Clinical trials: Depression Symptom
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Depressive Symptoms
TreadWill, an Automated Intervention for Depressive Symptoms
TreadWill is a fully automated digital intervention that provides a multi-modal treatment for depressive symptoms. It includes: 1. Slides and interactive text-based conversations based on Cognitive Behavioral Therapy (CBT); 2.
- Trial name
- NCT04703491
- Testing
- Interactive and full-featured intervention, Feature-limited CCBT, Waitlist control
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Indian Institute of Technology Kanpur
Chronic Subdural Hematoma, Epilepsy; Seizure
Generating Evidence on NonEpileptic, Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hematomas
Some patients with chronic subdural hematomas and transient neurological symptoms do not respond to standard antiepileptic drugs.
- Conditions
- Chronic Subdural Hematoma, Epilepsy; Seizure, Cortical Depression; Cortical Depolarization, Nonepileptic, Stereotypical and Intermittent Symptoms
- Trial name
- GENESIS (NCT04759196)
- Testing
- Topamax, Levetiracetam
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Université de Sherbrooke
Hypertension, Diabetes Mellitus
Hypertension and Diabetes Assessment in the Rohingya Refugee Population and in the Host Communities in Bangladesh
Due to a massive outbreak of violence against the Rohingya minority residing in the Rakhine State of Myanmar in late 2017, several hundred thousand Rohingya fled the country and sought a shelter in Bangladesh.
- Conditions
- Hypertension, Diabetes Mellitus, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT04307875
- Testing
- Blood pressure measurement (sphygmomanometer), Blood glucose measurement, psychometric tests
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Ptsd, Depressive Symptoms
Transcendental Meditation and PTSD
This paper describes the rationale and design of a Phase 3 RCT comparing Transcendental Meditation to Present Centered Therapy for posttraumatic stress disorder (PTSD), suicidal ideation, alcohol use, and depressive symptoms in…
- Conditions
- Ptsd, Depressive Symptoms, Suicidal Ideation, Alcohol Use, Unspecified
- Trial name
- NCT04856033
- Testing
- TM, PCT
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- David Lynch Foundation
Depressive Disorder, Major, Depressive Symptoms
ICBT for Depression - A Factorial Investigation of Kinds of Therapist Support and Self-/Expert-selected Content
The study is a factorial randomized controlled trial investigating the efficacy of difference versions of internet-administered cognitive behavioral therapy.
- Trial name
- NCT04260750
- Testing
- Internet-administered Cognitive behavioral therapy (ICBT)
- Where
- Sweden
- Volunteers
- 246 people
- Sponsor
- Linkoeping University
Depressive Symptoms, Anxious Symptoms
Mindfulness for Emerging Adults Experiencing Anxious and/or Depressive Symptoms
Emerging adults (EA; 18 to 29 years old) in Canada are among the age group with highest risk of developing mental health issues. Despite this, they experience especially long wait-times for mental health services.
- Trial name
- NCT03769233
- Testing
- Mindfulness-based Intervention
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- York University
Depressive Symptoms, Coping Skills
Effects of Interpersonal Relational Role Analysis
Introduction: Interpersonal Relational Role Analysis (IRRA) is a psychosocial group intervention that allows individuals to see the problems they experience in interpersonal relationships and interactions in the group environment…
- Trial name
- NCT04832451
- Testing
- Interpersonal Relational Role Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Ankara University
Depression, Depressive Symptoms
Meru Health Ascend Mobile Intervention for Depression in Middle Aged and Older Adults
Using technology to deliver depression interventions is one way could alleviate the public health burden of depression. The study is testing a mobile app intervention program for depression that uses cognitive behavioral skills…
- Trial name
- NCT03652948
- Testing
- Meru Health Ascend Program
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Palo Alto Veterans Institute for Research
Depression, Adolescent Behavior
Volunteering as an Intervention to Reduce Depression Among Adolescents
The purpose of the present study is to test in a preliminary manner an innovative strategy for treating depression among adolescents (alongside existing therapy) using community volunteerism.
- Conditions
- Depression, Adolescent Behavior, Depressive Symptoms
- Trial name
- NCT03816215
- Testing
- Volunteer experience
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Wake Forest University Health Sciences
Burnout Syndrome, Psychological Distress
Web-based ACT to Support Parents With Children With Chronic and Developmental Conditions
Parents of children with a chronic disease or functional disabilities have an increased risk of stress-related distress and reduced quality of life.
