Clinical trials: Depression Symptom
Major Depressive Disorder, Irritable Bowel Syndrome
Study of Probiotic GanedenBC30 for Irritable Bowel Syndrome and Major Depressive Disorder
The purpose of this study is to determine the safety and effectiveness of a nutritional supplement, the probiotic bacteria GanedenBC30.
- Trial name
- NCT01337609
- Testing
- Ganeden BC30
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Massachusetts General Hospital
Major Depression
Serum Markers as a Bioassay for Unipolar Depression
The goal of the study is to validate a biomarker assay for unipolar depression based on serum proteins involved in inflammation, metabolism, and stress response.
- Trial name
- NCT00825799
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Depression, Anxiety
T.E.A.M. Feasibility and Efficacy Study 2.0
T.E.A.M. psychotherapy was developed by one of the founders of cognitive therapy, David Burns and builds on traditional CBT with an emphasis on T = Testing, E = Empathy, A = Agenda Setting (assessing and building motivation) and…
- Trial name
- TEAM (NCT03694106)
- Testing
- TEAM PSYCHOTHERAPY
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Feeling Good Institute
Anxiety, Depression
Mental Health INtervention With Digital APPlications (MIND-APP): Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health Apps
The MIND-APP trial is a 3-arm randomized controlled trial (1:1:1 allocation) conducted fully remotely via a bespoke smartphone research platform.
- Trial name
- MIND-APP (NCT07627204)
- Testing
- Tankevirus, Grubl
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Akershus
Depression
Identifying and Treating Depression in the Orthopaedic Trauma Population
The goal of this trial is to pilot a way for orthopaedic surgeons to safely screen for depression and provide treatment for depression with medication. The main questions it aims to answer are: 1.
- Trial name
- NCT05976347
- Testing
- Fluoxetine 20 MG, Duloxetine 30 MG, Observation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
Mental Health Wellness 1
The Effects of Trauma-sensitive Yoga and Tai Chi on Mental Health
A three-arm randomized control trial design was used to test the effectiveness of (1) Chen Style Tai Chi (TC) and talk therapy; (2) Trauma-Sensitive Yoga and talk therapy in comparison to (3) talk therapy only (control group) on…
- Trial name
- TSY/TC (NCT04754009)
- Testing
- Trauma-Sensitive Yoga + TAU, Chen Style Tai Chi + TAU, Treatment as Usual
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Psychosis, Anxiety
Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis
The aim of this trial is to evaluate the feasibility and preliminary efficacy of using passive smartphone sensors to detect moments of heightened negative mood and inform the timing of brief mental health interventions, such as…
- Conditions
- Psychosis, Anxiety, Depression, Rumination
- Trial name
- NCT07503093
- Testing
- Smartphone-based Mindfulness Exercise, Smartphone-based Psychoeducation, Neutral Control Message
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mclean Hospital
Depression, Sleep
The Efficacy of the Caregiver Psychoeducational Consultation Program
Aim: To examine the effects of the caregiver psychoeducational consultation program in reducing caregiver burdens, depression, sleep quality, and improving the experience in close relationship, positive meaning of illness and…
- Trial name
- NCT01001884
- Testing
- caregiver psychoeducational consultation program (CPCP)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Lifestyle (Sedentary Behavior and Physical Activity), Mental Health
Lifestyle and Its Association With Maintaining Health
This study is part of the LIFEHEALTH project and will be carried out in five Mediterranean European Union countries: Croatia, Greece, Italy, Slovenia, and Spain.
- Conditions
- Lifestyle (Sedentary Behavior and Physical Activity), Mental Health, Nutrition, Sleep
- Trial name
- LifeHealth-OBS (NCT07309484)
- Where
- Croatia
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Zadar
Depression
A Computerized Depression Intervention in Veterans
Depressive symptoms are common among Veterans and associated with significant impairment. Timely intervention has the potential to improve mental health outcomes and restore functioning.
