Clinical trials: Depression Symptom
Acute Coronary Syndromes, Depression
Integrating Depression Care in Acute Coronary Syndromes Care in China
The overall goal of this study is to develop, pilot test, implement, and evaluate a nurse-coordinated depression care model integrated into the care of Acute Coronary Syndromes (ACS) patients with rigorous assessment of…
- Trial name
- I-Care (NCT02195193)
- Testing
- Integrated care
- Where
- China
- Volunteers
- 4,043 people
- Sponsor
- The George Institute for Global Health, China
Postpartum Care, First Birth
Meleis's Transition Theory on Postpartum Difficulties and Quality of Life in Primipara Mothers
The randomized controlled experimental study sought to determine the impact of the training structured according to Meleis's Transition Theory on postpartum difficulties and quality of life in primipara mothers.
- Conditions
- Postpartum Care, First Birth, Cesarean Section
- Trial name
- NCT05533021
- Testing
- Training and Consultancy
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Depression, Hiv
Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV
Depression in HIV occurs commonly and causes poor HIV outcomes with public health implications. Depression prevalence in HIV-infected persons is estimated at 26% compared to 5% in the general population.
- Trial name
- NCT07007221
- Testing
- Metformin, Fluoxetine, Metformin+Fluoxetine
- Sponsor
- University of Minnesota
Suicide, Suicide Threat
Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department
Current treatment for acutely suicidal patients are limited to hospitalization, psychotherapy, electro-convulsant therapy, or a combination of the aforementioned. However, this has added to the national boarding problem.
- Conditions
- Suicide, Suicide Threat, Depression Severe
- Trial name
- NCT04260607
- Testing
- Ketamine Hydrochloride, Normal saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Naval Medical Center Camp Lejeune
Depressive Symptoms, Anxiety Symptoms
Effects of Inserting Exercises During Physical Education Classes on Anxiety and Depression Symptoms in Adolescents
The main objective of this project will be to verify if the insertion of diaphragmatic, cardiorespiratory and strength breathing exercises and cooperative sports activities in Physical Education classes, during a period of 12…
- Trial name
- NCT05561192
- Testing
- Diaphragmatic breathing exercises, Cardiorespiratory and strength exercise, Cooperative sports activities group
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Depressive Disorder, Major
Transcranial Low Intensity Focused Ultrasound Neuromodulation as a Probe to Study Human Emotion and Cognitive Function
The purpose of this study is to assess the low-intensity focused ultrasound pulsation (LIFUP) neuromodulation on emotion processing in healthy individuals, and to assess the overall safety of the LIFUP to stimulate or inhibit…
- Trial name
- NCT05194332
- Testing
- LIFUP sonication to the amygdala
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Depression, Asthma
Antidepressant Treatment at an Inner City Asthma Clinic
Asthma is common with an increasing prevalence and mortality especially in low-income and minority populations. The course of asthma appears to be influenced by mood and emotions.
- Trial name
- NCT01324700
- Testing
- High severity group: Escitalopram, Low severity group: Escitalopram
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University of Texas Southwestern Medical Center
Weight Gain
Exenatide for the Treatment of Weight Gain Associated With Olanzapine in Obese Adults
The purpose of this research study is to test the safety and efficacy (how well it works) of exenatide as a treatment for weight gain associated with olanzapine in obese adults with Bipolar Disorder, Major Depressive Disorder…
- Trial name
- NCT00845507
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Cincinnati
Functional Dyspepsia, Depression
Zuojin Wan Combined With Rabeprazole or Mosapride for the Treatment of Functional Dyspepsia Combined With Depression
To evaluate the symptom improvement of Zuojinwan combined with rabeprazole or Zuojinwan combined with a mosapride regimen in patients with functional dyspepsia combined with depression (liver-stomach depression-heat type) using…
- Trial name
- NCT06481371
- Testing
- zuojinwan, Rabeprazole sodium enteric-coated tablets, mosapride citrate
- Volunteers
- 120 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Kava, Anxiety
Effect of Kava on Anxiety and Stress in Cancer Survivors
This is a pilot, two-arm, randomized, blinded, placebo-controlled cross-over clinical trial to study the safety and effect of 14 days of kava on anxiety and physiologic stress in survivors of cancer and its treatment.
