Clinical trials: Depression Symptom
Anxiety Disorders, Depressive Symptoms
Collaborative Redesign of Implementation Strategies for the Brief Intervention for School Clinicians
Schools are the most common venue for youth mental health services, but school mental health (SMH) typically does not use evidence-based clinical interventions (CI), common elements of effective mental health, or effective…
- Conditions
- Anxiety Disorders, Depressive Symptoms, Mental Health Issue
- Trial name
- BRISC (NCT06968949)
- Testing
- Unadapted Brief Intervention for School Clinicians (BRISC; BR-O), Brief Intervention for School Clinicians (BRISC) with Implementation Strategies Adapted for School-Employed Practitioners (BR-A)
- Volunteers
- 60 people
- Sponsor
- University of Washington
Diabetes, Pre-diabetes
Northern Manhattan Study of Metabolism and Mind
Pre-diabetes, type 2 diabetes, and their related conditions, adiposity and insulin resistance, are more prevalent in minorities Northern Manhattan compared to the general population of the United States.
- Conditions
- Diabetes, Pre-diabetes, Cognition - Other, Depressive Symptoms
- Trial name
- NOMEM (NCT02470260)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stress, Psychological Stress
Examine the Effects of Mindfulness in Woman With a History of Child Adversity
The aim of this pilot Randomized Controlled Trial (RCT) is to test whether brief mindfulness-based practices will improve well-being and health in women (age 30-50) with a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMA (NCT05255380)
- Testing
- Mindfulness and compassion-based practices; approximately 5-10 minutes two times/day, Mindful awareness and reporting of current thoughts and feelings, 2 times/day
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Loneliness, Social Isolation
Effectiveness of a Mobile Application in Improving Employees' Social Well-being.
The goal of this cluster randomized controlled trial is to learn if using Frendie PRO mobile application at workplaces improves social well-being in employees.
- Conditions
- Loneliness, Social Isolation, Social Support, Depressive Symptoms
- Trial name
- NCT06495801
- Testing
- Frendie PRO mobile application
- Where
- Finland
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Depressive Symptoms Mild to Moderate in Severity, Anxiety
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
With progression of cancer, patients and their caregivers experience challenging emotional distress, which can make them feel depressed and very anxious. Patients with advanced cancer often do not have long to live.
- Conditions
- Depressive Symptoms Mild to Moderate in Severity, Anxiety, Quality of Life (QOL), Caregiver Burden
- Trial name
- Keta-Care (NCT06665568)
- Testing
- Intranasal ketamine hydrochloride
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Depressive Symptoms, Hope
The Mindfulness-Based Psycho-Educational Program Focused on Emotion Regulation Strategies
In this study, the effects of a mindfulness-based emotion-focused psychoeducation program applied to individuals diagnosed with schizophrenia on emotion regulation difficulties, depressive symptoms, and hope levels will be…
- Conditions
- Depressive Symptoms, Hope, Difficulties of Emotion Regulation
- Trial name
- NCT06926049
- Testing
- The Effect of The Mindfulness-Based Psycho-Educational Program Focused on Emotions
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Gazi University
Depressive Symptoms, Anxiety
Living Well: A Digital ACT Intervention
Depression and anxiety are frequently comorbid and share mechanisms contributing to dysfunction. Transdiagnostic approaches, such as Acceptance and Commitment Therapy, streamline intervention and allow a broader population to…
- Conditions
- Depressive Symptoms, Anxiety, Emotional Disorders
- Trial name
- NCT04787809
- Testing
- Living Well
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Texas at Tyler
Self-reported Symptoms of Depression
Behavioral Study to Predict the Efficacy of a Self-Help Tool
The study aims to examine whether the investigators can predict, on the level of individual participants who have symptoms of depression, who will benefit more from self-help tools based on principles of behavioral activation vs.
- Trial name
- NCT06631183
- Testing
- Self-help information based on principles of behavioral activation, Self-help information based on principles of cognitive restructuring
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Trustees of Princeton University
Early Life Adversity, Microbiome, Human
Between the Belly and the Brain: Distorted Gut-brain Crosstalk in Early-life Adversity
The goal of this observational study is to learn about the effects of early-life adversity (ELA) on the composition of children's microbiome and on their psychosocial functioning.
