Clinical trials: Depression Symptom
Depression, Depressive Disorder
A Single Group Study of Empower@Home-an Internet Cognitive Behavioral Therapy Intervention
This is a single group study of a novel internet-based cognitive behavioral therapy program for older adults with elevated depressive symptoms.
- Conditions
- Depression, Depressive Disorder, Behavioral Symptoms, Mood Disorders
- Trial name
- NCT05384704
- Testing
- Empower@Home
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Michigan
Hypercapnia, Ventilatory Depression
Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation
This study is designed to evaluate the effects of the coadministration of paroxetine or escitalopram with an opioid on ventilation. Ventilation will be assessed using a rebreathing methodology.
- Trial name
- NCT05470465
- Testing
- Paroxetine and Oxycodone, Escitalopram and Oxycodone
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)
Cocaine-Related Disorders, Substance-Related Disorders
New Approaches to Cocaine Abuse Medications (A) - 6
The purpose of this study is to measure the effect of desipramine in cocaine abusers selected for major depression or dysthymia.
- Trial name
- NCT00000271
- Testing
- Desipramine
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- New York State Psychiatric Institute
Psychopathology, Child Mental Health
Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function
Growing up in a lower-income family robustly predicts worse mental health in adolescence and early adulthood. How does variability in family income "get under the skin" of the developing child and via what mechanisms does it…
- Conditions
- Psychopathology, Child Mental Health, Anxiety Disorders, Mental Disorders
- Trial name
- NCT07641244
- Testing
- Psychological fMRI task
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Northwestern University
Depression, Anxiety
Progressive Muscle Relaxation in Nursing Students: Effects on Psychological and Biopsychosocial Outcomes
This randomised controlled trial aims to investigate the effects of progressive muscle relaxation exercises (PMRE) on depression, anxiety, stress, future-oriented attitudes, and biopsychosocial responses in nursing students.
- Conditions
- Depression, Anxiety, Stress, Psychological, Mental Health
- Trial name
- PRMNURSE (NCT07038109)
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Depression, Postpartum, Postpartum Depression (PPD)
Brexanolone Lifting Outcomes Of Moms
The purpose of this research study is to test the study drug, LPCN 1154A, as a possible treatment for postpartum depression (PPD).
- Conditions
- Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression
- Trial name
- BLOOM (NCT07822321)
- Testing
- LPCN 1154A
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Lipocine Inc.
Memory Dysfunction, Anxiety
Effects of Orally Administered Thymus Vulgaris Leaves on Memory, Anxiety, Depression, and Sleep Quality in University Students: A Randomized Controlled Trial
Thymus vulgaris could potentially serve as a safer alternative to stimulant drugs for enhancing memory among university students.
- Conditions
- Memory Dysfunction, Anxiety, Depression, Sleep
- Trial name
- NCT05987228
- Testing
- Thymus vulgaris
- Where
- Jordan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Cognitive Impairment, Dementia
Determinants of Cognitive Impairment Among Geriatrics
This study aims to explore the determinants of cognitive impairment among Indonesian geriatrics in an Old Age Home.
- Conditions
- Cognitive Impairment, Dementia, Hearing Impairment, Vision Impairment and Blindness
- Trial name
- NCT03669536
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Depression, Ketosis
Ketogenic Intervention in Depression
The goal of this study is to examine whether a well-formulated ketogenic diet (KD) can be implemented into a university counseling treatment program for major depression and to test whether such a program has any benefit on…
- Trial name
- KIND (NCT06080932)
- Testing
- Ketogenic Diet, NIH Toolbox, gradCPT
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Anxiety, Depression
NeuroGlove Anxiety and Depression Study
This is a prospective, homebased, interventional clinical study containing 10 subjects who will be enrolled. Approximately 10 (10) subjects with active anxiety and depression symptoms will receive treatment using the NeuroGlove.
- Conditions
- Anxiety, Depression, Anxiety Depression, Depression, Anxiety
- Trial name
- NCT06065787
- Testing
- NeuroGlove
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NeuroGlove LLC
Anxiety, Depression
CALM for Pregnant and Post-Partum Women
Anxiety and depression is common along pregnant mothers and has been found to increase risk for negative outcomes in both mothers and infants.
- Conditions
- Anxiety, Depression, Depression, Postpartum, Pregnancy Related
- Trial name
- NCT03351465
- Testing
- Coordinated Anxiety Learning and Management
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anal Cancer, Anxiety Disorder
Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer Either in a Clinical Trial or as Standard Off-Trial Therapy
RATIONALE: Gathering information from patients who received treatment for metastatic cancer while participating in a phase II or phase III randomized clinical trial and from patients receiving standard treatment off-trial may…
- Conditions
- Anal Cancer, Anxiety Disorder, Breast Cancer, Depression
- Trial name
- NCT00896467
- Testing
- questionnaire administration, psychosocial assessment and care, quality-of-life assessment
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Oscar Lambret
Pain, Postoperative, Pain Uterus
Effects of Tapentadol Versus Oxycodone After Hysterectomy.
Opioids remain the first-line drugs for the treatment of moderate to severe postoperative pain, but the use is limited by well-known side-effects, most of which are dose-dependent.
- Conditions
- Pain, Postoperative, Pain Uterus, Pain, Acute, Opioid Use
- Trial name
- NCT03314792
- Testing
- Tapentadol, Oxycodone
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Oslo University Hospital
Irritable Bowel Syndrome (IBS), Anxiety
Anxiety and Depression in IBS: A Brain-Gut Axis Study
This study aims to understand how the gut and the brain communicate in people with Irritable Bowel Syndrome (IBS) who also experience anxiety and depression.
- Conditions
- Irritable Bowel Syndrome (IBS), Anxiety, Depression
- Trial name
- NCT07646834
- Testing
- Observational Study (No Intervention)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Psychiatric Disorder, Memory Disorders
Neural Correlates of Psychiatric Disorders
This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037.
- Trial name
- NCT04725409
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Anxiety, Depression
A Mobile Health Solution for Homework During CBT
The purpose of this study is to preliminarily evaluate a web-based app to improve provider implementation and patient engagement in homework (i.e., between-session practice of skills learned during therapy) during child mental…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- NCT04931199
- Testing
- Cognitive Behavioral Therapy (CBT), CBT+App
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of South Florida
Depression, Involutional, Healthy
Serotonin Function During Depression
Serotonin is a chemical involved in regulation of emotions, anxiety, sleep, stress hormones, and other body functions. The purpose of this study is to use a procedure called tryptophan depletion to study the function of serotonin…
- Trial name
- NCT00033787
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Major Depressive Disorder
Predictors of Depression Treatment Response to Exercise
50 subjects with Major Depressive Disorder who are not currently receiving treatment will be enrolled in a 12-week exercise program, supervised by a trained exercise interventionist.
- Trial name
- NCT02583867
- Testing
- Exercise
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Anxiety
Depression and Anxiety in the Aetiology and Prognosis of Specific Cardiovascular Disease Syndromes: a CALIBER Study
People report feeling sad and low (depression) or worried (anxiety) appear more likely to subsequently suffer a heart attack, or angina. However it is not known whether depression or anxiety actually causes heart disease.
- Conditions
- Depression, Anxiety, Coronary Disease, Cardiovascular Disease
- Trial name
- NCT01240798
- Where
- United Kingdom
- Sponsor
- University College, London
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