adolescents, and identify the characteristics of depressed adolescents…
- Trial name
- NCT04957680
- Testing
- CCBT
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul National University Hospital
Addiction, Depression/Anxiety
Healing Lodge First Face Training Evaluation Study
The purpose of this study is to evaluate a culturally grounded training program, xaʔtus (meaning First Face) for Mental Health. This program will train community members in how to recognize and respond to youth and adults…
- Conditions
- Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
- Trial name
- NCT06290180
- Testing
- First Face for Mental Heatlh
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Sensory Processing Sensitivity
Mindfulness-Based Stress Reduction (MBSR) for People High on the Personality Trait Sensory Processing Sensitivity: A Mixed Methods Study
This study investigates the efficacy of MBSR training in alleviating stress-related symptoms among individuals with high sensory processing sensitivity.
- Trial name
- MindSens (NCT06390020)
- Testing
- MBSR
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- Radboud University Medical Center
Anxiety, Depression
A Prospective and Experimental Study on the Effect of One-Day of Acceptance and Commitment Therapy (ACT) on Psychological Flexibility, Psychological Capital, Anxiety and Depression Among Undergraduate Students.
The goal of this study is to examine the effect of a one-day ACT intervention on psychological flexibility and psychological capital among undergraduate students at UTM who have anxiety and depression.
- Trial name
- ACT (NCT06832462)
- Testing
- Acceptance and Commitment Therapy
- Where
- Malaysia
- Volunteers
- 61 people
- Sponsor
- Universiti Teknologi Malaysia
Stroke, Depressive Symptoms
The Effect of Instant Message Intervention for Psychological Well-being Among Stroke Survivors
The proposed pilot trial aims to evaluate the feasibility of iCBT based EMI, which is a real-time, real-world, personalised and cost-effective approach, for stroke survivors' psychological well-being.
- Conditions
- Stroke, Depressive Symptoms, Mobile Phone Use
- Trial name
- NCT05490069
- Testing
- iCBT-based EMI
- Where
- 7 sites in Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Postoperative Pain, Acute, Postoperative Depression
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
The purpose of this research study is to learn how two different supportive programs may help women feel better after surgery. This study will measure if one type of supportive program is more useful than the other for improving…
- Conditions
- Postoperative Pain, Acute, Postoperative Depression, Anxiety, Sleep Disturbance
- Trial name
- NCT05625360
- Testing
- eHealth Mindful Movement and Breathing, Life Impacts Reflection, PROMIS Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Major Depressive Disorder (MDD), Suicidal Ideation
Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk
The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts.
- Trial name
- NCT07025720
- Testing
- TMS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Mental Health Issue
The Effect of Increasing Physical Activity or Reducing Mobile Phone Use on Mental Health in Young People in Austria
Introduction: Data show adolescent mental health has declined in recent years, possibly due to increased uncertainty and loss of opportunities.
- Trial name
- SPARKY (NCT06153524)
- Testing
- Physical activity, Smartphone time
- Where
- Austria
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Suicide
Impairment of the Cognitive Flow in the Development of a Depressive Disorder and Suicidal Ideas
The study consists in estimating the mental load (cognitive saturation) and the production of driving cognition to suicidal patients.
- Trial name
- AQUARIUM (NCT03674580)
- Testing
- Follow-up of the suicidal patients
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Hôpital NOVO
Chronic Pancreatitis
Fatigue, Psychological Comorbidity and Quality of Life Among Patients With Chronic Pancreatitis in China.
This study will investigate the status of fatigue, psychological comorbidity and quality of life among patients with chronic pancreatitis in China and analyze their influencing factors.
- Trial name
- NCT05489003
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Depression, Subclinical Depressive Symptoms
Cognitive Training Video Game to Target Subclinical Depressive Symptoms in Youth
The purpose of the study is to determine how cognitive control training (CCT) changes behavior in youth with subclinical depressive symptoms.
- Trial name
- NCT05697627
- Testing
- Computerized cognitive training (CCT) using EndeavorRx
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Michigan
Depression
Step Away From Depression - Evaluation of a Pedometer Intervention With Inpatients With Major Depression
The purpose of this study is to determine if the use of pedometers can help depressive inpatients in psychiatric clinics to increase their level of physical activity.
- Trial name
- SAD (NCT02850341)
- Testing
- Pedometer
- Where
- 9 sites in Austria, Germany
- Volunteers
- 292 people
- Sponsor
- Charite University, Berlin, Germany
Mild to Moderate Depression
Pilot Study Using Transcranial Electrostimulation (TESA-HB) Therapy for the Treatment of Depressive Symptoms
This pilot study uses TESA-HB therapy for treatment of depressive symptoms associated with mild and moderate depression episodes.
- Trial name
- TESAHBPilot (NCT03471754)
- Testing
- TESA-HB Transcranial Electronic Stimulation Device
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Annecto LLC
Pain, Depression
Virtual Reality Effect in Geriatric Individuals
This study aimed to determine the effect of a virtual reality experience on pain, depression and functional adequacy in geriatric individuals living in a nursing home.
- Trial name
- NCT04268589
- Testing
- virtual reality game
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Treatment Resistant Depression (TRD)
Ketamine Biomarker Validation
An EEG-based biomarker will be developed for the effects of ketamine infusion in patients with Depression. The effects of ketamine infusion on Depression symptoms and EEG signals will be analyzed.
- Trial name
- NCT07307768
- Testing
- Ketamine (0.25 mg/kg), Ketamine (0.5 mg/kg), Ketamine (0.75 mg/kg)
- Where
- United States
- Sponsor
- Soterix Medical
Major Depressive Disorder
Rapid Antidepressant Effects of Leucine
This randomized double-blind placebo-controlled crossover study seeks to evaluate the antidepressant effect of L-leucine, an essential amino acid, in patients with Major Depressive Disorder (MDD).
- Trial name
- NCT03079297
- Testing
- L-Leucine, Maltodextrin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Texas Southwestern Medical Center
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