Clinical trials: Depression and Anxiety Symptom
Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms)
tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety
This study investigates if anhedonia and anxiety symptoms are associated with alterations in reinforcement learning, effort trade-offs for wins vs. punishments, and foraging behavior under threat.
- Conditions
- Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms), Depressive Disorders (With High Anhedonia Symptoms), Comorbid Depression and Anxiety Disorder (With High Anhedonia and High Anxiety Symptoms)
- Trial name
- NCT07476469
- Testing
- tVNS
- Where
- Germany
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dr. Nils B. Kroemer
Child Anxiety, Depression
Kind Minds Program for Youth With Anxiety and Depression
Rates of anxiety and depression in youth are substantial, causing a major unmet need for effective interventions. Participation in mindfulness interventions has been demonstrated to reduce anxiety and depressive symptoms among…
- Trial name
- KMP (NCT05353751)
- Testing
- Kind Minds Program
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Los Angeles
Anxiety, Panic Disorder
Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders
This study aims to investigate the etiology of anxiety, depression, and panic disorders, providing new evidence and insights into the root causes and effective treatments, potentially offering a novel approach to achieving…
- Conditions
- Anxiety, Panic Disorder, Mood Disorders, Depression
- Trial name
- NCT07268729
- Testing
- H pylori stool test, Bacterial stool analysis
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Rheumatoid Arthritis (RA), Anxiety
Mobile App-Based Yoga and Meditation in Rheumatoid Arthritis
The goal of this single-blind, randomized controlled trial is to evaluate the clinical effectiveness and short-term economic impact of a mobile application-based, personalized yoga and meditation program in adult patients with…
- Conditions
- Rheumatoid Arthritis (RA), Anxiety, Depression Anxiety Disorder, Mobile Health Technology (mHealth)
- Trial name
- NCT07666594
- Testing
- Mobile App-Based Yoga and Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Tugba Civi Karaaslan
Major Depression, Generalized Anxiety Disorder
Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months
The purpose of this study is to explore the changes in metabolic parameters in patients treated with escitalopram for six months for major depression, generalized anxiety disorder or panic disorder, with or without agoraphobia.
- Conditions
- Major Depression, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT00711737
- Where
- Singapore
- Volunteers
- 27 people
- Sponsor
- Changi General Hospital
Treatment Adherence and Compliance, Anxiety
Global Controlled Trial on Effects of an Online Self-Help Program for of Ambitious Altruists on Their Mental Health, Wellbeing, and Productivity: Comparing Versions With IFS vs. CBT, Buddy- vs. Group-, Standard- vs. Minimum-Guidance Intensity.
This study aims to compare different versions of a 16-week online self-help program in terms of their effect on self-assessed mental health, well-being, and productivity.
- Conditions
- Treatment Adherence and Compliance, Anxiety, Depression, Mental Health Issue
- Trial name
- CT_DoBetter (NCT06442072)
- Testing
- guided online self-help program
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rethink Wellbeing
Breast Cancer, Emotional Disturbances
Improving Emotion Regulation at the End of Breast Cancer Treatment
The end of treatment marks the beginning of a challenging period for breast cancer patients. While this period often provokes a sense of relief, it can also be a source of apprehension and vulnerability regarding the future.
- Conditions
- Breast Cancer, Emotional Disturbances, Emotional Dysfunction, Anxiety Depression
- Trial name
- NCT03336827
- Testing
- Cognitive-Behavioral Group Therapy and Hypnosis
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Université Libre de Bruxelles
Prostate Cancer, Creative Arts Therapy
Creative Arts Therapy on Body Image, Self-esteem, Anxiety and Depression in Post-Treatment Prostate Cancer Patients
The goal of this clinical study is to assess the feasibility of implementing a creative arts therapy intervention of drawing and painting in Hong Kong prostate cancer patients and preliminarily examine the effects of this…
- Trial name
- NCT07015866
- Testing
- Guided therapy group, Creative arts therapy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Dyspepsia
Heterogeneous Distribution of Health Literacy and Emotional State on Patients With Functional Dyspepsia.
Patients with indigestion were often found in gastroenterology clinic, those who about 20 % was caused by organic, while the rest of patients are showed abnormal inspection, and these are so called functional dyspepsia.
- Trial name
- NCT02737683
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Cyberbullying, Depression
Building Resilience in Cyberbullying Victims
This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims.
