Clinical trials: Depression Symptom
Colorectal Cancer (CRC)
Normobaric Oxygen Therapy in Colorectal Cancer Patients
Colorectal cancer (CRC) patients undergoing chemotherapy often experience anemia, oxidative stress, and immune suppression, significantly impacting their quality of life and treatment outcomes.
- Trial name
- NBO-ONCO (NCT06946004)
- Testing
- Normobaric oxygen therapy
- Where
- Poland
- Volunteers
- 254 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Depression, Postpartum
The Impact of Creative Interventions on Symptoms of Postnatal Depression (Cohort Study)
Post-natal depression (PND) is anticipated to affect 12.9% of new mothers with at least 75,000 cases per year in the UK alone. However, despite this, there is currently a worrying lack of support for new mothers, with data…
- Trial name
- NCT02526433
- Where
- United Kingdom
- Volunteers
- 2,558 people, healthy volunteers welcome
- Sponsor
- Royal College of Music
Critical Care, Anxiety Depression
Participation of Relative or Surrogate in the Patient's Care in Reanimation
ICUs have always perceived by the public has a very technical unit with a restricted and/or forbidden access. Physical alteration of the patient, seeing the patient sedated, the large numbers of devices, the alarms and an…
- Trial name
- PARTICIPATE (NCT03090867)
- Testing
- Relatives or surrogates are encouraged to perform care, Conventional ,care
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity
Effects of Senobi Breathing Exercises in Obese Women
Previous studies have been done just in studying the relationship between breathing technique and obesity and described how it proved helpful in decreasing body fat.
- Trial name
- NCT05323500
- Testing
- Senobi breathing exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Depression, Anxiety
Evaluating a Single-session Mental Health Intervention for UK University Students
The investigators are evaluating if an online single-session intervention, the Common Elements Toolbox (COMET) can improve mental health and wellbeing among UK university students.
- Conditions
- Depression, Anxiety, Happiness
- Trial name
- NCT05093816
- Testing
- Common Elements Toolbox
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Post-stroke Depression
Efficacy of Accelerated Repetitive Transcranial Magnetic Stimulation on Patients With Post-stroke Depression
The FDA approved repetitive transcranial magnetic stimulation (rTMS) for patients with Major Depressive Disorder (MDD) in 2008. The conventional rTMS protocol that has been used effectively for major depression is 5 days per week…
- Trial name
- NCT06157333
- Testing
- The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Postmenopause, Overweight
Spirulina Supplementation in Postmenopausal Women
The purpose of this study is to investigate the effects of spirulina supplementation on weight gain associated with menopause, changes in metabolic parameters, sleep quality, and markers of depression in mildly overweight…
- Trial name
- NCT07718399
- Testing
- Spirulina
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Halic University
Insomnia, Depression
Digital Mood-enhanced CBT-I to Improve Depressive Symptoms in Adolescents
Emerging encouraging evidence showed that sleep focused treatment can simultaneously improve sleep and depression in adult with comorbid conditions.
- Conditions
- Insomnia, Depression, Adolescent
- Trial name
- NCT06358898
- Testing
- Standard dCBT-I, Modified Mood enhanced CBT-I (M-dCBT-I)
- Where
- Hong Kong
- Volunteers
- 343 people
- Sponsor
- Chinese University of Hong Kong
Stress Disorders, Post-Traumatic
Train Your Brain: Neurofeedback Intervention for PTSD
The investigator's aim is to evaluate the efficacy of two types of neurofeedback treatments for PTSD symptoms reduction. Half of the participants will receive the current standard for PTSD neurofeedback care undergoing…
- Trial name
- NCT03858933
- Testing
- eBrainFit Platform
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Southern California
Depression, Coronary Disease
Treatment of Depression After Coronary Bypass Surgery
This randomized controlled trial will test the efficacy of (1) cognitive behavior therapy and (2) supportive stress management as treatments for depression in people who have recently undergone coronary artery bypass graft…
- Trial name
- NCT00042198
- Testing
- Cognitive behavior therapy, Supportive Stress Management
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Washington University School of Medicine
Premenstrual Dysphoric Disorder
Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder
This study will evaluate the effectiveness of sertraline in reducing symptoms in women diagnosed with premenstrual dysphoric disorder.
