Clinical trials: Depression Symptom
Depression, Postpartum
CODEPAD-III (Collaborative Outcomes of DEpression and Pain Associated With Delivery-III)
The childbirth process is associated with increased risk of having depression and persistent pain which may have adverse effects to mothers and their babies.
- Conditions
- Depression, Postpartum, Pain, Mental Health
- Trial name
- CODEPAD-III (NCT07773259)
- Testing
- Collaborative Psychological Model (CPM), Intervention common to both arms, Telephone-based support (Control)
- Volunteers
- 3,470 people
- Sponsor
- KK Women's and Children's Hospital
Burnout
Reducing Burnout Among Frontline Healthcare Workers During COVID-19
Physician burnout has a significant impact on the wellness and productivity of physicians as well as patient health outcomes. Managing burnout among frontline workers is critical to Canada's response to the COVID-19 pandemic, in…
- Trial name
- RESTORE (NCT04474080)
- Testing
- Virtual Peer Support Platform, Control Period
- Where
- Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Depression
Antidepressant Adherence for Depressed Adults in Primary Care
The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.
- Trial name
- NCT06496646
- Testing
- Arm 1 intervention, Arm 2 Intervention
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- University of Pennsylvania
Depression
Nurse-led Case Management for Diabetes and Cardiovascular Disease Patients With Depression
This study will evaluate the effectiveness of a nurse-led case management intervention in improving disease control and depression symptoms in adults with diabetes and/or heart disease who are also depressed.
- Trial name
- NCT00468676
- Testing
- Nurse-led case management, Treatment as usual
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- University of Washington
Depression Disorder, Anxiety
Impact of Nut Consumption on Mental Health in Young Adults
Nuts have a high nutrient density, and numerous studies have reported their cardiometabolic benefits. Although observational studies in adults have indicated a potential link between nut consumption and improved mental health…
- Conditions
- Depression Disorder, Anxiety, Mental Health, Stress
- Trial name
- NUTS4BRAIN-RCT (NCT07292610)
- Testing
- mixed nuts. Group A, mixed nuts. Group B, control group
- Where
- Spain
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Borderline Personality Disorder
Selective Serotonin Reuptake Inhibitors (SSRIs) in Borderline Personality Disorder
The goal of this study is to examine the effectiveness the selective serotonin reuptake inhibitor (SSRI) escitalopram (also known by the trade name "Lexapro") in reducing desire to self-harm and actual self-harming among young…
- Trial name
- NCT01103180
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Chicago
Depression
Reboxetine Treatment in Depressed Children and Adolescents an 8-Week, Open Study
The aim of the present study is to prospectively assess the anti-depressant effectiveness of reboxetine in children and adolescents, as compared with fluoxetine, in a randomized controlled open-label trial.
- Trial name
- NCT00426946
- Testing
- Reboxetine
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Geha Mental Health Center
Depressive Symptoms, Anxiety
Evaluating an Online Wellness Intervention for Indian College Students
We are evaluating the effects of an online single-session mental health intervention (the Common Elements Toolbox; COMET). To evaluate COMET, we are conducting a randomized controlled trial with Indian college students.
- Conditions
- Depressive Symptoms, Anxiety, Happiness
- Trial name
- NCT04592588
- Testing
- Common Elements Toolbox, Wait-list control
- Where
- 2 sites in India
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Parkinson Disease, Depressive Symptoms
Online Cognitive Behavioral Therapy for Depressive Symptoms in Parkinson's Disease
More than 1 million people in Europe suffer from Parkinson's disease (PD), a brain disorder manifesting with a motor syndrome and several non-motor features.
