Clinical trials: Depression Symptoms
Major Depressive Disorder (MDD)
The Effect of Transcranial Magnetic Stimulation Treatment on Microvasculature Stracture of the Retina and the Choroid
Transcranial Magnetic Stimulation (TMS) therapy is an approved and effective treatment option in treatment-resistant depression.
- Trial name
- TMS_OCT-A (NCT06708013)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Depression
MRI Imaging of Chronobiologic Abnormalities in Depression
The purpose of the study is to identify and understand patterns of brain activity when people are depressed. The study will use an imaging method called Magnetic Resonance Imaging (MRI) which does not involve any exposure to…
- Trial name
- NCT00178880
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Depression, Mania
Impact of Closely Grouped, Iterative Exposures to Suxamethonium During ECT on the Sensitization to NMBA and the Development of Protective Antibodies
Acute per-anesthetic hypersensitivity reaction (HSA-PA) is a rapidly occurring systemic reaction following injection of a drug during anesthesia (mortality between 3 and 9%).
- Conditions
- Depression, Mania, Hallucinations
- Trial name
- SismoSens (NCT05210062)
- Testing
- Iterative exposure to suxamethonium during ECT sessions
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression
Probiotic Administration for Adolescent Depression
This double-blind, placebo-controlled clinical trial will examine the effect of probiotic Visbiome on the brain and gut microbiome of individuals 15 to 24 years of age.
- Trial name
- PAD (NCT06898788)
- Testing
- Visbiome
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of California, San Francisco
Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline), Pain
Effect of Acupuncture on Psychoneurological Symptom Cluster in Breast Cancer Survivors
This clinical trial aims to assess whether electroacupuncture (EA) can alleviate the psychoneurological symptom cluster (including pain, fatigue, insomnia, anxiety, depression and subjective cognitive decline) in breast cancer…
- Conditions
- Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline), Pain, Insomnia, Anxiety
- Trial name
- NCT07481903
- Testing
- electroacupuncture
- Where
- 6 sites in China
- Volunteers
- 228 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Convulsion, Non-Epileptic, Conversion Disorder
Treatment Trial for Psychogenic Nonepileptic Seizures
The investigators propose that patients who receive targeted pharmacotherapy (sertraline) or focused psychotherapy (cognitive behavioral therapy-informed psychotherapy (CBT-ip) for NES) or combined treatment (CBT-ip + sertraline)…
- Conditions
- Convulsion, Non-Epileptic, Conversion Disorder, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NEST-T_1 (NCT00835627)
- Testing
- sertraline, CBT-ip, Combined (sertraline + CBT-ip)
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Mental Health Impairment, Mental Health
Mental Health in Dancers; an Intervention Study
International studies reveal high prevalence of eating disorders (ED) and mental health issues amongst professional dancers, and the Norwegian National Ballet's house previously (2005) reported a lifetime prevalence of ED by 50%…
- Conditions
- Mental Health Impairment, Mental Health, Eating Disorders, Perfectionism
- Trial name
- MeHeDa (NCT04085861)
- Testing
- Mental health literacy in dancers, Mental health literacy in dance teachers
- Where
- Norway
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Depression, Anxiety, Mindful Walking Meditation
Study on the Intervention of Mindfulness-integrated Volleyball Course
The purpose of this clinical trial is to understand whether a mindfulness-integrated volleyball team sports program can effectively intervene in the mental health of college students, and whether it has better intervention…
- Trial name
- NCT06600373
- Testing
- Mindful Walking meditation, physical education group class
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Ye Zhiyin
Functional Disability, Dementia
Aspirin in Reducing Events in the Elderly
ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants [ASPREE Investigator Group, 2013; www.aspree.org; McNeil et al 2017].