- Conditions
- Burnout Syndrome, Psychological Distress, Depressive Symptoms, Quality of Life
- Trial name
- Uupu (NCT04250012)
- Testing
- Internet-based ACT intervention, Psychoeducation
- Where
- Finland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Stress, Quality of Life
The Delivery of "Doing What Matters in Times of Stress: An Illustrated Guide"
The feasibility study for the delivery of the "Doing What Matters in Times of Stress: An Illustrated Guide" will be carried out for Turkish and Syrian individuals with psychological stress.
- Conditions
- Stress, Quality of Life, Depressive Symptoms
- Trial name
- NCT04631887
- Testing
- Doing What Matters in Times of Stress: An Illustrated Guide
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Koç University
Depression, Depressive Symptoms
Antidepressant Decision Aid for Major Depressive Disorder Patients
The purpose of this study is to determine whether Antidepressant Decision Aid for Major Depressive Disorder is feasible and effective in involving patients in the decision-making process when initiating pharmacotherapy.
- Conditions
- Depression, Depressive Symptoms, Depressive Disorder, Major, Mood Disorders
- Trial name
- ADAM (NCT04761757)
- Testing
- Booklet of Scripts of Doctors, Booklet of Scripts for Doctors and the Antidepressant Decision Aid for Major depressive disorder patients (ADAM)
- Where
- 17 sites in Malaysia
- Volunteers
- 752 people
- Sponsor
- University of Malaya
Cognitive Symptom, Depression
Psychotropic Drug Use in the Elderly Living in Nursing Homes and the Influence of a Structured Drug Review
The overall aim of this study is to explore if a structured drug review will change clinical symptoms and the psychotropic drugs prescription rate in the elderly living in nursing homes (participants of the study).
- Conditions
- Cognitive Symptom, Depression, Anxiety, Neuropsychiatric Syndrome
- Trial name
- NCT03736577
- Testing
- Drug reviews with NorGeP-NH
- Where
- Norway
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Depressive Symptoms, Anxiety
Probiotics, Brain Structure and Psychological Variables
Theory and research on the gut-brain-axis emphasize complex interactions between the gut microbiota, immunological and hormonal responses, brain function, brain structure, as well as resulting behavioral manifestations, such as…
- Conditions
- Depressive Symptoms, Anxiety, Stress
- Trial name
- ProBrain01 (NCT03478527)
- Testing
- Vivomixx® powder
- Where
- Germany
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depressive Symptoms, Loneliness
Online Mindfulness-Based College for Young Adults
MB-College (MBC) is an 9-week, 9 session program (i.e., the study intervention being tested in the RCT) providing systematic and intensive training in mindfulness meditation practices, applied to health behaviors relevant to…
- Conditions
- Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness
- Trial name
- MBC (NCT04733300)
- Testing
- Mindfulness-Based College for Young Adults, Health Education for Young Adults
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Eric Loucks
Caregivers, Dementia
Powerful Tools for Caregivers of Dementia Patients
The purpose of this study is to examine if a psycho-educational intervention for caregivers of patients with dementia will decrease caregiver burden, increase caregiver physical activity, and decrease the reporting of behavioral…
- Conditions
- Caregivers, Dementia, Alzheimer Disease
- Trial name
- PTC-dementia (NCT02697721)
- Testing
- Powerful Tools for Caregivers, Control with delayed intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
COPD, Anxiety State
Assessment of Stress Levels and Depressive and Anxiety Symptoms in Patients With COPD
The aim of the study was to assess the levels of depression, anxiety and stress in patients with COPD qualified for In-hospital pulmonary rehabilitation program
- Conditions
- COPD, Anxiety State, Stress, Depressive Symptoms
- Trial name
- NCT04726917
- Testing
- Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 51 people
- Sponsor
- The Opole University of Technology
Immunodeficiency Virus, Human, Depressive Symptoms
Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa
The purpose of this study is to conduct a two-arm effectiveness trial in Cape Town, South Africa of a Xhosa-adapted, nurse-delivered, cognitive behavioral therapy (CBT) treatment for depression and adherence, integrated into the…
- Trial name
- NCT02696824
- Testing
- Cognitive Behavioral Therapy for Adherence and Depression
- Where
- 3 sites in United States, South Africa
- Volunteers
- 161 people
- Sponsor
- University of Miami
Post-Concussion Syndrome, Anxiety Disorders and Symptoms
Breath Control and Mindfulness for Post Concussion Anxiety and Depression: a Feasibility Study
Persistent-post-concussion symptoms (PPCS) is a condition that effects on average one in seven persons following a concussion. Anxiety and depression symptoms are experienced by over one-third of those with PPCS.
- Conditions
- Post-Concussion Syndrome, Anxiety Disorders and Symptoms, Depressive Symptoms
- Trial name
- NCT04708522
- Testing
- Breath Control - Equal Breathing Technique, Guided Mindfulness Exercise, Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University, Canada