Clinical trials: Depression Symptom
Major Depressive Disorder
Cognitive Training for Depression II
This study is evaluating the effects of two brain training exercises on: memory, cognitive processing and depression symptoms.
- Trial name
- NCT01934491
- Testing
- Cognitive Training A, Cognitive Training B
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Osteoarthritis (OA) of the Knee
Investigation of Biopsychosocial Characteristics of Individuals with Knee Osteoarthritis
Since pain and depression are observed together in rheumatic diseases, the concept of limitation caused by the disease and health-related quality of life becomes more determinant than radiological joint damage.
- Trial name
- NCT06591715
- Testing
- Home exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Aysima Barlak
Depression
Sleep Deprivation Plus Paroxetine for Treating Major Depression in Elderly Individuals
This study will determine the effectiveness of total sleep deprivation (TSD) for one night plus paroxetine versus either TSD plus placebo or paroxetine alone in inducing rapid symptom resolution of major depression in the elderly.
- Trial name
- NCT00178035
- Testing
- paroxetine, One night of Total Sleep Deprivation
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Pittsburgh
Major Depressive Episode
Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders
Despite international efforts to identify biomarkers of depression, none has been transferred to clinical practice, neither for diagnosis, evolution, nor therapeutic response.
- Trial name
- SoPsy-SoSad (NCT05866991)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Sleep
The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression
The aim of this trial is to investigate the effects of a single bout of aerobic exercise on sleep in patients with depression.
- Conditions
- Depression, Sleep, Sleep Disorder, Sleep Disturbance
- Trial name
- EASED (NCT03673397)
- Testing
- Aerobic exercise, bicycle ergometer
- Where
- Switzerland
- Volunteers
- 92 people
- Sponsor
- Oberwaid AG
Depression, Anxiety
Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services
The primary aim of this study is to determine the feasibility and acceptability of the W-GenZD mobile application among a group of adolescents and who have screened and triaged into low-intensity treatment within the Children's…
- Trial name
- NCT05372913
- Testing
- Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Woebot Health
Depression, Anxiety
Mood Lifters for Undergraduates
Large-scale, effective, low-cost, and evidence-based programs that can nimbly translate new research discoveries into prevention and care for psychosocial-based problems are urgently needed since the vast majority of people who…
- Conditions
- Depression, Anxiety, Mood Disorders, Mental Health Wellness 1
- Trial name
- ML-UP (NCT05684120)
- Testing
- Mood Lifters for Undergraduates
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Delirium, Respiratory Depression
Acupuncture for Sedation in the Intensive Care Unit (ICU)
BACKGROUND Many patients in the trauma intensive care unit (TICU) require mechanical ventilation and sedation or anxiolysis. Mechanical ventilation means that a machine is helping a patient breathe if he can't breathe on his own.
- Conditions
- Delirium, Respiratory Depression, Overmedication
- Trial name
- NCT01362270
- Testing
- Verum Acupuncture
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Oregon Health and Science University
Oral Lichen Planus, Thyroid Disease
Association Between Oral Lichen Planus and Thyroid Disease
The goal of this observational study is to determine the prevalence of thyroid disease in adults with oral lichen planus (OLP) treated at the Dental Hospital of the University of Barcelona (HOUB), and to evaluate the association…
- Trial name
- NCT06550154
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Subthreshold Depression
Needle-embedding Therapy Alleviates Depressive Symptoms and Resets the Function of Executive Control System in Subthreshold Depression People
The main objective of this trial is to evaluate the effectiveness of treating subthreshold depression by needle-embedding therapy.
- Trial name
- NCT04319562
- Testing
- needle-embedding therapy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Depression, Continuous Antidepressant Abuse
Development of Escitalopram Genomic Device by Using Candidate Gene Approach and Genome-Wide Scanning
To reveal the genetic determinants of the treatment outcome of escitalopram in depressed patients (by using candidate gene approach and whole genome scanning).