- Conditions
- Cyberbullying, Depression, Non Suicidal Self Injury, Social Anxiety
- Trial name
- Resilience (NCT04509531)
- Testing
- Wise Intervention (SA, ITP and resilience), Standard preventive intervention
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Deusto
PostPartum Depression
Curio Digital Therapy for the Treatment of Post-partum Depression
Primary Objective: Evaluate the clinical effectiveness of the MamaLift Plus app compared to control (digital sham plus treatment as usual) for the management of PPD in the observed population for a period of 9 calendar weeks.
- Trial name
- SuMMER (NCT05958095)
- Testing
- MamaLift Plus
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Healthcare Innovation Technology Lab
Anxiety and Depression
A New Intervention to Improve Function in Veterans With Anxiety and Depression
Anxiety and depression symptoms occur at high rates in Veteran populations and can significantly impact function, compromising the ability to work and to successfully form and maintain valued relationships.
- Trial name
- NCT06188923
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- VA Office of Research and Development
Crohn Disease, Pain
Pain in Patients With Crohn Disease (PAINCD)
Abdominal pain is a common symptom in patients with Crohn disease (CD). Pain is multifactorial, may result from inflammation but persists in many patients during remission.
- Conditions
- Crohn Disease, Pain, Depression, Anxiety
- Trial name
- PAINCD (NCT04488146)
- Volunteers
- 200 people
- Sponsor
- University of Liege
Depression, Anxiety
Postoperative Anxiety and Depression Among Older Chinese Patients
A multicenter, prospective observational study to describe the socioeconomic characteristics and the occurrence of postoperative anxiety and depression in the Chinese old population.
- Conditions
- Depression, Anxiety, Elderly Patients, Non-cardiac Surgery
- Trial name
- NCT06495840
- Testing
- no intervention
- Where
- China
- Sponsor
- Chinese PLA General Hospital
Anxiety, Depression
Difficulties in Emotion-regulation and Interpersonal Problems During and After the COVID-19 Pandemic
Central indicators of psychological functioning such as difficulties in emotion regulation and habitual problems in one's relating to others are likely to have been substantially impacted by the COVID-19 amelioration measures of…
- Conditions
- Anxiety, Depression, Interpersonal Problem, Emotion Regulation
- Trial name
- NCT04442282
- Volunteers
- 5,041 people
- Sponsor
- University of Oslo
Depression, Anxiety
An Online Course for Improving Knowledge and Access to Mental Health Accommodations in Canadian Enterprises
Available research on mental health accommodations within the workplace suggests that employees with mental health concerns require accommodations (e.g., flexible scheduling, quiet spaces), but only a fraction of employees will…
- Trial name
- NCT04122482
- Testing
- Psychoeducation Course
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- University of Regina
Stress Disorders, Post-Traumatic, Anxiety
Diaries for Critically Ill Patients Written by Relatives
This study will investigate the effect of diaries written by relatives for critically ill patients on the risk of posttraumatic stress symptoms.
- Conditions
- Stress Disorders, Post-Traumatic, Anxiety, Depression
- Trial name
- NCT02357680
- Testing
- Diary
- Where
- 2 sites in Denmark
- Volunteers
- 189 people
- Sponsor
- Hospitalsenheden Vest
Stress, Psychological, Anxiety
App-Based Mindfulness Meditation for People of Color Who Experience Race-Related Stress
In the United States, people of color (POC) are disproportionally affected by stressors related to race/ethnicity compared with their non-Latinx White (NLW).
- Conditions
- Stress, Psychological, Anxiety, Depression, Rumination
- Trial name
- NCT05027113
- Testing
- Mindfulness meditation
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- University of California, Los Angeles
Depression, Anxiety
RCT of the Effectiveness of Big White Wall Compared to Other Online Support
A randomised controlled trial to compare the effect on wellbeing of an online peer review website (Big White Wall) compared to freely available online information (NHS Moodzone) for people with depression and anxiety.
- Trial name
- REBOOT (NCT02902159)
- Testing
- BWW Online Peer Support, NHS Moodzone Online Information
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,200 people
- Sponsor
- University of Nottingham
Depression and Quality of Life, Treatment Resistant Depression (TRD)
Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression
This observational study investigates the use of Esketamine Intranasal Spray in patients with Treatment-Resistant Depression in Real-World Settings.
- Conditions
- Depression and Quality of Life, Treatment Resistant Depression (TRD), Anhedonia, Apathy
- Trial name
- ESKPSY (NCT07146503)
- Testing
- Esketamine (Intranasal Spray)
- Where
- 5 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Riccardo Guglielmo
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