- Trial name
- NCT00536198
- Testing
- Sertraline
- Where
- 3 sites in United States
- Volunteers
- 252 people
- Sponsor
- Yale University
Hemodialysis Patients
Mandala Colouring On Anxiety, Depression, Pain And Quality of Life
The research was conducted as an experimental research to determine the effect of mandala painting on pain, anxiety, depression and quality of life in patients undergoing hemodialysis.
- Trial name
- MANDALA (NCT06106763)
- Testing
- Mandala coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istanbul Sabahattin Zaim University
Depressive Disorder
Sensory Hyperstimulation for Treating Depression
Major depressive disorder (MDD) is associated with dysfunction across large-scale brain networks and remains insufficiently responsive to existing treatments in many patients.
- Trial name
- HSS (NCT07800663)
- Testing
- sensory hyperstimulation
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Shalvata Mental Health Center
Mild Cognitive Impairment, Anxiety State
Efficacy of Sublingual 5-MeO-DMT for Reducing Anxiety and Depression in MCI
This Phase I/II clinical trial aims to test the effectiveness of a new sublingual formulation of 5-MeO-DMT in reducing symptoms of anxiety, depression, and cognitive decline in individuals with mild to moderate Alzheimer's…
- Conditions
- Mild Cognitive Impairment, Anxiety State, Depression Anxiety Disorder
- Trial name
- 5-MeO-DMT (NCT06812221)
- Testing
- Sublingual administration, Electroencephalography, Biochemical mesurements
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Biomind Labs Inc.
Schizophrenia, Major Depression
Effect of Specific Anti-Toxoplasmatic Add-on Medication in Toxoplasma Gondii Seropositive Individuals With Schizophrenia or Major Depression
We investigate whether the add-on specific antitoxoplasmatic medication has positive effects in individuals with schizophrenia or major depression seropositive for Toxoplasma gondii (TG) infection.
- Trial name
- NCT00300404
- Testing
- daraprim, pyrimethamine, folinic acid
- Volunteers
- 40 people
- Sponsor
- Zentrum für Integrative Psychiatrie
Stroke, Depression
Post-Stroke Optimization of Walking Using Explosive Resistance
The investigators will study the effects of a 12 week strength training program on individuals who have had a stroke and are depressed to see if this type of exercise training helps treat depression and improves walking function.
- Trial name
- POWER-D (NCT03826771)
- Testing
- Power training, Stretching
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical University of South Carolina
Anxiety State, Depression
Stress Levels and Mental Well-Being Among Slovak Students During e-Learning
Introducing restrictions on human contact has been effective in preventing the uncontrolled spread of COVID-19, however, it appears to have negatively impacted mental health.
- Trial name
- NCT04924634
- Testing
- Stress Levels and Mental Well-Being assessment
- Where
- Poland
- Volunteers
- 3,051 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Post Traumatic Stress Disorder, Depression
Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees
INTRODUCTION Trauma-affected refugees are at high risk of developing mental health problems including post-traumatic stress disorder (PTSD) and depression.
- Conditions
- Post Traumatic Stress Disorder, Depression, Psychosocial Problem
- Trial name
- NCT04244864
- Testing
- Cross-sectoral psychosocial intervention, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 196 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Organ Transplantation, Anxiety
Systematic Evaluation of Predictors of Quality of Life in the Long-term After Solid Organ Transplantation
A systematic evaluation of predictors of health related quality of life (HRQoL) leads to multiple level of data analysis. The aim of the herein described observational project is to create a transplant patients registry on…
- Conditions
- Organ Transplantation, Anxiety, Depression
- Trial name
- NCT00792064
- Where
- Germany
- Volunteers
- 700 people
- Sponsor
- Hannover Medical School
Insomnia, Depression
Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)
Nearly half of women develop insomnia during pregnancy, which is associated with increased risk for developing perinatal depression.
- Trial name
- INSPIRE (NCT05356364)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBTI), Perinatal Understanding of Mindful Awareness for Sleep (PUMAS)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
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