- Conditions
- Depression, Continuous Antidepressant Abuse, Adverse Reaction to Drug
- Trial name
- NCT00935246
- Testing
- Escitalopram
- Where
- South Korea
- Volunteers
- 202 people
- Sponsor
- Samsung Medical Center
Depression
A Randomized Clinical Trial for Depressed Mothers at Primary Care Level
A randomized clinical trial was carried out at primary care level in Santiago, Chile to compare a pharmacological intervention for depressed mothers controlled by phone from a central level (TM) and the usual treatment (TH) and…
- Trial name
- DMH (NCT00519051)
- Testing
- monitorized pharmacotherapy with antidepressants drugs (Fluoxetine)
- Where
- Chile
- Volunteers
- 345 people
- Sponsor
- Fondo Nacional de Desarrollo Científico y Tecnológico, Chile
Wheel-chair Dependent Elders
Improvement and Mechanism of Wheel-chair Music Aerobic Exercise on Depression and Insomnia Among the Elderly in Long-term Care Facilities
Investigators anticipate to develop a customized WC-MAE for the improvement of insomnia and depression in wheel-chair dependent elders, and to identify related mechanisms as biomarkers for prediction and prevention of insomnia…
- Trial name
- NCT02256020
- Testing
- Original lifestyle, Wheel-chair music aerobic exercise (WC-MAE)
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Hepatitis C, Depression
Hepatitis C Translating Initiatives for Depression Into Effective Solutions
Chronic infection with hepatitis C (CHC) is a common and expensive condition, and it disproportionately affects Veterans. Treatment with antiviral therapy reduces liver disease progression and improves health related quality of…
- Trial name
- HEPTIDES (NCT01143896)
- Testing
- Depression collaborative care model
- Where
- 4 sites in United States
- Volunteers
- 309 people
- Sponsor
- VA Office of Research and Development
Neuropathic Pain, Anxiety Disorder/Anxiety State
Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer
Head and neck cancers are a source of complications and after-effects related to the disease and treatment. These cancers and their treatment alter the quality of life of patients and generate pain with physical and psychological…
- Conditions
- Neuropathic Pain, Anxiety Disorder/Anxiety State, Pain, Chronic, Alcohol Use Disorder
- Trial name
- DIP-CAOS (NCT05505188)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Post-stroke Depression
Transcranial Direct Current Stimulation on Post Stroke Depression
The aim of the research is to address the critical gap that limited number of RCTs are conducted on this topic. To further explore the efficacy of tDCs, large sample sizes, large follow up period and rigorously controlled…
- Trial name
- NCT06598670
- Testing
- tDCS, Conventional treatment
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Resistant Depression, Treatment, Bipolar Depression
Efficacy and Biomarkers of Response of TBS in Treatment Resistant Depression
Theta Burst Transcranial Magnetic Stimulation (TBS) in dorsolateral prefrontal cortex (DLPFC) has shown efficacy and safety as an adjuvant strategy for resistant to treatment depression (RTD) in daily sessions during 4-6 weeks…
- Trial name
- EMTtfNI (NCT04998773)
- Testing
- Theta Burst Transcranial Magnetic Bilateral Stimulation, Theta Burst Transcranial Magnetic Unilateral Stimulation
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Stroke
Psychosocial/Behavioral Intervention in Post-Stroke Depression
The primary aim of this study is to determine the effect of a nurse-delivered psychosocial/behavioral intervention on reduction of depression in community dwelling post-stroke patients.
- Trial name
- NCT00194454
- Testing
- Modified cognitive behavioral therapy plus problem-solving, usual care
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Washington
Cognition, Depression
To Enhance Cognition in Late Life Depression Using Transcranial Direct Current Stimulation
Late Life Depression (LLD) is a serious health problem which not only causes depressed mood but also results in impairments in memory and attention.
- Trial name
- NCT02212366
- Testing
- Active TDCS
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Centre for Addiction and Mental Health
Premenstrual Syndrome, Anxiety
The Efficacy of Lavender Herbal Tea in Premenstrual Syndrome
Premenstrual syndrome (PMS) is a common but complex condition defined as a combination of emotional, psychological, and physical symptoms that occur during the luteal phase of the menstrual cycle, usually between 2 and 14 days…
- Conditions
- Premenstrual Syndrome, Anxiety, Depression, Stress
- Trial name
- NCT07737366
- Testing
- Lavender herbal tea
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
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