- Conditions
- Kava, Anxiety, Stress, Cancer
- Trial name
- NCT06213298
- Testing
- Kava
- Where
- United States
- Sponsor
- Masonic Cancer Center, University of Minnesota
Depression
Social Connectedness Group Intervention in Depression
This study evaluates the feasibility of the Groups for Health (G4H) intervention for adults accessing support for depression in the UK.
- Trial name
- G4H-A (NCT03446963)
- Testing
- Groups for Health
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- University of Nottingham
Depression, Autoimmune Diseases
The Pathogenesis of Depression - Possible Autoimmune Mechanisms
It has long been claimed that depression, and other psychiatric illness, might be a manifestation of immune dysregulation involving the Central nervous system.
- Trial name
- NCT05293899
- Testing
- exome sequencing approach
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- HaEmek Medical Center, Israel
Osteoarthritis, Knee, Osteoarthritis, Hip
Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity
Chronic conditions such as knee or hip osteoarthritis (OA), chronic obstructive pulmonary disease (COPD), heart failure (HF), coronary heart disease (CHD), hypertension, type 2 diabetes mellitus (T2DM) and depression are among…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Heart Failure, Coronary Heart Disease
- Trial name
- MOBILIZE (NCT04645732)
- Testing
- Personalized exercise therapy and self-management support program, Usual care
- Where
- 16 sites in Denmark
- Volunteers
- 228 people
- Sponsor
- University of Southern Denmark
Bipolar Disorder, Anxiety Disorders
Double-Blind Placebo-Controlled Trial of Riluzole in Pediatric Bipolar Disorder
Pediatric Bipolar Disorder (BD) is uncommon in children. Its symptoms include periods of manic behavior (being overly happy or giddy, feeling grandiose, feeling a decreased need for sleep, having too much energy, moving more than…
- Conditions
- Bipolar Disorder, Anxiety Disorders, Bipolar Affective Disorder, Bipolar Depression
- Trial name
- NCT00805493
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Anxiety
Information Sources and Their Relationship to Depressive and Anxiety Symptoms During the COVID-19 Pandemic: A Network Study
This study aims to investigate the association between the use different information sources to obtain information about the COVID-19 pandemic and symptoms of psychopathology (i.e., depression and anxiety).
- Trial name
- NCT04444336
- Testing
- Cross-sectional study examining the impact of information sources to obtain information about COVID-19 on depression and anxiety symptoms
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Opioid-use Disorder, Addiction
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
- Trial name
- CLARO (NCT04559893)
- Testing
- Collaborative Care
- Where
- 16 sites in United States
- Volunteers
- 729 people
- Sponsor
- RAND
Anxiety, Depression
Virtual Intervention for Behavioral Health in Emerging Adults; "VIBE in the Parks"
The goal of this study is first to develop and adapt a digital low-intensity treatment, "VIBE in the Parks", for adolescents and young adults (AYA) who visit programming at the Chicago Park District.
- Trial name
- VIBE (NCT07539636)
- Testing
- "VIBE in the Parks", Digital Control
- Volunteers
- 268 people
- Sponsor
- University of Illinois Chicago
Depression
Prevention of Depression in Spouses of People With Cognitive Impairment
This study evaluates the effectiveness of a problem-solving training program in preventing depression in the spouses or family caregivers of persons with mild cognitive impairment or early dementia.
- Trial name
- NCT00321971
- Testing
- PST-MCI/AD Caregiving, NT-MCI/AD Caregiving
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Coronary Artery Disease, Congestive Heart Failure
A Collaborative Care Program to Improve Depression Treatment in Cardiac Patients
Depression in cardiac patients is common, persistent, and deadly. However, the vast majority of cardiac patients with depression go unrecognized and untreated, despite the existence of treatments that clearly improve depressive…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Arrhythmia, Depression
- Trial name
- NCT00847132
- Testing
- Collaborative Care Treatment, Usual Care Treatment
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Massachusetts General Hospital
Sarcoidosis, Fatigue
Virtual Patient Groups for Sarcoidosis Associated Fatigue
This research study is testing whether Mindfulness-Based Stress Reduction (MBSR) can help reduce fatigue in people with sarcoidosis. The study will also look at whether MBSR can improve symptoms of anxiety and depression.
- Conditions
- Sarcoidosis, Fatigue, Depression, Anxiety
- Trial name
- SupportSarc (NCT07073963)
- Testing
- Virtual Mindfulness Based Stress Reduction Group, Virtual sarcoidosis support group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
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