Clinical trials: Depression Symptom
Depression, Depressive Disorder, Major
Feasibility of a Technology-Based Treatment Support System
This study aims to evaluate a technology-based treatment support system for patients undergoing the treatment of depression. The investigators will explore the usefulness of the technology-based treatment support system as an…
- Trial name
- NCT03121937
- Testing
- Mobile App
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Northwestern University
Traumatic Brain Injury, Depression
The Effect of Exercise on Mood After Traumatic Brain Injury
We proposed to examine the effect of an aerobic exercise intervention on depression in persons with Traumatic Brain Injury (TBI).
- Trial name
- NCT00571545
- Testing
- Aerobic exercise, No exercise
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
Psychogenic Non-Epileptic Seizure, Depression
Project UPLIFT for Psychogenic Non-Epileptic Seizures
Developed by researchers from the Centers for Disease Control and Prevention (CDC), Project UPLIFT (Using Practice and Learning to Increase Favorable Thoughts) is a group telephone program designed to improve depression for…
- Conditions
- Psychogenic Non-Epileptic Seizure, Depression, Non-Epileptic Seizure, Psychogenic Seizure
- Trial name
- PNES (NCT03329703)
- Testing
- Project UPLIFT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Depression
Repetitive Transcranial Magnetic Stimulation (rTMS) in Depression
This study will report on the outcomes of rTMS administered 3 times per week, compared with the standard protocol of 5 times per week.
- Trial name
- NCT00920322
- Testing
- rTMS 5 x weekly, rTMS 3 times weekly
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Northside Clinic, Australia
Depression
RCT of Adjunctive Curcumin and the Meru Health Program
This is a randomized controlled trial (RCT) to compare the Meru Health Program plus adjunctive curcumin (MHP-CUR) versus Meru Health Program only (MHP-ONLY) for adults with depression.
- Trial name
- NCT04744545
- Testing
- Meru Health Program, Curcumin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meru Health, Inc.
Bipolar Disorder, Bipolar Depression
Seroquel in Bipolar Depression Versus Lithium
This study is being carried out to see if quetiapine fumarate (Seroquel) is effective in treating bipolar depression during an 8-week acute phase compared with placebo and lithium, followed by continuation treatment for 26 up to…
- Conditions
- Bipolar Disorder, Bipolar Depression, Depression
- Trial name
- NCT00206141
- Testing
- Quetiapine Fumarate (Seroquel™) drug, mood stabilizer (mood)
- Where
- 76 sites in Canada, Croatia and 14 more
- Volunteers
- 672 people
- Sponsor
- AstraZeneca
Depression
Effectiveness and Cost-effectiveness of Telephone-delivered Psychotherapy for Depression in Primary Care
The aim of the study is the examination of effectiveness and cost-effectiveness of a telephone-based psychotherapy (Tel-PT) for depression compared to treatment as usual in primary care.
- Trial name
- NCT02667366
- Testing
- Tel-PT, TAU and text messages
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- University of Zurich
Depression, Anxiety
Feasibility of Egg-Based Diet Interventions and Assessing Perinatal Mental Health
The goals of this study are to assess the feasibility and acceptability of a dietary intervention to increase choline intake through whole foods (eggs) in pregnant and lactating women for mental health benefits.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- NCT05619445
- Testing
- Whole Liquid Egg, Plant-based Egg Substitute
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Suicide Awareness, Suicidal Ideation
"Youth Aware of Mental Health" in Galicia
The goal of this interventional study is to assess the effectiveness of the universal suicide prevention program "Youth Aware of Mental Health" in 3rd-year secondary education students in Galicia.
- Conditions
- Suicide Awareness, Suicidal Ideation, Suicide, Attempted, Depressive Symptoms
- Trial name
- YAM (NCT06251037)
- Testing
- Youth Aware of Mental Health in Galicia
- Where
- 68 sites in Spain
- Volunteers
- 4,453 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
NSCLC, Anxiety Postoperative
Influence of a PSychological Intensive Support Program for Lung Cancer Patients ON Post-operative Outcomes.
Anxiety is common among patients diagnosed with lung cancer, affecting 50-60% of cases, and over 30% report moderate to severe psychological distress.