- Trial name
- Deprexis (NCT06217198)
- Testing
- Deprexis
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- VA Office of Research and Development
Perinatal Problems, Mental Depression
Effect of Perinatal Emotional Management on Maternal Emotion and Delivery Outcomes
Pregnancy or childbirth is a kind of persistent and strong source of stress for pregnant women. Prenatal and intrapartum negative emotions not only damage the mental health of pregnant women, but also have a negative impact on…
- Conditions
- Perinatal Problems, Mental Depression, Complications; Cesarean Section
- Trial name
- NCT01851187
- Testing
- antenatal psychological intervention, routine prenatal care
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Depression, Anxiety
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
The proposed study draws on prior research to evaluate the feasibility, acceptability and explore preliminary effectiveness of Coffee and Family Education and Support, Version (CAFES2) using a pilot randomized type 1 hybrid…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT06261463
- Testing
- CAFES2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Illinois Chicago
Bipolar Disorder, Depression
Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression
We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. Particularly, we are looking at the importance of inflammation in the process.
- Trial name
- NCT03730064
- Testing
- N-acetyl cysteine (NAC)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Martin Lan
Chronic Obstructive Pulmonary Disease (COPD), Anxiety
Pilot Study on Mindfulness Based Stress Reduction (MBSR) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This two-phase exploratory pilot study investigates the impact of a Mindfulness-Based Stress Reduction (MBSR) program on patients with chronic obstructive pulmonary disease (COPD) undergoing pulmonary rehabilitation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Anxiety, Depression Disorders, Stress
- Trial name
- NCT07593521
- Testing
- Mindulness Based Stress Reduction program
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Université Libre de Bruxelles
Post-stroke Depression
iPad Application-based Intervention for Post-stroke Depression
We plan to conduct a randomized controlled trial to examine whether usual rehabilitation plus an iPad application-based intervention improves post-stroke depression symptoms compared to usual rehabilitation alone.
- Trial name
- NCT03864484
- Testing
- iPad Application + Usual Rehabilitation, Usual rehabilitation
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Kibi International University
Sickle Cell Disease, Virtual Reality
Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD)
Patients with sickle cell disease (SCD) and cancer often have complicated courses while hospitalized and often deal with pain, anxiety and depression.
- Conditions
- Sickle Cell Disease, Virtual Reality, Anxiety, Depression
- Trial name
- NCT03387033
- Testing
- Relaxation response and virtual reality (VR) session
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Bipolar, Depression
Adjunctive Lisdexamfetamine (LDX) in Bipolar Depression
The specific aim of this study is to evaluate the efficacy and tolerability of lisdexamfetamine in the adjunctive treatment of bipolar disorder.
- Trial name
- NCT01131559
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lindner Center of HOPE
Depression
DNA-based Dietary Advice for Adults With Depressive Disorders
To evaluate the feasibility of nutrigenomics as an intervention for mental health conditions, a phase I randomized controlled trial of 42 adults (19 to 50 years) with depressive disorders using a 2:1 ratio of group selection (28…
- Trial name
- NCT03310827
- Testing
- Personalized Nutrition
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Karen Davison
Depressive Disorder, Major, Bipolar Disorder
Psychiatric Genotype/Phenotype Project Repository
The purpose of this project is to obtain DNA, brain imaging data, other biological samples (e.g., urine, serum), and a comprehensive clinical assessment on patients with schizophrenia and other psychotic disorders, bipolar…
- Conditions
- Depressive Disorder, Major, Bipolar Disorder, Psychotic Disorders
- Trial name
- PGPP (NCT00762866)
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Nursing Home Resident, Skilled Nursing Facility
Pilot Study of a Behavioral Program for Depression in Skilled Nursing Facility Residents and Care Partners
The goal of this clinical trial is to test a behavioral health program (Interventions for Stressful Transitions in Later Life, InSTILL) for skilled nursing facility residents and care partners.
- Conditions
- Nursing Home Resident, Skilled Nursing Facility, Depression, Feasibility Studies
- Trial name
- BRISK (NCT07891546)
- Testing
- Interventions for Stressful Transitions in Later Life (InSTILL)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.