- Conditions
- Parkinson Disease, Depressive Symptoms, Anxiety
- Trial name
- ePark (NCT05585827)
- Testing
- Online cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Helse Stavanger HF
Morbid Obesity, Opioid-Related Disorders
Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients
This is an observational study of morbidly obese patients recovering from general anesthesia after weight-loss surgery. The investigators aim to assess ventilatory function and how this is influenced by the diagnosis of…
- Conditions
- Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
- Trial name
- NCT03925610
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Major Depressive Disorder, Alzheimer Disease
Home-based Neuromodulation to Target Depression And Memory Symptoms in Older Adults
This project aims to explore the feasibility and effects of a symptom-specific, brain-circuit-based, home-based neuromodulation therapy for addressing mood and memory symptoms in older adults with major depressive disorder (MDD)…
- Conditions
- Major Depressive Disorder, Alzheimer Disease, Dementia, Nervous System Diseases
- Trial name
- NCT05976659
- Testing
- Transcranial direct current stimulation (tDCS); Transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hebrew SeniorLife
Mental Stress, Anxiety
Effects of a Virtual Reality Intervention on Mental Health Outcomes and Academic Success in Physical Therapy Students
Exploring the impact of a virtual reality program, First Resort on graduate physical therapy student wellness and academic success.
- Conditions
- Mental Stress, Anxiety, Depression, Satisfaction
- Trial name
- NCT06567496
- Testing
- First Resort
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Belmont University
Major Depressive Disorder
Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents
To evaluate the safety and efficacy of daily, active Neurostar® TMS (when compared with sham treatment) in adolescents meeting criteria for Major Depressive Disorder (MDD).
- Trial name
- NCT02586688
- Testing
- Active NeuroStar® Transcranial Magnetic Stimulation (TMS)
- Where
- 13 sites in United States
- Volunteers
- 112 people
- Sponsor
- Neuronetics
Anxiety, Depression
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Depression and anxiety disorders rank in the top ten causes of years lived with disability. Less than 50% of patients experiencing long-lasting improvements to current gold-standard treatments.
- Trial name
- AAC-BeT (NCT04426461)
- Testing
- Behavioral Activation, Exposure-based therapy, Supportive therapy
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Depression
Computerized Cognitive Behavioral Therapy and Electroconvulsive Therapy
In an open-label feasibility study, fifteen will be recruited to participate in the study from among those who have already chosen of their own accord to undergo ECT (standard of care) at Yale Psychiatric Hospital for treatment…
- Trial name
- NCT02176473
- Testing
- Computerized Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Mental Health Disorder, Depression
Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19
This study aims at evaluating the effectiveness of a mobile phone based intervention to prevent and manage mental health problems in healthcare workers at the frontline against COVID-19 in Spain.
- Conditions
- Mental Health Disorder, Depression, Posttraumatic Stress Disorder, Burnout
- Trial name
- PsyCovid_App (NCT04393818)
- Testing
- Intervention App
- Where
- Spain
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Depression
Unilateral Massage as a Potential Treatment for Depression
In depression, EEG studies have shown frontal asymmetry with relatively lower activity in the left hemisphere. In this study a moderate pressure massage will be conducted by a trained professional on one of the following…
- Trial name
- NCT01937897
- Testing
- Bi-lateral massage
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Older Adults, Depression
Educational and Cultural Engagement and Incidence of Health Adverse Events
This study evaluated if the social and cultural activities decrease the incidence of dementia and frailty conditions.
- Conditions
- Older Adults, Depression, Cognitive Decline
- Trial name
- NCT03987360
- Testing
- Observational
- Where
- Canada
- Volunteers
- 30,000 people
- Sponsor
- Jewish General Hospital
Depression, Generalized Anxiety
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic
Study description: The present study seeks to investigate the impact of various sources of information on psychopathology, and specifically health anxiety, depression, and general anxiety, during the COVID-19 pandemic.
- Conditions
- Depression, Generalized Anxiety, Health Anxiety
- Trial name
- NCT04442360
- Testing
- Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Dysthymic Disorder, Depressive Disorder NOS
Duloxetine for Chronic Depression: a Double-blind Study
The investigators are studying a new antidepressant medicine, duloxetine, for the treatment of people with chronic depression. Duloxetine (trade name Cymbalta) was recently approved by the FDA for the treatment of major…
- Trial name
- NCT00360724
- Testing
- Duloxetine (Cymbalta)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- New York State Psychiatric Institute
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