- Conditions
- Functional Disability, Dementia, Heart Disease, Stroke
- Trial name
- ASPREE (NCT01038583)
- Testing
- 100 mg enteric-coated aspirin
- Where
- 47 sites in United States, Australia
- Volunteers
- 19,114 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Anxiety State, Depression
Comparison of Physical and Virtual Sensory Room in an Inpatient Setting
Sensory room is a new method in psychiatric inpatient care for management of anxiety. Since this method for anxiety management is being implemented more and more extensively within the psychiatric care system it is important to…
- Conditions
- Anxiety State, Depression, Bipolar Depression
- Trial name
- NCT03918954
- Testing
- Virtual sensory room, Sensory room
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Vastra Gotaland Region
Depression, Primary Health Care
Effectiveness of Team Treatment of Depression in Primary Care
Most depression treatment takes place in primary care, where the condition continues to be under-detected and under-treated. A collaborative care model derived from chronic illness management theory has been successful in…
- Trial name
- NCT00012766
- Testing
- Integrated team care
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- US Department of Veterans Affairs
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Depression, Depressive Disorder
Beyond Ageing Project: A Study for the Prevention of Depression
The purpose of this study is to determine whether folate and vitamin B12, physical activity and mental health literacy can prevent depression, and folate and vitamin B12 and physical activity can prevent cognitive impairment in…
- Trial name
- NCT00214682
- Testing
- Folate (400mcg) and Vitamin B12 (100 mcg), mediated physical activity promotion, Mental health literacy
- Where
- Australia
- Volunteers
- 909 people
- Sponsor
- Australian National University
Bipolar Disorder, Bipolar Depression
Functional Assessment of Patients With Acute Bipolar Depression After 8 Months of Follow-up
This study aims to study prospectively for 8 months a sample of bipolar patients with acute depressive episode in order to identify that factors associated with functional impairment, with especial attention to the presence of…
- Trial name
- NCT01255982
- Where
- 24 sites in Spain
- Volunteers
- 249 people
- Sponsor
- AstraZeneca
Postpartum Depression, Psychoeducation
Psychoeducational Intervention to Reduce Depressive Symptoms and Strengthen Mother-Infant Bonding
The study aims to evaluate the effectiveness of a psychoeducational intervention designed within the framework of the Watson Human Caring Model in reducing postpartum depressive symptoms and creating a stronger mother-infant…
- Conditions
- Postpartum Depression, Psychoeducation, Mother-Infant Interaction
- Trial name
- NCT07062159
- Testing
- the psychoeducation intervention program, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Yasemin Ozhuner
Hydrocortisone, Depression
Exploring the Effects of Corticosteroids on the Human Hippocampus
Chronic corticosteroid (CS) exposure is associated with changes in memory and the hippocampus in both humans and in animal models.
- Conditions
- Hydrocortisone, Depression, Healthy Volunteers
- Trial name
- NCT03896659
- Testing
- Hydrocortisone Oral
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Depression
College Mental Health Project
Depression is common and debilitating disorder which, among college students, is predictive of significant problems including higher rates of dropout and suicidal behaviors.
- Trial name
- NCT03345459
- Testing
- ICare Prevent (internet-based treatment for depression in college students)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mclean Hospital
Bipolar Disorder
rTMS for Treatment of Depressed Phase of Bipolar Disorder Type II
This research study evaluates an experimental device for the treatment of the depressed phase of Bipolar Disorder Type II. Repetitive Transcranial Magnetic Stimulation (rTMS) is an experimental procedure where a device delivers…
- Trial name
- rTMS (NCT00447096)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Mental Health Issue
Effect of a Mental Wellness App on the Mental Wellness of Medical and Nurse Anesthesia Students
Mental health issues and suicide are becoming increasingly common among health care trainees and providers. Suicide is the leading cause of death among male medical residents and the second leading cause of death among female…
- Trial name
- NCT05925062
- Testing
- QActual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Anxiety, Depressive Symptoms
Brief Digital CBT for Mood and Anxiety Symptoms in Acute Psychiatric Inpatients
A randomized control trial examining the feasibility, acceptability, and preliminary efficacy of providing access to the MindShift CBT mobile app via tablet for acute psychiatric inpatients.
- Conditions
- Anxiety, Depressive Symptoms, Distress, Emotional, Anxiety and Fear
- Trial name
- NCT04841603
- Testing
- Mindshift CBT, Treatment as Usual
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre for Addiction and Mental Health