- Conditions
- Early Life Adversity, Microbiome, Human, Anxiety Symptoms, Depressive Symptoms
- Trial name
- BellyBrain (NCT06922773)
- Testing
- Completion of questionnaires; child psychiatric screening; faecal sample analysis
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Dementia Caregiver, Depressive Symptoms
Telephone-coached "Graphic Narrative" Bibliotherapy for Dementia Caregivers
This study aims to assess the efficacy of telephone-coached graphic narrative bibliotherapy in improving dementia caregiver depressive symptoms compared with the booklet group.
- Conditions
- Dementia Caregiver, Depressive Symptoms, Caregiving Appraisal
- Trial name
- NCT06413849
- Testing
- Telephone coached graphic narrative bibliotherapy, Control group
- Where
- Hong Kong
- Volunteers
- 128 people
- Sponsor
- The Hong Kong Polytechnic University
Infertility, Female, Distress, Emotional
Mindful Self-Compassion (MSC) for Infertility Related Distress
This study will test a psychological intervention for the treatment of distress related to infertility. The intervention will pair reading a book "The Mindful Self-Compassion Workbook" by Kristin Neff with guided meditations…
- Conditions
- Infertility, Female, Distress, Emotional, Depressive Symptoms, Anxiety
- Trial name
- NCT05183568
- Testing
- Mindful Self-Compassion
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Regina
Depressive Symptoms, Anxiety Symptoms
The Role of Music Therapy in Improving College Students' Mental Health and Self-efficacy
Interventional Trial (Randomized Experimental Design) Study Goal: This clinical trial aims to evaluate the effectiveness of a structured music therapy program in improving mental health (depression, anxiety, stress) and…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Stress Symptoms
- Trial name
- NCT06917170
- Testing
- Structured Music Therapy Program
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hubei University of Science and Technology
Alcohol Drinking, Social Acceptance
PLANTS Pilot Trial
This pilot cluster-randomized controlled trial will evaluate the PLANTS (Providing LGBTQ+ Adolescents with Nurturance, Trustworthiness, and Safety) course among high school staff.
- Conditions
- Alcohol Drinking, Social Acceptance, Depressive Symptoms, Bullying
- Trial name
- PLANTS (NCT05897827)
- Testing
- PLANTS, EMAILS
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anxiety Symptoms, Depressive Symptoms
Strengthening Health and Insight in New Educators
Teachers are at notable risk for depression and anxiety. The present study tests an app-based mindfulness intervention for teachers in their final year of training with the goal of preventing the deterioration of their mental…
- Trial name
- SHINE (NCT06745934)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Depression, Depressive Symptoms
Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psychosocial Needs of Individuals Living With Cancer
The purpose of this research study is to evaluate a mobile application (app) for depression treatment called "Moodivate" among cancer survivors.
- Conditions
- Depression, Depressive Symptoms, Cancer
- Trial name
- NCT05932810
- Testing
- Behavioral Activation Therapy app, Treatment as Usual
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Depressive Symptoms, Anxiety
Mental Health Mobile Apps for Adults
In Hong Kong, the shortage of mental health professionals has been a public health concern for many decades. The World Health Organization (WHO) recommends self-care intervention as one of the most promising and exciting new…
- Conditions
- Depressive Symptoms, Anxiety, Well-Being, Psychological
- Trial name
- NCT06099301
- Testing
- Brief advice of a list of mobile apps
- Where
- Hong Kong
- Volunteers
- 234 people
- Sponsor
- Hong Kong Metropolitan University
Cardiovascular Diseases, Coronary Artery Disease
Depressive Symptoms After Cardiac Surgery
The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Depression
- Trial name
- PCD (NCT06706323)
- Where
- 2 sites in Switzerland
- Volunteers
- 300 people
- Sponsor
- Roland von Känel
Physical Activity Levels, Cardiovascular Fitness
Effects of Virtual Reality Exercise on Promoting Physical Activity and Health Among College Students
The purpose of this research is to examine the effectiveness of a 4-week immersive-virtual reality (VR) exercise bike intervention on college students' physiological outcomes (physical activity levels, cardiovascular fitness, and…
- Conditions
- Physical Activity Levels, Cardiovascular Fitness, Body Composition, Situational Motivation
- Trial name
- NCT06902727
- Testing
- VR-based exercise bike, Usual routine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Depressive Symptoms, Chronic Insomnia
Tai Chi Versus Conventional Exercise to Alleviate Depression in Insomniacs
This study aims to examine the effectiveness of Tai Chi and conventional exercise in alleviating depressive symptoms in older insomniacs.
- Trial name
- NCT05482646
- Testing
- Tai Chi, Conventional exercise, Health Education Control
- Where
- Hong Kong
- Volunteers
- 420 people
- Sponsor
- The University of Hong Kong