Clinical trials: Depression Symptom
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Anxiety, Depression
Probiotics and the Microbiome: Clinical Intervention Trial for Anxiety and Depression
The proposed project will investigate the effects of probiotics on anxiety and associated psychological and physiological factors in humans.
- Trial name
- NCT02035878
- Testing
- Probiotics
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Acadia University
Caregiver Distress
Reducing Distress in Phase 1 Trial Caregivers: The P1-CaLL Study
This study seeks to decrease distress in the lives of the caregivers who are helping cancer patients who have entered a phase 1 clinical trial.
- Trial name
- NCT03557515
- Testing
- Stress Management and CBT, Stress Management and Metta-Meditation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Back Pain, Depressive Symptoms
Cannabidiol for Reduction of Brain Neuroinflammation
This study will investigate whether cannabidiol (CBD), the primary centrally and peripherally active non-intoxicating compound in the cannabis plant, exerts anti-neuroinflammatory effects in patients with chronic low back pain…
- Trial name
- CBD (NCT05066308)
- Testing
- CBD
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Depression, Advanced Cancer
Collaborative Care Intervention for Cancer Caregivers
The proposed randomized controlled trial will test the efficacy of a stepped collaborative care intervention, versus enhanced usual care arm, to reduce depression of cancer caregivers.
- Trial name
- NCT02944136
- Testing
- enhanced usual care, stepped collaborative care
- Where
- 2 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Depressive Disorder, Rheumatoid Arthritis
Clinical Study of Escitalopram Oxalate Combined With taVNS in Depression and Concomitant Inflammatory Symptoms
This study is expected to include 90 patients with major depressive disorder and rheumatoid arthritis as study subjects.Randomly divided into 3 groups: drug + VNS stimulation group, drug + sham stimulation group and drug group…
- Trial name
- NCT04037111
- Testing
- Transcutaneous electrical vagus nerve stimulation, drug treatment
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Depression
Behavioral Activation and Emotion-focused Interventions in the Treatment of Depression
The study is a single-case intervention study, evaluating effects of the treatment Behavioral activation and emotion-focused interventions for depression. Research question and hypothesis 1.
- Trial name
- NCT06023732
- Testing
- Behavioral activation and emotion-focused interventions
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Region Stockholm
Depression
Effects of Buprenorphine on Mood in Adults With a Range of Depressive Symptomatology
This study seeks to to study the effects of buprenorphine, a partial mu-opioid agonist, on depressed mood in a healthy young adults with a range of depressive symptomatology.
- Trial name
- BED (NCT02659787)
- Testing
- 0.2mg Buprenorphine
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Bipolar Disorder
Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode
The purpose of this study is to evaluate flexible doses (5-30mg) of aripiprazole versus placebo in patients with bipolar depression.
- Trial name
- NCT00080314
- Testing
- Aripiprazole
- Where
- 28 sites in United States
- Volunteers
- 400 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy Elderly
Effects of Exercise on Depression Symptoms, Physical Function, and Quality of Life in Community-Dwelling Elderly
The purpose of this study was to investigate the effects of 8-week exercise training on depression symptoms, physical functions, and quality of life in the community-dwelling elderly.
- Trial name
- NCT00931814
- Testing
- exercise training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Treatment Resistant Depression (TRD), Chronic Pain
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
The goal of this clinical trial is to understand the effect of ketamine on the brain in people with treatment-resistant depression (TRD).
- Trial name
- NCT07247006
- Testing
- Ketamine hydrochloride injection
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Bipolar Disorder, Depression
Disseminating Evidence-based Mood Disorder Chronic Care Models
This study will determine if a version of the chronic care model for individuals with mood disorders can improve patient health.
- Trial name
- NCT01615458
- Testing
- Chronic Care Model for Mood Disorders
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Major Depressive Disorder
Wellness Monitoring for Major Depressive Disorder
The Wellness Monitoring for Major Depressive Disorder (MDD) study is a prospective, longitudinal, observational study aimed at identifying biomarkers of relapse in MDD.
- Trial name
- CBN-Well (NCT02934334)
- Testing
- Observational
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Sidney Kennedy
Post Traumatic Stress Disorder, Smoking
Computerized Tailored Intervention for Behavioral Sequelae of PTSD in Veterans
This project assesses the usability and feasibility of a multi-behavioral computerized, tailored intervention (CTI) or expert system delivered via the Internet for veterans with Post-Traumatic Stress symptoms.
- Conditions
- Post Traumatic Stress Disorder, Smoking, Anxiety, Depression
- Trial name
- CTI-PTSD (NCT01510834)
- Testing
- Multibehavioral, Computerized Tailored Intervention STR2IVE
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Pacific Islands Health Care System
Stress, Psychological, Stress, Physiological
Family-centered Mental Health Promotion Intervention
Goal: The long-term goal of the proposed research program is to test the effectiveness of a preventative behavioral intervention and to scale it up for use with broader immigrant populations to reduce stress and mental health…
- Conditions
- Stress, Psychological, Stress, Physiological, Anxiety, Depression
- Trial name
- NCT04453709
- Testing
- Problem Management Plus for Immigrants at family settings, Talk program with Community Support Service Pamphlet (CSS)
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Depression, Elderly
Collaborative Care for Depressed Elderly in Korea
Late-life depression is associated with physical limitations, greater functional impairment, increased utilization and cost of health care, and suicide.
- Conditions
- Depression, Elderly, Korean, Collaborative Care
- Trial name
- NCT01626716
- Testing
- care management
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- National Clinical Research Coordination Center, Seoul, Korea
Depression - Major Depressive Disorder
Association of Beta Blocker Use with Depressive Outcomes
An Observational Study to Explore the Association Between β-Blocker Use and Depressive Outcomes
- Trial name
- NCT06743633
- Volunteers
- 1,136 people
- Sponsor
- Chitkara University
Depression in Remission
A Study of SDI-118 in Participants in Remission From Depression
This is a multi-center, double-blind, randomized, placebo-controlled study to determine the safety, tolerability, and pharmacodynamics of SDI-118 in a once daily (QD) dosing regimen on male and female study participants reporting…
- Trial name
- NCT05212116
- Testing
- SDI-118
- Where
- 3 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Syndesi Therapeutics
Depression, Mental Disorder
Digital Training for Non-Specialist Health Workers to Deliver a Brief Psychological Treatment for Depression
The purpose of this 3-arm randomized controlled trial is to compare two forms of digital training (i.e., low-intensity and high-intensity) with traditional face-to-face training of non-specialist health workers to deliver an…
- Conditions
- Depression, Mental Disorder, Psychological
- Trial name
- ESSENCE (NCT04157816)
- Testing
- Face-to-Face Training, Digital Training, Coaching Support
- Where
- India
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
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