- Conditions
- NSCLC, Anxiety Postoperative, Depression
- Trial name
- IPSILON (NCT07260227)
- Testing
- HADS (Hospital Anxiety and Depression Scale)
- Volunteers
- 138 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bipolar Disorder
Prevention of Relapse & Recurrence of Bipolar Depression
The purpose of this study is to determine whether the long-term use of combined antidepressant plus mood stabilizer therapy is superior to mood stabilizer therapy alone in preventing the relapse and recurrence of bipolar…
- Trial name
- NCT00961961
- Testing
- Lithium / Fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 177 people
- Sponsor
- University of Pennsylvania
Depressive Symptoms, Emotion Regulation
Making SPARX Fly in Nunavut: Pilot Testing an E-intervention for Boosting Resilience Against Youth Depression
The goal of this pilot trial was to test SPARX with Inuit youth in Northern Canada. SPARX is an educational video game designed to teach cognitive behavioural therapy strategies and techniques.
- Trial name
- NCT05702086
- Testing
- SPARX (Smart, Positive, Active, Realistic, X-Factor thoughts)
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- York University
Frailty Syndrome
TrackFrailty Project
The TRACKFRAILTY project aims to answer the following main research questions: i) What is the prevalence of physical frailty in individuals living in residential care facilities (RCF) from Portugal's Cova da Beira subregion…
- Trial name
- TrackFrailty (NCT06812286)
- Testing
- Less-volume, More-volume, Control
- Where
- 6 sites in Portugal
- Volunteers
- 45 people
- Sponsor
- University of Beira Interior
Pregnancy Distress
E-health Intervention in Women With Pregnancy Distress
The study aims to reduce the levels of distress (depression and anxiety) during pregnancy. The study investigates the effectiveness of an eHealth pregnancy distress-reducing mindfulness training in women with pregnancy distress.
- Trial name
- NCT03917745
- Testing
- eHealth mindfulness intervention
- Where
- Netherlands
- Volunteers
- 219 people
- Sponsor
- Tilburg University
Depression, Bipolar Disorder
Neuro-computational Study of Thymic Fluctuations in Mood Disorders
Depression and bipolar disorder are frequent, debilitating conditions. Both are thought to be primarily caused by an impaired regulation of mood, which is why they are sometimes referred to as "mood disorders".
- Conditions
- Depression, Bipolar Disorder, Recurrent Depression, Mood Disorders
- Trial name
- MOODELING (NCT07033923)
- Testing
- Brain magnetic resonance imaging (MRI) with structural (anatomical) and functional sequences (optional), Computerized cognitive tests, Daily longitudinal monitoring by mobile MOODELING application
- Where
- 2 sites in France
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Periodontitis, Depression
Periodontal Assessment in Depression Patients
To assess the periodontal status in the patients with depression. Evaluation of periodontal status in patients with mild depression. Evaluation of periodontal status in patients with moderate depression.
- Trial name
- NCT04260880
- Testing
- periodontal status in mild depression patients, periodontal status in moderate depression patients, periodontal status in systemically healthy patients
- Where
- India
- Volunteers
- 135 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Major Depressive Disorder
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
The goal of this clinical trial is to learn if zelquistinel works to treat depression in adults. It will also learn about the safety of zelquistinel.
- Trial name
- GATE-251 (NCT07115329)
- Testing
- Zelquistinel
- Where
- 32 sites in United States
- Volunteers
- 164 people
- Sponsor
- Syndeio Biosciences, Inc
Emotional Well-being
iCBT to Promote Emotional Well-being in University and Research Communities: Feasibility and Acceptability Study
This study will evaluate a brief internet-based cognitive behavioral therapy (iCBT) program developed specifically for university students, researchers, and academic staff.
- Trial name
- iCBT-Academia (NCT07082296)
- Testing
- iCBT-Academia
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Joaquim Radua
Depressive Disorder, Major
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-911 in Healthy Subjects
This is a Phase 1, conventional, double-blind, placebo-controlled, single-center clinical study comprised of 2 segments (Segment 1 and Segment 2) in which single and multiple doses of SUVN-911 or placebo will be orally…
- Trial name
- SUVN-911 (NCT03155503)
- Testing
- SUVN-911
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Suven Life Sciences Limited
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
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