Clinical trials: Depression Symptom
Anxiety, Depression
An Open Trial of Metacognitive Therapy for Anxiety and Depression in Cancer
Survival rates in cancer continue to improve, with over 2 million adult cancer survivors in the United Kingdom, projected to increase to 4 million by 2030.
- Conditions
- Anxiety, Depression, Cancer
- Trial name
- NCT02580656
- Testing
- Metacognitive Therapy
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Liverpool
Depressive Symptoms
Investigating the Effect of a Smartphone-based Serious Game on Depressive Symptoms.
The objective of the present project is to study the effect of a smartphone-based serious game intervention for depressive symptoms.
- Trial name
- NCT04988529
- Testing
- Smartphone-based serious game intervention
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universitat Jaume I
Chronic Back Pain, Depression
MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression
The proposed study seeks to evaluate effectiveness, implementation processes, and cost of MOTIVATE among older Veterans with chronic musculoskeletal (MSK) pain and comorbid depressive symptoms.
- Conditions
- Chronic Back Pain, Depression, Aging, Musculoskeletal Pain
- Trial name
- MOTIVATE_IIR (NCT05220202)
- Testing
- Behavioral Intervention Group (MOTIVATE)
- Where
- 2 sites in United States
- Volunteers
- 214 people
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
Digital Single Session Intervention for Youth Mental Health
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist…
- Conditions
- Anxiety, Depression, Conduct Disorder, Stress
- Trial name
- NCT05449002
- Testing
- Practicing the Opposite (PTO), Usual Clinical Care
- Where
- 5 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Harvard University
Depressive Symptoms, Anxiety
Asynchronous Techniques for the Delivery of Empirically Supported Psychotherapies
The aim of this study is to test the feasibility, acceptability and efficacy of methods for delivering mental health support when real-time communication is not possible (e.g.
- Conditions
- Depressive Symptoms, Anxiety, Stress, Impairment
- Trial name
- NCT05122429
- Testing
- e-Health Treatment
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Colorectal Cancer, Depression
Studying Pain and Symptom Distress in Patients With Advanced Colon Cancer, Rectal Cancer, Pancreatic Cancer, or Liver Cancer
RATIONALE: Studying a patient's understanding of his or her illness, pain, symptoms, and quality-of-life may help the study of advanced cancer and may help patients live more comfortably.
- Conditions
- Colorectal Cancer, Depression, Fatigue, Liver Cancer
- Trial name
- NCT00950144
- Testing
- medical chart review, questionnaire administration, study of socioeconomic and demographic variables
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- City of Hope Medical Center
Depression
To Demonstrate the Relative Bioavailability of Geneva and Basel (Anafranil) 25 mg Clomipramine Hydrochloride Capsules Under Fed and Fasted Conditions
To demonstrate the relative bioavailability of Geneva and Basel (Anafranil) 25 mg Clomipramine Hydrochloride capsules under fed and fasted conditions.
- Trial name
- NCT00913952
- Testing
- Geneva 25 mg Clomipramine Hydrochloride Capsules Under Fasting Conditions, Geneva 25 mg Clomipramine Hydrochloride Capsules Under Fed Conditions, Basel (Anafranil) 25 mg Clomipramine Hydrochloride Capsules Under Fed Conditions
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sandoz
Depression, Anxiety
Mental Health First Aid for College Students
Most college students with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Eating Disorders
- Trial name
- NCT02021344
- Testing
- Mental Health First Aid
- Where
- United States
- Volunteers
- 2,543 people
- Sponsor
- University of Michigan
Depression, Bipolar Disorder
Prevention of Mood Disorders by Folic Acid Supplementation
The purpose of this study is to determine whether daily folic acid supplements can prevent new episodes of mood disorder in young people (aged 14-24 years) of biological parents with current or past history of depression or…
- Trial name
- PRE-EMPT (NCT00459264)
- Testing
- Folic Acid
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Chronic Hepatitis C
Efficacy of Paroxetine in the Prevention of Depressive Syndrome in Patients With Chronic Hepatitis C Treated by PEG-Interferon Alfa Plus Ribavirin
Depression is a common side effect of interferon in the treatment of chronic hepatitis C. The aim of this study is to assess the efficacy and safety of paroxetine, an antidepressant agent, in the prevention of depression induced…
- Trial name
- NCT00196664
- Testing
- Paroxetine
- Where
- France
- Volunteers
- 144 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Pregnancy, Postpartum Period
Effect of Exercise on Perinatal Depression
Fifteen percent of women experience depression during pregnancy or postpartum (i.e., perinatal depression). Furthermore, 38% of low income women experience postpartum depression.
