Clinical trials: Depression Symptom
Laughter Yoga
The Effect of Group-Based Laughter Yoga on Midwifery Students
This study was planned to determine the effect of laughter yoga on the secondary traumatic stress and depression levels experienced by midwifery students due to the use of social media after the earthquake.
- Trial name
- NCT05942131
- Testing
- Group-based laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Depression
Effect of Low-dose Esketamine on Postoperative Depression in Patients With Breast Cancer
esketamine is an optical isomer of ketamine. Compared with ketamine, esketamine has the characteristics of higher effective value, stronger receptor affinity, less adverse reactions of nervous system, and pharmacokinetics is…
- Trial name
- NCT04850937
- Testing
- Esketamine, normal saline
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yangzhou University
Stress Disorders, Post-Traumatic
Psychological Symptom Change in Veterans After Six Sessions of EFT (Emotional Freedom Techniques)
EFT (Emotional Freedom Techniques) has been shown to significantly reduce post-traumatic stress disorder (PTSD) and other psychological symptoms such as anxiety and depression in a variety of clinical trials.
- Trial name
- NCT01117545
- Testing
- EFT (Emotional Freedom Techniques)
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Cancer Diagnosis, Non-Metastatic Neoplasm
PRISM for Depression and Anxiety in Young Adults With Cancer
This research study is being done to test the feasibility of an existing supportive program (PRISM) to address psychological symptoms (i.e., depressive and anxiety symptoms) that young adult participants diagnosed with cancer or…
- Conditions
- Cancer Diagnosis, Non-Metastatic Neoplasm, Anxiety, Anxiety Disorders
- Trial name
- PRISM (NCT06502483)
- Testing
- Promoting Resilience in Stress Management Program
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Dana-Farber Cancer Institute
Depression and/or Anxiety Symptoms
Replication: Meaning-centered Intervention for Internalizing Symptoms
Young adults who experience depression and/or anxiety symptoms (i.e., internalizing symptoms) will be randomly allocated to a six-session meaning-centered intervention condition or a waitlist condition.
- Trial name
- NCT07714954
- Testing
- Meaning-centered intervention for individuals who tend to feel down or anxious
- Volunteers
- 140 people
- Sponsor
- University of Groningen
Major Depressive Disorder, Cognitive Dysfunction
Musical Attention Control and Executive Function Training for Adults With MDD
The investigators have developed music-based cognitive training sessions derived from Neurologic Music Therapy (NMT) techniques.
- Conditions
- Major Depressive Disorder, Cognitive Dysfunction, Suicide
- Trial name
- NCT05694156
- Testing
- Music-based cognitive training
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Unity Health Toronto
Depression, Comorbid Personality Disorders
Effects of Vagus Nerve Stimulation (VNS) as a Treatment of Persistent Depression With Comorbid Personality Disorders (Impulse-VNS
In this monocentre two-armed double blind randomised placebo-controlled study - in which the control group obtains the VNS therapy within a defined space of time after 12 weeks - the impact of vagus nerve stimulation on…
- Trial name
- Impuls-V (NCT01119053)
- Testing
- VNS Pulse Model 102
- Where
- Germany
- Sponsor
- University Medical Center Goettingen
Depression, Diabetes Mellitus
Myelin, Glia and Depression in Type 2 Diabetes
The purpose of the study is to examine the relationship between brain structure and depression in adults aged 30 or older with Diabetes.
- Trial name
- NCT01327404
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Depression
Postmarketing Clinical Trial of tDCS to Evaluate Cognitive Ability in Depression Patients
This study is a multicenter, double-blind, randomized, and confirmed clinical trial in patients taking antidepressants during the 6-week stimulation period , sham stimulation group, low real stimulation group (1mA), high real…
- Trial name
- NCT04709952
- Testing
- Transcranial direct current stimulation_High real, Transcranial direct current stimulation_Low real
- Where
- 2 sites in South Korea
- Volunteers
- 141 people
- Sponsor
- ji hyun baek, MD, Ph.D
Depression
Cognitive Bias Modification (CBM) and Internet Cognitive Behavioural Therapy (iCBT) for Depression- A Randomised Controlled Trial
Cognitive accounts of depression and anxiety emphasize the importance of cognitive biases in the maintenance of disorders. One specific bias is the interpretation of ambiguous information.
- Trial name
- NCT01488058
- Testing
- OxIGen + iCBT, Waitlist Control
- Where
- Australia
- Volunteers
- 69 people
- Sponsor
- Alishia Williams
Major Depressive Disorder
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
The study will consist of a 24-week-long trial examining outcomes in patients with Major Depressive Disorder and suicidal ideation who will receive intravenous (IV) ketamine and intranasal (IN) esketamine, compared to a large…
- Trial name
- NCT05450432
- Testing
- Ketamine, Esketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation
Effect of Perimenstrual Ovarian Steroid Supplementation on Perimenstrual Suicidality
This within-person, crossover, 2-condition, placebo-controlled study compares the impact of two perimenstrual conditions on severity of suicidal symptoms in females with past-month suicidality but minimal risk of imminent suicide…
- Trial name
- NCT03720847
- Testing
- Estradiol Transdermal Patch 0.1 mg/24 hrs, Oral Micronized Progesterone, Inactive Clear Patch
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder, Dysthymia
Dichotic Listening as a Predictor of Medication Response in Depression
This study will recruit 100 depressed patients to test whether the previous finding of an association between treatment response (with treatment groups including placebo, imipramine, and fluoxetine) and preferences of hemispheric…
- Trial name
- NCT00404755
- Testing
- escitalopram, bupropion, imipramine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- New York State Psychiatric Institute
Heart Failure, Depression
Assessing the Acceptability and Feasibility of COMPASS
Heart failure (HF) is a complex clinical syndrome characterized by the inability of the heart to pump an adequate amount of blood.
- Conditions
- Heart Failure, Depression, Anxiety
- Trial name
- NCT05081947
- Testing
- COMPASS
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- King's College London
Major Depressive Disorder
Single IV Dose of GLYX-13 in Patients With Treatment-Resistant Depression
The purpose of this study is to determine whether GLYX-13 reduces depression score in patients with treatment-resistant depression.
- Trial name
- NCT01234558
- Testing
- GLYX-13
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Naurex, Inc, an affiliate of Allergan plc
Gestational Diabetes Mellitus
Improving Cardio-metabolic and Mental Health in Women With Gestational Diabetes Mellitus and Their Offspring
MySweetHeart Trial is a randomized controlled trial to test the effect of a multidimensional interdisciplinary lifestyle and psychosocial intervention to improve the cardio-metabolic and mental health of women with GDM and their…
- Trial name
- MySweetHeart (NCT02890693)
- Testing
- interdisciplinary lifestyle and psychosocial intervention
- Where
- Switzerland
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Bipolar Disorder, Major Depressive Episode
Ketamine for Suicidality in Bipolar Depression
This study is designed to compare the effectiveness of two medications, Ketamine and Midazolam, for rapidly relieving suicidal thoughts in people suffering from bipolar depression.
- Conditions
- Bipolar Disorder, Major Depressive Episode, Suicidal Ideation
- Trial name
- NCT01944293
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- New York State Psychiatric Institute
Osteoarthritis, Knee
Effects of Strength Training on Knee Osteoarthritis
To understand the effects of leg strengthening exercise, we will study the effects of strength training of the legs in four groups of people: (1) osteoarthritis (OA) with knee pain; (2) OA without knee pain; (3) no OA but elderly…
- Trial name
- NCT00000406
- Testing
- Progressive resistance exercise
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Indiana University
Depression
Effectiveness of Web-based Treatment for Depression in Patients With Neurologic Disorders
200 persons (100 with multiple sclerosis and 100 with epilepsy) with depressive symptoms are recruited via the multiple sclerosis clinics of the University Medical Center Hamburg-Eppendorf and the epilepsy centre Alsterdorf and…
- Trial name
- NCT01663649
- Testing
- Deprexis, Wait-list
- Where
- 2 sites in Germany
- Volunteers
- 180 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Alcohol-Related Disorders
VR Assessment for Alcohol Related Brain Damage
Pilot study where 10 alcohol-related brain damage (ARBD) patients will undergo a 30-minutes-long cognitive assessment session using the Validation Gate task to evaluate usability of this tool in Alcohol Use Disorder patients.
- Trial name
- NCT03826238
- Testing
- Validation Gate task
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Pompeu Fabra
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