- Conditions
- Pregnancy, Postpartum Period, Depression
- Trial name
- NCT02791932
- Testing
- Exercise
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depressive Disorder
Safety and Efficacy Study in Patients With Major Depressive Disorder
The purpose of this study is to test if GSK163090 can reduce the symptoms of depression. The safety and how well the body can handle the drug will also be investigated.
- Trial name
- NCT00896363
- Testing
- GSK163090 1 mg, GSK163090 3 mg
- Where
- 15 sites in Russia
- Volunteers
- 99 people
- Sponsor
- GlaxoSmithKline
Pain, Neuropathic Pain
Assessments on Current Pain Managements in Upper Gastrointestinal Cancer Patients
Pain is one of the most common symptoms associated with cancer. The approach to pain management compresses routine pain assessments, utilizes both pharmacologic and nonpharmacologic interventions, and requires ongoing…
- Conditions
- Pain, Neuropathic Pain, Depression, Quality of Life
- Trial name
- NCT01718821
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Cheng Kung University
Stress, Anxiety
A Brief Online Mindfulness Intervention: An RCT Protocol
University students often experience emotional distress that originates from inside or outside academia, and for which treatment would be welcome.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT05882565
- Testing
- A brief (14-day) online mindfulness intervention, Psychoeducation online
- Where
- Indonesia
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Ka Yan
Cachexia, Depression
Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer
RATIONALE: A computer-based system for assessing symptoms may be effective for patients with metastatic or advanced cancer. PURPOSE: This clinical trial is studying how well computerized questionnaires work in assessing symptoms…
- Conditions
- Cachexia, Depression, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00972634
- Testing
- computer-assisted intervention, questionnaire administration, assessment of therapy complications
- Where
- Norway
- Volunteers
- 1,051 people
- Sponsor
- Norwegian University of Science and Technology
Depressive Symptoms
Developing an Integrated Model for Home Visitation
Perinatal depression is a significant concern, particularly for low-income women. Many cases of perinatal depression are complicated by comorbidities such as post-traumatic stress disorder symptoms, anxiety, and intimate partner…
- Trial name
- NCT02410109
- Testing
- SCRIPT integrated model
- Where
- 2 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Diabetes, Depression, Cardiovascular Disease,Hypercholesterolemia, Osteoporosis
Use of Decision Aids in Clinical Encounters
The active strategy for dissemination and implementation of Share Evidence Based Medicine (EBM) will yield greater reach of clinicians, be adopted by the practices more readily, and a greater uptake of use amongst encounters will…
- Trial name
- NCT02136199
- Testing
- Active Implementation of ShareEBM Toolkit, Passive Dissemination of Share EBM
- Where
- 12 sites in United States
- Volunteers
- 62 people
- Sponsor
- Mayo Clinic
Depression, Anxiety
Retrospective Medical Record Review of Mind Body Depression Group Participants
The purpose of this study is to assess the effectiveness of a Relaxation Response Intervention for Depression offered to low income populations at Massachusetts General Hospital (MGH) - Chelsea, Revere and Charlestown health…
- Trial name
- NCT01909921
- Volunteers
- 156 people
- Sponsor
- Massachusetts General Hospital
Spinal Cord Injuries, Psychological Distress
A Guided Online ACT Intervention Combined With Psychoeducation for People With Spinal Cord Injury
The purpose of this preliminary study is to examine the effects of a guided online acceptance and commitment therapy (ACT) intervention combined with psychoeducation on people with spinal cord injury (SCI) who experience…
- Trial name
- NCT04670406
- Testing
- acceptance and commitment therapy (ACT) combined with psychoeducation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Depression
Implementation of Problem-Solving Treatment in Community Health Centers (PST-Aid)
Although evidence-based clinical interventions (CI) are a preferred treatment option for patients with depression, CIs are rarely available in community primary care settings.
- Trial name
- NCT06494384
- Testing
- Problem Solving Treatment as usual (PST as usual), Problem Solving Treatment Aid (PST-Aid)
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Washington
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